Gene Information

Name : nrdF (KP1_4270)
Accession : YP_002920867.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 4101432 - 4102433 bp
Length : 1002 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
TTGAAGGCTGCGTGTCCTGCGCGCTGTAAGGAGAACAGGATGACCCATTTAACGCGCGTCAGCGCAATCAACTGGAACCG
CATTGATGACGATAAAGATCTTGAGGTCTGGAACCGTCTCACCAGCAACTTCTGGCTGCCGGAGAAAGTGCCGCTGTCGA
ACGACATTCCCGCCTGGCAAACCCTCAGCGCGGCGGAGCAGCAGTTGACCATTCGCGTCTTTACCGGATTGACCCTGCTT
GACACCATTCAGAACACCGTCGGCGCCCCGGCGCTAATGGCGGACGCCTTAACCCCGCATGAGGAGGCGGTGCTGTCGAA
CATCAGCTTTATGGAGGCGGTTCATGCCCGCTCTTACAGCTCCATCTTTTCCACGCTGTGCCACAGCAAGGAAGTGGATG
CCGCCTTCGCCTGGAGCGAAAGCTGCGATCCTCTGCAGCGCAAGGCGCAGCTGATGCTGGGTTACTATCAGGCCGACGAG
CCGCTGAAGAAAAAAATCGCCAGCGTGTTCCTCGAATCCTTTCTCTTCTACTCCGGCTTCTGGCTGCCGATGTACTTCTC
CAGCCGGGGAAAGCTGACCAACACTGCGGATCTGATCCGCCTGATCATTCGCGATGAAGCGGTGCATGGCTATTACATCG
GCTACAAGTACCAGAAAGGACTGGAGATCGTCAGCCCCGGCAAGCGCGAAGAATTGAAAAATTTCGCCCTCGATCTGCTG
ATGGATCTTTACGACAACGAACTGGCCTACAGCCGGGAGCTGTACGGCGAGAGCGGCTGGTTCGACGACGTCAGCGCTTT
CCTGTGCTACAACGCCAACAAAGCGCTGATGAACCTCGGCTACGAGGCGCTGTTCCCGGCGGAGATGGCGGCGGTCAATC
CGGCAATCCTCGCAGCGCTGTCGCCCAACGCCGACGAAAACCATGACTTTTTCTCCGGTTCCGGCTCCTCCTACGTGATA
GGAAAAATGGAAGAGACCGCCGACGACGATTGGGACTTTTAA

Protein sequence :
MKAACPARCKENRMTHLTRVSAINWNRIDDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQQLTIRVFTGLTLL
DTIQNTVGAPALMADALTPHEEAVLSNISFMEAVHARSYSSIFSTLCHSKEVDAAFAWSESCDPLQRKAQLMLGYYQADE
PLKKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKGLEIVSPGKREELKNFALDLL
MDLYDNELAYSRELYGESGWFDDVSAFLCYNANKALMNLGYEALFPAEMAAVNPAILAALSPNADENHDFFSGSGSSYVI
GKMEETADDDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 1e-105 65