Gene Information

Name : hemC (KP1_0163)
Accession : YP_002917139.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 167845 - 168801 bp
Length : 957 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGACGGTAACAAGCATGTTAGACAAAGTTTTGAAAATTGCCACACGGCAAAGCCCGCTTGCGCTATGGCAGGCGCAGTA
TGTTAAAGCGCGCCTGGAACAAGCGCATCCCGGACTGAAGGTCGAGCTGGTGCCGATGGTCACGCGCGGGGATGTCATCC
TTGATACTCCGCTGGCAAAGGTGGGGGGCAAAGGCTTATTTGTGAAAGAGTTAGAGCTCGCCATGCTCGAAGGGCGCGCC
GATATCGCCGTCCATTCGATGAAAGATGTGCCGGTGGAATTCCCGGAGGGCCTGGGGCTGGTGACTATCTGCGAGCGCGA
CGATCCGCGCGACGCGTTTGTCTCCAATCGCTATGCCTCGATTGACGAACTGCCGGCCGGCAGCGTCGTTGGCACGTCAA
GTTTACGCCGTCAGTGCCAGCTGGCCGCCACCCGTCCGGACCTGGCGATCCGCTCTCTGCGCGGTAACGTCGGTACCCGG
CTGAGTAAGCTGGATAACGGCGAGTACGACGCCATCATCCTCGCCGCCGCCGGCCTGAAGCGCCTGCAGCTGGAAGCGCG
TATTCGCCAGCCGCTGTCGCCTGAGCAATCTCTGCCGGCGGTCGGCCAGGGCGCGGTCGGCATCGAATGCCGTCTTGATG
ATGCATGGACCCGGGGGCTGTTAGCGCCTCTCAACCATACGGAAACGGCGGTGCGCGTGCGCGCCGAGCGGGCGATGAAC
ACCCGCCTCGAAGGCGGCTGCCAGGTGCCGATCGGCAGCTATGCGGAACTGAAGGACGGGGAACTGTGGCTGCGGGCGCT
GGTTGGCGCTCCGGATGGTTCACAGCTGGTGCGCGGCGAACGACGCGGGCCAGCGGAACAAGCGGAAGCCCTCGGCATCT
CGCTGGCGGAAGAGCTTCTGGATAATGGCGCCCGCGAGATTCTCGCGGCGGTTTATGATGGAGAAGCCCCGCGATGA

Protein sequence :
MTVTSMLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLKVELVPMVTRGDVILDTPLAKVGGKGLFVKELELAMLEGRA
DIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVSNRYASIDELPAGSVVGTSSLRRQCQLAATRPDLAIRSLRGNVGTR
LSKLDNGEYDAIILAAAGLKRLQLEARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTRGLLAPLNHTETAVRVRAERAMN
TRLEGGCQVPIGSYAELKDGELWLRALVGAPDGSQLVRGERRGPAEQAEALGISLAEELLDNGAREILAAVYDGEAPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-88 63
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-88 63