Gene Information

Name : glnA (KP1_0030)
Accession : YP_002917017.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : -
Position : 34991 - 36400 bp
Length : 1410 bp
Strand : -
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGTCCGCTGAACACGTTTTGACGATGCTGAACGAGCACGAAGTGAAGTTTGTCGATCTGCGCTTCACCGATACCAAAGG
TAAAGAACAGCACGTCACGATTCCGTCTCATCAGGTAAATGCCGAATTCTTCGAAGAAGGCAAAATGTTTGATGGCTCCT
CGATTGGTGGCTGGAAAGGTATCAACGAATCTGACATGGTCCTGATGCCGGACGCGTCCACCGCGGTCATTGACCCGTTC
TACGAAGAACCGACCCTGATCATCCGCTGCGATATCCTCGAGCCAGGCACCCTGCAGGGCTATGACCGTGACCCGCGCTC
CATCGCGAAACGCGCTGAAGAGTACCTGCGCGCCACCGGCATCGCTGATACCGTCCTGTTCGGGCCAGAACCAGAATTCT
TCCTGTTCGACGACATCCGTTTTGGCGCCTCTATCTCCGGCTCCCATGTCGCGATCGATGACATTGAAGGTGCGTGGAAC
TCCTCCACCAAATACGAAGGCGGTAACAAAGGTCACCGTCCGGGCGTGAAAGGGGGTTACTTCCCGGTTCCGCCAGTAGA
CTCTTCTCAGGACATCCGTTCCACCATGTGTATGATCATGGAAGAGATGGGTCTGGTTGTTGAAGCCCATCACCATGAAG
TAGCAACCGCAGGTCAGAACGAAGTGGCAACCCGCTTCAATACCATGACCAAAAAAGCGGATGAAATTCAGATTTACAAA
TACGTTGTTCACAACGTCGCTCACCGCTTTGGTAAAACCGCGACCTTTATGCCGAAACCGATGTTCGGCGACAACGGCTC
CGGCATGCACTGCCATATGTCTCTGGCGAAAAACGGTACCAACCTGTTCTCCGGCGACAAATACGCCGGTCTGTCTGAGC
AGGCGCTGTTCTACATCGGCGGCGTAATCAAACACGCTAAAGCCATCAACGCCCTGGCGAACCCGACCACCAACTCCTAC
AAGCGTCTGGTCCCGGGTTACGAAGCGCCGGTTATGCTGGCTTACTCTGCCCGTAACCGCTCTGCCTCTATCCGTATTCC
GGTGGTGACCTCTCCGAAAGCGCGTCGTATCGAAGTGCGCTTCCCGGACCCGGCTGCCAACCCGTACCTGTGCTTTGCGG
CGCTGCTGATGGCTGGCCTTGATGGTATCAAGAACAAAATCCATCCGGGCGAAGCAATGGATAAAAACCTGTATGACCTG
CCGCCGGAAGAAGCGAAAGAGATCCCGCAGGTTGCCGGTTCTCTGGAAGAAGCCCTGCAGGCCCTGGATGCTGACCGCGA
GTTCCTGACCGCTGGCGGCGTGTTCACCAATGACGCTATCGATGCCTACATCGCCCTGCGTATGGAAGAGAACGACCGCG
TACGCATGACTCCGCATCCGGTTGAGTTCGAACTGTACTACAGCGTCTAA

Protein sequence :
MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPSHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPF
YEEPTLIIRCDILEPGTLQGYDRDPRSIAKRAEEYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWN
SSTKYEGGNKGHRPGVKGGYFPVPPVDSSQDIRSTMCMIMEEMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALFYIGGVIKHAKAINALANPTTNSY
KRLVPGYEAPVMLAYSARNRSASIRIPVVTSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDL
PPEEAKEIPQVAGSLEEALQALDADREFLTAGGVFTNDAIDAYIALRMEENDRVRMTPHPVEFELYYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 1e-102 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_002917017.1 glutamine synthetase VFG1399 Protein 1e-115 51