Gene Information

Name : aldB (KP1_4252)
Accession : YP_002920849.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4086429 - 4087949 bp
Length : 1521 bp
Strand : -
Note : internal ID: KP4252

DNA sequence : 
ATGCGTTATGCACATCCTGGCCAGCCCGGCGCCGTGGTTTCATTTAAATCGGCTTACGGCAACTTTATTGACGGTAGATT
TGTCGAGCCGCTGAGCGGCGAATTCTTTATGAATACTTCGCCGGTCGACGGCAGCAACATTGCGCAGTTTCCCCGCTCGG
ATGCCAGAGACATTGACTTCGCCCTCGACGCCGCCCATCGCGCGGCGCCGGCGTGGGGTAAAACCTCAGTGCAACAGCGC
TCCAGGCTGCTGCTACAGGTCGCCGATCGTATTGAACAGCATCTGGAATATCTGGCGGTGGCGGAGAGCTGGGACAATGG
GAAACCGATCCGCGAAACCCTGAATGCCGACCTGCCGCTGGCGGTGGACCATTTTCGCTACTTCGCCGGCTGCCTGCGCG
CTCAGGAGGGAAGCACCGCCGAGATTGACGAAACCACGGTGGCCTATCATTTCCATGAACCGCTGGGGGTGGTCGGGCAG
ATTATCCCGTGGAACTTCCCGCTGCTGATGGCCGCGTGGAAGCTGGCCCCGGCCCTGGCGGCGGGGAACTGCGTGGTGCT
CAAACCGGCGGAACAGACGCCGCTAAGCATTACCCTGCTGCTGGAGCTGATAGGCGATCTGTTCCCGGCCGGGGTGCTTA
ACGTGGTGCAGGGTTTCGGCAAAGAGGCGGGCGAGGCGCTGGCCACCAGCAAGCGTATCGCCAAGCTGGCGTTTACCGGC
TCCACGCCGGTCGGGCGGCATATTCTCGCCTGCGCGGCGGAAAATATTATCCCCTGCACCGTCGAGCTGGGGGGGAAATC
GCCCAACATCTACTTCGCCGACGTGATGGACGGAGAAGAGGAATTTATTGAGAAGGCGGTGGAGGGGCTGGTGCTCGGCT
TCTTCAACCAGGGTGAGGTCTGTACCTGCCCGTCGCGGGCGCTGATCCATGAATCCATCTATGAGCCCTTTATGGCACGG
GTCATGGAGAAGGTGGCGCAGATCCGCCGCGGCGATCCGTTAGATACCGACACCATGATCGGCGCTCAGGCTTCCCGCCA
GCAGTTCGACAAGATCCTCTCCTATATTCAGATTGCCCGGGAAGAGGGTGGGCAAATTCTGACCGGAGGCGAGCGGGCGG
CTATCGCGCCGGCGCTGGATAATGGCTTTTATATTCAGCCCACGCTGATTAAAGGTCGCAACGATATGCGCTCCTTCCAG
GAGGAGATCTTTGGGCCGGTGATCGGGGTGACCACCTTTAAGGACGAAGCGGAAGCGCTGACCATCGCCAATGAGACCCA
GTTTGGTCTCGGCGCCGGGGTGTGGACGCGGGATACCAACCTCGCCTATCGCATGGGTCGCGGCATTAAAGCCGGTCGCG
TGTGGACCAACTGCTATCATGTCTACCCGGCGCATGCGGCGTTCGGCGGCTATAAACAGTCCGGCGTCGGGCGGGAAACG
CACAAGATGGCGCTGGATGCCTATCAGCAAACCAAAAACCTGCTGGTGAGCTACGGCACCGCGCCGCTGGGCCTGTTCTG
A

Protein sequence : 
MRYAHPGQPGAVVSFKSAYGNFIDGRFVEPLSGEFFMNTSPVDGSNIAQFPRSDARDIDFALDAAHRAAPAWGKTSVQQR
SRLLLQVADRIEQHLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGSTAEIDETTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLSITLLLELIGDLFPAGVLNVVQGFGKEAGEALATSKRIAKLAFTG
STPVGRHILACAAENIIPCTVELGGKSPNIYFADVMDGEEEFIEKAVEGLVLGFFNQGEVCTCPSRALIHESIYEPFMAR
VMEKVAQIRRGDPLDTDTMIGAQASRQQFDKILSYIQIAREEGGQILTGGERAAIAPALDNGFYIQPTLIKGRNDMRSFQ
EEIFGPVIGVTTFKDEAEALTIANETQFGLGAGVWTRDTNLAYRMGRGIKAGRVWTNCYHVYPAHAAFGGYKQSGVGRET
HKMALDAYQQTKNLLVSYGTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-154 66
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-161 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-161 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-161 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-160 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-57 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_002920849.1 aldehyde dehydrogenase B VFG0082 Protein 4e-155 66