Gene Information

Name : tktA (KP1_2123)
Accession : YP_002918898.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 2065422 - 2067428 bp
Length : 2007 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAAAACGACAAATACCACTCGCCGCCAATGCGCCAACGCGCTGCGCGCCCTGAGCATGGACGCTGTACAGAAAGCCAA
ATCCGGCCACCCGGGGGCCCCGATGGGTATGGCTGACATTGCCGAAGTGCTGTGGCGTGATTTCCTGAACCATAACCCGA
ACAATCCGGCCTGGGCTGACCGTGACCGTTTTGTGTTGTCAAATGGCCATGGTTCGATGCTGATTTACAGCCTGCTGCAC
CTCACTGGCTACGATCTGCCGATATCCGAGCTGAAAAACTTCCGCCAGCTGCACTCCAAAACCCCGGGTCACCCGGAAGT
CGGCTACACCGCAGGCGTGGAAACCACCACCGGTCCGCTGGGCCAGGGTATCGCTAACGCGGTCGGGATGGCTATCGCCG
AGAAAACCCTGGCGGCGCAGTTCAACCGTCCGGGACACGATATCGTCGACCACTACACCTACGCCTTCATGGGCGACGGC
TGCATGATGGAAGGCATTTCTCACGAAGTGTGCTCCCTGGCCGGTACCCTGAAACTGGGTAAACTGGTGGCGTTCTATGA
TGACAACGGCATCTCCATCGACGGCCACGTTGAAGGCTGGTTCACCGACGACACCGCCAAACGCTTTGAAGCCTACGGCT
GGCACGTGGTGCGCGGCGTGGACGGTCACGACGCTGACGCCATCAAACGCGCGGTAGAAGAAGCGCGGGCGGTCACCGAC
AAACCGTCCCTGCTGATGTGCAAAACCATCATCGGTTTCGGTTCGCCGAACAAAGCCGGCACCCACGACTCCCACGGCGC
GCCGCTCGGCGACGCCGAAATCGCCCTGACCCGCGAAGCGCTGGGCTGGAAACACGCGCCGTTTGACATCCCGTCTGACA
TCTATGCCCAGTGGGATGCCAAAGAAGCCGGCCAGGCGAAAGAAGCGGCGTGGAATGAGAAGTTCGCTGCCTACGCCAAA
GCCTTCCCGCAGGAAGCAGCCGAATTCACCCGCCGTATGAAAGGCGAGATGCCGTCTGACTTCGATGCGAAAGCTAACGA
GTTCATCGCGAAGCTGCAGGCCAACCCGGCGAAAATCGCCAGCCGTAAAGCCTCGCAGAACGCCATCGAAGCCTTCGGCC
CGCTGCTGCCGGAATTCCTCGGCGGCTCCGCAGATCTCGCGCCGTCCAACCTGACCCTGTGGTCCGGTTCTAAGCCGATC
AACGAAGACGCTGCCGGGAACTACATCCACTACGGCGTGCGCGAGTTCGGTATGACCGCTATCGCCAACGGTATCGCGCT
GCACGGCGGCTTCCTGCCGTACACCTCCACCTTCCTGATGTTCGTGGAATACGCGCGTAACGCGGTACGTATGGCCGCGC
TGATGAAACAGCGTCAGGTGATGGTCTACACCCACGACTCGATCGGTCTGGGCGAAGACGGCCCGACTCACCAGCCGGTA
GAGCAGGTGGCTTCCCTGCGCGTGACCCCGAACATGTCCACCTGGCGTCCGTGTGACCAGGTGGAATCCGCGATTGCGTG
GAAATATGGCGTGGAGCGTCAGGACGGCCCGACCGCGCTGATCCTCTCCCGTCAGAACCTGGCGCAGCAGGAGCGTACCG
CAGAGCAGCTGGCGAACGTGGCCCGCGGCGGTTATGTGCTGAAAGAGTGCACCGGCTCGCAGCCGGAGCTGATCTTCATC
GCCACCGGTTCAGAAGTGGAGCTGGCGGTTGCCGCGTGGGACAAACTGACTGCCGAAGGCGTGAAGGCGCGCGTGGTTTC
CATGCCGTCCACCGACGCGTTCGACAAGCAGGATGCGGCTTATCGCGAATCCGTACTGCCGAAAGCCGTGACCGCGCGCG
TTGCCGTGGAAGCGGGTATCGCTGACTACTGGTTCAAATACGTTGGCCTGAACGGCGCTATCGTTGGCATGACCACCTTC
GGTGAGTCTGCGCCGGCTGAGCAGCTGTTCGAGGAGTACGGCTTCACCGTCGATAACGTGGTTGCTAAAGCGAAAGCACT
GCTGTAA

Protein sequence :
MKTTNTTRRQCANALRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLNHNPNNPAWADRDRFVLSNGHGSMLIYSLLH
LTGYDLPISELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDG
CMMEGISHEVCSLAGTLKLGKLVAFYDDNGISIDGHVEGWFTDDTAKRFEAYGWHVVRGVDGHDADAIKRAVEEARAVTD
KPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREALGWKHAPFDIPSDIYAQWDAKEAGQAKEAAWNEKFAAYAK
AFPQEAAEFTRRMKGEMPSDFDAKANEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKPI
NEDAAGNYIHYGVREFGMTAIANGIALHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPV
EQVASLRVTPNMSTWRPCDQVESAIAWKYGVERQDGPTALILSRQNLAQQERTAEQLANVARGGYVLKECTGSQPELIFI
ATGSEVELAVAAWDKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWFKYVGLNGAIVGMTTF
GESAPAEQLFEEYGFTVDNVVAKAKALL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 82
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68