Gene Information

Name : nrdE (KP1_4269)
Accession : YP_002920866.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : -
Position : 4099319 - 4101460 bp
Length : 2142 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGGCAACGACAACCGCAGAACGTATAACCGCCGCCGTGGATTTTCACGCCCTCAACGCGATGCTGAATTTGTACGACAG
CGAGGGCCGCATCCCGTTTGAGAAAGATCGCCAGGCGGTTGAGGCCTTTATGGCGACCCAGGTTCAGCCCAACACCCTCA
CCTTCCCCAGCCAGGAGGATAAGCTCAGCTGGCTCGTCAGCGAGGGCTATTACGATCCGCAGGTGCTGGCCGGCTATGAC
CGCGGGTTTGTGCTGGCGTTGTTCGCCCATGCCCGGCGCGCTCCGTTTCGCTTTCAGACCTTCCTCGGCGCCTGGAAGTT
CTATACCAGCTATGCGCTGAAGACCTTTGACGGCAAGCACTACCTCGAGGATTTCGCCGAACGCAGCGTGATGGTGGCCC
TGACGCTGGCCCGGGGCGATGAACAGCAGGCGCGGCAGCTGACGGAGGAGATACTCAGCGGCCGCTTTCAGCCCGCCACA
CCGACCTTCCTTAACGCTGGCAAACAGCAGCGCGGGGAGCTGATCTCCTGCTTCCTGCTGCGTATTGAGGATAATATGGA
GTCCATCGGCCGGGCGGTGAACTCGGCGCTACAGCTGTCGAAGCGCGGCGGCGGGGTGGCCTTTTTACTCTCCAACCTGC
GCGAGGCCGGGGCGCCGATCAAGCGCATCGAAAACCAGTCTTCTGGGGTGGTGCCGGTGATGAAGATGCTGGAGGACGCC
TTCTCCTATGCCAATCAGCTCGGCGCCCGCCAGGGGGCGGGTGCGGTCTGGCTGCATGTTCACCATCCCGATATTTTACG
CTTTCTTGATACCCGGCGTGAAAATGCCGATGAGAAAATCCGCATCAAAACCTTGTCGCTGGGGGTGGTGATCCCTGATA
TCACCTTCCAGCTGGCGAAAGAAGATGCGCAGATGGCCCTGTTCTCGCCTTATGACGTCGAACGGCTGTACGGCAAACCT
TTCGCCGATTGCGCCATCGGCGACCTCTATCCGCAGCTGGTGGCCGACGAGCGGGTCCGCAAACGCTGGATCCGCGCCCG
CGACCTGTTCCAGCGCCTGGCGGAGATCCAGTTTGAATCCGGCTACCCGTACATCATGTTTGAAGACACCGTGAACCGCG
CCAGTCCGGTGGCCGGGCGGGTCACCATGAGCAATCTGTGTTCGGAGATCCTGCAGGTCAGTACGCCGTCCGCCTATAAT
GAAGACCTCAGCTATGCCCATATCGGGGAAGATATCTCCTGCAACCTCGGCTCGCTGAACATCGCCCATACCATGGACTC
GCCGGATTTCGGCCGCACAATCGCCACCGCGGTGCGCGCCCTGACCGCCGTGTCCGACATGAGCCACATTCAGTCGGTTC
CCTCGGTGGCGGCCGGCAACGCGGCCTCCCACGCCATCGGCCTGGGGCAGATGAATCTGCACGGTTACCTGGCGCGGGAG
GGCATTGCCTACGGCAGCCCGGAGGGGCTGGACTTCACCAATATCTACTTCTACACCGTGACCTGGCACGCGCTGCACAC
CTCGATGCAGCTGGCCCGCGAGCGCGGCCAGCGCTTCGCCGGCTTCGAGCAGTCGCGCTACGCCAGCGGGGCGTACTTCG
ACAAATATCTGCAGGAGGAGTGGCAGCCGAAAACCGAACGGGTGCGCACGCTGTTCGCCCGCGCCGGCATCTCTCTGCCC
GACCGGGAAAGCTGGCGCCAGCTGCGCGACGATGTCATGCGCTATGGCATCTACAATCGCTATCTGCAGGCGGTGCCGCC
CACCGGCTCGATCTCGTACATCAACCATGCCACCTCCAGCATTCACCCGATCGTCTCGAAGATTGAGATCCGCAAAGAGG
GGAAAACCGGGCGAGTGTACTACCCCGCGCCATTTATGAATAACGACAATCTGGCCCTCTACCAGGATGCGTATGAGATA
GGGCCGGAGAAGATCATTGACACTTACGCCGAGGCGACGCGCCACGTCGACCAGGGGCTGTCGCTGACCCTGTTCTTCCC
CGATACCGCCACCACCCGCGATATCAACAAGGCGCAAATTTACGCCTGGAAGAAAGGCATCAAGACGCTCTACTACATCC
GTCTGCGCCAGCTGGCGCTGGAAGGCACTGAAATTGAAGGCTGCGTGTCCTGCGCGCTGTAA

Protein sequence :
MATTTAERITAAVDFHALNAMLNLYDSEGRIPFEKDRQAVEAFMATQVQPNTLTFPSQEDKLSWLVSEGYYDPQVLAGYD
RGFVLALFAHARRAPFRFQTFLGAWKFYTSYALKTFDGKHYLEDFAERSVMVALTLARGDEQQARQLTEEILSGRFQPAT
PTFLNAGKQQRGELISCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVVPVMKMLEDA
FSYANQLGARQGAGAVWLHVHHPDILRFLDTRRENADEKIRIKTLSLGVVIPDITFQLAKEDAQMALFSPYDVERLYGKP
FADCAIGDLYPQLVADERVRKRWIRARDLFQRLAEIQFESGYPYIMFEDTVNRASPVAGRVTMSNLCSEILQVSTPSAYN
EDLSYAHIGEDISCNLGSLNIAHTMDSPDFGRTIATAVRALTAVSDMSHIQSVPSVAAGNAASHAIGLGQMNLHGYLARE
GIAYGSPEGLDFTNIYFYTVTWHALHTSMQLARERGQRFAGFEQSRYASGAYFDKYLQEEWQPKTERVRTLFARAGISLP
DRESWRQLRDDVMRYGIYNRYLQAVPPTGSISYINHATSSIHPIVSKIEIRKEGKTGRVYYPAPFMNNDNLALYQDAYEI
GPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWKKGIKTLYYIRLRQLALEGTEIEGCVSCAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 69