Gene Information

Name : ybtS (KP1_3583)
Accession : YP_002920243.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Virulence
Product : salicylate synthase Irp9
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 3397453 - 3398757 bp
Length : 1305 bp
Strand : -
Note : catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin

DNA sequence :
ATGAAAATCAGTGAATTTCTACATCTGGCGTTACCAGAGGAACAATGGCTACCGACGATTTCTGGCGTTTTACGCCAGTT
CGCAGAAGAAGAGTGTTATGTCTATGAGCGTCAACCCTGTTGGTATTTAGGCAAAGGGTGCCAGGCACGGCTGCACATTA
ATGCCGACGGAACGCAGGCGACATTTATTGATGATGCCGGGGAGCAAAAATGGGCGGTGGATTCCATTGCCGACTGCGCG
CGTCGTTTTATGGCGCATCCTCAGGTGAAAGGACGTCGGGTATATGGACAGGTTGGGTTCAACTTTGCGGCGCATGCGCG
GGGGATTGCCTTTAACGCCGGGGAGTGGCCGCTGCTGACGTTAACCGTTCCCCGTGAAGAACTTATTTTTGAAAAGGGAA
ATGTCACCGTTTATGCGGACTCCGCCGACGGGTGCCGACGTTTGTGCGAGTGGGTAAAAGAGGCCGGTACAACGACGCAG
AACGCACCACTGGCGGTGGATACCGCCCTCAATGGTGAGGCATATAAACAACAGGTTGCGCGCGCCGTTGCGGAGATCCG
CCGTGGCGAGTATGTCAAAGTGATTGTCTCGCGCGCCATTCCCCTGCCATCGCAGATTGATATGCCCGCCACGCTGTTAT
ACGGGCGGCAGGCGAACACACCTGTGCGCTCGTTTATGTTCCGTCAGGAAGGACGCGAAGCGCTGGGCTTTAGCCCGGAA
CTGGTGATGTCAGTGACGGGCAATAAAGTGGTCACTGAACCGCTTGCGGGCACCCGCGATCGCATGGGAAACCCGGAGCA
TAATAAGGCGAAAGAGGCAGAACTGTTGCACGACAGTAAAGAGGTGCTTGAGCATATCCTTTCTGTCAAAGAAGCTATTG
CTGAACTGGAGGCCGTTTGCCAGCCGGGCAGCGTGGTGGTTGAAGATTTAATGTCGGTTCGCCAGCGCGGCAGCGTTCAG
CATCTGGGGTCTGGCGTGAGCGGTCAGCTTGCGGAAAACAAGGATGCCTGGGATGCGTTTACCGTGCTGTTTCCGTCGAT
TACCGCCTCAGGTATCCCTAAAAATGCTGCTCTGAACGCGATTATGCAAATTGAGAAGACGCCGCGAGAGCTTTATTCCG
GCGCAATCCTGCTGCTGGACGATACGCGCTTTGATGCGGCGCTAGTTCTGCGTTCCGTATTTCAGGATAGCCAGCGCTGC
TGGATACAGGCGGGGGCGGGAATCATCGCGCAATCTACGCCGGAACGCGAACTGACAGAAACCCGGGAGAAATTAGCGAG
CATTGCGCCCTATTTAATGGTGTAG

Protein sequence :
MKISEFLHLALPEEQWLPTISGVLRQFAEEECYVYERQPCWYLGKGCQARLHINADGTQATFIDDAGEQKWAVDSIADCA
RRFMAHPQVKGRRVYGQVGFNFAAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGCRRLCEWVKEAGTTTQ
NAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSQIDMPATLLYGRQANTPVRSFMFRQEGREALGFSPE
LVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQ
HLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRSVFQDSQRC
WIQAGAGIIAQSTPERELTETREKLASIAPYLMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtS NP_993012.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
APECO1_1052 YP_853070.1 salicylate synthase Irp9 Not tested PAI IV APEC-O1 Protein 0.0 99
ybtS YP_002346907.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS NP_669701.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS YP_070129.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS CAA21385.1 - Virulence HPI Protein 0.0 99
irp9 CAB46570.1 salicylate synthetase, Irp9 Virulence HPI Protein 0.0 99
irp9 YP_001006810.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
unnamed AAD17661.1 unknown Not tested HPI Protein 0.0 93