Gene Information

Name : tktB (KP1_4050)
Accession : YP_002920661.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 3870235 - 3872268 bp
Length : 2034 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGCCGCCAAACTGTCACTTTAGTCTCACGGAGAAAAATATGTCCCGAAGAGAGCTTGCCAACGCCATCCGCGCCCTGAG
TATGGACGCCGTGCAGAAAGCCAACTCCGGCCATCCCGGTGCGCCGATGGGGATGGCTGATATTGCCGAAGTGCTGTGGA
ACGATTTTCTCAAGCACAATCCGCAGAACCCTGACTGGGTGGACCGCGACCGCTTTATCTTGTCCAACGGCCACGCGTCG
ATGCTGCTCTACAGTCTGCTGCACCTGACCGGCTACGATCTGCCGCTGTCTGAACTGAAGCAGTTCCGTCAGCTGCACTC
TAAAACGCCCGGCCACCCGGAGCATGGCTATCCCCCTGGGGTGGAAACCACCACCGGCCCGCTGGGCCAGGGGCTGGCGA
ACGCCGTTGGGATGGCCATCGCCGAACGGACGCTGGCGGCGCAGTTTAATCGCCCCGGCCATGAGATCATTGACCATCAC
ACCTGGGTGTTCATGGGCGATGGCTGTTTGATGGAGGGGATCTCCCATGAGGCCTGTTCGCTGGCCGGCACGCTCGGACT
GGGCAAGCTGATCGGTTTTTACGATCACAACGGCATCTCCATCGACGGCAAAACCGAAGGCTGGTTTTCCGATGATACGG
CGGAACGCTTCCGCGCCTATCACTGGCACGTCATAGGCGATATCGACGGCCACGATCCGCAGGCTATCAAACAGGCGATA
ACGGAAGCGCAGGCGGTGAAAGATAAACCGTCACTGATTATCTGCCGGACCATCATCGGCTTCGGTTCGCCCAACAAAGC
CGGCTCAGAGGAGTCTCACGGGGCGGCGCTGGGCGAAAAAGAGGTAGCGCTGGCCCGCCAGCAGCTTGGCTGGAAATATC
CTCCGTTCGAGATCCCGAAAGAGATCTACGCGGGCTGGGATGCGCGTCCGCGCGGGGAAAAAGCGGAGCACGCCTGGAAC
GAGAAATTCGCCGCCTACCAGCAGCAGTTCCCGGAGCTGGCCGCTGAGCTGACCCGACGTATGAATGGCGCCCTGCCGGA
AGACTTTGCCGCGATCGCCCGCGACTACGTGGCGAAACTGCAGGCCGAGCCGGCGAAAATCGCCAGCCGCAAGGCTTCGC
AAAACGCGCTGAACGCCTACGGCCCGCACCTCCCGGAACTGCTGGGCGGTTCTGCGGATCTTGCGCCGAGTAACCTGACC
ATCTGGTCTGGATCGACATCGATTAAAGAAGATCCTGCGGGCAATTATATCCACTACGGGGTGCGCGAGTTTGGCATGAC
CGCGGTGGCCAACGGCATTGCCCTGCACGGGGGCTTTATTCCTTATACCTCGACCTTCCTGATGTTTGTGGAGTACGCCC
GCAACGCCGCGCGCATGGCAGCCCTGATGAAGGCCCGGCAGATCATGGTCTATACCCATGACTCGATCGGTCTTGGGGAA
GACGGGCCGACGCACCAGGCGGTGGAACAGCTGGCCAGTCTGCGGCTGACGCCCAACTTCAGCACCTGGCGCCCCTGCGA
CCAGGTGGAGACCGCCGTCGCCTGGCAGGCGGCTATCGCGCGACAGGGCGGGCCGACGGCGCTGATCCTGTCGCGACAAA
ACCTGGCGCAGATGCCGCGTACCCCGGAACAGGTGCAGGATATCGCCCGGGGTGGCTACGTGCTTAAGGATGCCGGCGGC
AAGCCCGACCTGATCCTCATCGCCACCGGCTCGGAAGTGGAGATCACCGTCCTGGCCGCGGAAAAACTGTTGGCCAAAGG
GGTAAATGTGCGGGTCGTCTCGCTCCCTTCCACTGATGTGTTTGACGCCCAGGATGAGGCCTGGCGCGAATCCGTGCTGC
CATCGGACGTCAGCGCCCGGGTGGCGGTCGAAGCCGGGATAGCGGACTACTGGTATAAATATGTCGGCTTAAAAGGCAAG
ATCGTCGGCATGACCGGCTATGGCGAATCCGCCCCGGCAGAGCAGTTGTTCCCGTTCTTTGGCTTTACGGTCGACCATAT
CGTCGCCACCGCCGAACAGGTGCTTAACGGGTGA

Protein sequence :
MPPNCHFSLTEKNMSRRELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPQNPDWVDRDRFILSNGHAS
MLLYSLLHLTGYDLPLSELKQFRQLHSKTPGHPEHGYPPGVETTTGPLGQGLANAVGMAIAERTLAAQFNRPGHEIIDHH
TWVFMGDGCLMEGISHEACSLAGTLGLGKLIGFYDHNGISIDGKTEGWFSDDTAERFRAYHWHVIGDIDGHDPQAIKQAI
TEAQAVKDKPSLIICRTIIGFGSPNKAGSEESHGAALGEKEVALARQQLGWKYPPFEIPKEIYAGWDARPRGEKAEHAWN
EKFAAYQQQFPELAAELTRRMNGALPEDFAAIARDYVAKLQAEPAKIASRKASQNALNAYGPHLPELLGGSADLAPSNLT
IWSGSTSIKEDPAGNYIHYGVREFGMTAVANGIALHGGFIPYTSTFLMFVEYARNAARMAALMKARQIMVYTHDSIGLGE
DGPTHQAVEQLASLRLTPNFSTWRPCDQVETAVAWQAAIARQGGPTALILSRQNLAQMPRTPEQVQDIARGGYVLKDAGG
KPDLILIATGSEVEITVLAAEKLLAKGVNVRVVSLPSTDVFDAQDEAWRESVLPSDVSARVAVEAGIADYWYKYVGLKGK
IVGMTGYGESAPAEQLFPFFGFTVDHIVATAEQVLNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 71
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 66