Gene Information

Name : umuC (KP1_2206)
Accession : YP_002918971.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : -
Position : 2126902 - 2128167 bp
Length : 1266 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTCGCGCATTGTGATGTGAACGCCTTCTATGCCAGCTGTCAGACCGCCTTCCGGCCAGACCTGAAGGGGCGGCCGGT
GGTGGTGCTGTCGAACAACGACGGCTGCGTGATCGCCCGCTCGGCGGAGGCGAAGCCGTTTGTGAAAATGGGCGAACCCT
ACTTTAAGCAGAAGGCTGCGTTTCTTCGCCACGGCGTCGTGGCGTTTAGCAGTAATTATGAGCTGTATGCCGACATGTCC
AGCCGGGTGATGGCCACCCTGGAAGAGCTCACCCCGCGCTGCGAAATTTACAGTATCGATGAGGCCTTTTGCGATGTCAG
CGGTGTGCGTCATTGCAGAGATCTGACCGATTTTGGCCGCGAAATCCGCGCCACGGTGCTGCAGCGTACCCATCTGACGC
TGGGCGTTGGCATCGCCCCGACCAAAACCCTGGCGAAGCTGGCCAACCACGCGGCGAAGCAGTGGCCGCGGCAGACGGGC
GGGGTAGTGGACTTGTCCTGCCCGCAGCGGCAGCGAAAGCTGATGGCGCTGCTGCCGGTGAGCGAGGTCTGGGGCATCGG
GCGGCGGATCGGCAAAAAGCTTGAAGCGATGGGGATCGGCACGGTACTCCAGCTGGCGGAGAGCGATATCCGCTTTATCC
GCAAGCACTTCACGGTGGTGCTCGAACGAACGGTACGGGAGCTGCGCGGCGAGCCTTGCCTGGCGCTGGAGGAGTTTGCC
CCCGCTAAGCAGGAAATTATCTGCAGCCGCTCGTTCGGGGATCGGATTACGGCCTATGAGGATATGCGCCAGGCGATCTG
CAGCTATGCCGCGCGGGCAGCAGAAAAGCTGCGCGGTGAGCATCAGTACTGCCGGTTCGTCTCCGCCTTTGTCAAAACCA
GCCCCTTCGCGCTGAATGAACCCTATTACGGCAACAGCGCCTCGCTAAAGCTGCTGACGCCGACCCAGGACTCCCGAGAT
ATTATCGCCGCGGCGACGAGCTGTCTGGATGCCATCTGGAAAGCGGGGCATCGCTATCAGAAGGCCGGCGTGATGCTCGG
CGATTTCTACAGCCAGGGCGTCGCCCAGCTGAATCTGTTCGACGAGCTTGCTCCGCGGCACAACAGCGCCAGACTGATGC
AGGTTCTCGATCAGCTGAATGCGAAAAACGGCAGGGGGGCGCTCTATTTTGCCGGCCAGGGGATCCAGCAGCAGTGGCAG
ATGAAGCGAGAGATGCTCTCGCCGCGCTACACCACGCGATACGGCGACCTGCTCCGCGTCAGATAA

Protein sequence :
MFAHCDVNAFYASCQTAFRPDLKGRPVVVLSNNDGCVIARSAEAKPFVKMGEPYFKQKAAFLRHGVVAFSSNYELYADMS
SRVMATLEELTPRCEIYSIDEAFCDVSGVRHCRDLTDFGREIRATVLQRTHLTLGVGIAPTKTLAKLANHAAKQWPRQTG
GVVDLSCPQRQRKLMALLPVSEVWGIGRRIGKKLEAMGIGTVLQLAESDIRFIRKHFTVVLERTVRELRGEPCLALEEFA
PAKQEIICSRSFGDRITAYEDMRQAICSYAARAAEKLRGEHQYCRFVSAFVKTSPFALNEPYYGNSASLKLLTPTQDSRD
IIAAATSCLDAIWKAGHRYQKAGVMLGDFYSQGVAQLNLFDELAPRHNSARLMQVLDQLNAKNGRGALYFAGQGIQQQWQ
MKREMLSPRYTTRYGDLLRVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 6e-128 64
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 6e-128 64
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 9e-91 49
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-73 47