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Name : leuS (KP1_1630) Accession : YP_002918443.1 Strain : Klebsiella pneumoniae NTUH-K2044 Genome accession: NC_012731 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 1569531 - 1572137 bp Length : 2607 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : TTGAAAACAGGACCACTGGCTGCCATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCGAAAGTCCAGCTTCACTGGGA CGAAAATCGTACATTTGAAGTAACTGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCTTATCCTTCTG GTCGACTACACATGGGTCACGTGCGTAACTACACCATCGGCGACGTGATTGCCCGCTACCAGCGCATGCTGGGCAAAAAC GTCCTGCAGCCGATCGGCTGGGATGCGTTCGGTCTGCCGGCAGAAGGGGCGGCGGTGAAAAACAACACCGCGCCAGCGCC GTGGACCTACGACAACATCGCCTACATGAAAAACCAGCTCAAAATGCTGGGCTTCGGCTATGACTGGAGCCGCGAGCTGG CGACCTGCACCCCGGAATACTACCGCTGGGAGCAGAAGTTCTTCACCGAGCTGTACAAAAAAGGCCTGGTGTACAAAAAA ACCTCCGCAGTGAACTGGTGCCCGAATGACCAGACCGTGCTGGCCAACGAACAGGTTATCGACGGCTGCTGCTGGCGCTG CGATACCAAGGTCGAGCGTAAAGAGATCCCGCAGTGGTTTATTAAAATCACCGCCTACGCCGATGAACTGCTGAACGATC TGGATAAGCTGGACCACTGGCCGGACACCGTGAAGACCATGCAGCGCAACTGGATCGGCCGTTCGGAAGGGGTAGAAATC TCCTTTGACGTCAACGACTACGCTGACAAACTGACTGTCTACACCACCCGTCCGGACACCTTTATGGGTTGTACCTACCT GGCCGTCGCGGCGGGTCACCCGCTGGCGCAGCAGGCTGCGGCGAACAATCCGGCGCTGGCCGCCTTTATCGACGAGTGCC GCAATACCAAAGTGGCCGAAGCCGACATGGCGACGATGGAGAAAAAAGGCGTCGATACCGGCTTTAAAGCCATTCATCCG CTGACCGGTGAACAAATTCCGGTCTGGGCGGCAAACTTTGTGCTGATGGAATACGGCACCGGCGCGGTAATGGCCGTTCC GGGTCACGACCAGCGCGACTACGAGTTCGCCAGCAAGTACGGTCTGAACATTAAGCCGGTTATCCTCGCTGCCGACGGCT CTGAGCCGGATCTCTCCGAGCAGGCGCTGACCGAGAAAGGCGTCCTGTTTAACTCCGGCGAGTTCAGCGGTCTTGATTAT GAAGCGGGCTTCAACGCCATTGCCGACAAACTGACCGCCATGGGCGTGGGCGAGCGTAAAGTTAACTACCGTCTGCGCGA CTGGGGCGTATCCCGTCAGCGCTACTGGGGCGCGCCGATCCCGATGGTGACCCTGGAAGATGGCACCGTGCTGCCGACCC CGGAAGATCAGCTGCCGGTGATCCTGCCGGAAGACGTGGTCATGGACGGCATCACCAGCCCGATCAAAGCCGATCCTGAA TGGGCCAAGACCACCGTCAACGGCCAGCCGGCGCTGCGCGAAACCGACACCTTTGACACCTTTATGGAATCCTCCTGGTA CTATGCGCGCTACACCTGCCCGCAGTATCAGGAAGGAATGCTGGATTCGAAAGCGGCCAACTACTGGCTGCCGGTAGATA TCTACATCGGCGGTATCGAACACGCCATCATGCACCTGCTCTACTTCCGCTTCTTCCATAAGCTGATGCGCGACGCGGGC ATGGTGAACTCCGATGAGCCGGCGAAACAGCTGCTGTGCCAGGGCATGGTGCTGGCTGACGCGTTCTACTATGTGGGCGA AAACGGCGAACGTAACTGGGTTTCCCCGGTTGACGCCATCGTTGAGCGCGACGAAAAAGGCCGCATCGTGAAGGCCAAAG ACGCGGCGGGCCACGAGCTGGTGTACACCGGCATGAGCAAGATGTCCAAGTCGAAAAACAACGGCATCGACCCGCAGGTG ATGGTTGAGCGCTACGGCGCGGATACCGTGCGTCTGTTCATGATGTTTGCGTCCCCGGCGGATATGACCCTCGAGTGGCA GGAATCTGGCGTTGAAGGGGCGAACCGCTTCCTGAAACGCGTCTGGAAACTGGTCTACGAGCACACCACTAAAGGAGAGG TTGCGGCACTGAACGTGGCGGCTCTGAGCGAAGATCAGAAAGCGCTGCGTCGCGATATCCACAAAACCATCGCCAAAGTG ACCGATGACATCGGCCGTCGTCAGACCTTCAACACCGCCATCGCGGCAATCATGGAGCTGATGAACAAGCTGGCGAAAGC GCCGCAGGAAGATGAGCAGGATCGTGCGCTGATGCAGGAAGCTCTGCTGGCGGTGGTGCGTATGCTCAACCCGTTCACTC CGCACGCCAGCTTCACCCTGTGGCGTGAGCTGAACGGCGAAGGCGATATCGACAACGCGCCGTGGCCGGTAGCGGATGAG AGCGCGATGGTGGAAGACAGCACCCTCGTCGTCGTCCAGGTCAATGGCAAAGTTCGTGGTAAAATTACCGTTGCGGTAGA TGCAACTGAAGAGCAGGTTCGCGAGCGCGCCGGCCAGGAACATCTGGTGGCGAAATATCTCGACGGTAAAACCGTGCGTA AAGTGATTTACGTTCCGGGTAAACTGCTCAATCTGGTCGTTGGCTAA Protein sequence : MKTGPLAAMQEQYRPEEIESKVQLHWDENRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKN VLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKK TSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEI SFDVNDYADKLTVYTTRPDTFMGCTYLAVAAGHPLAQQAAANNPALAAFIDECRNTKVAEADMATMEKKGVDTGFKAIHP LTGEQIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSEQALTEKGVLFNSGEFSGLDY EAGFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPE WAKTTVNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAG MVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQV MVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTTKGEVAALNVAALSEDQKALRRDIHKTIAKV TDDIGRRQTFNTAIAAIMELMNKLAKAPQEDEQDRALMQEALLAVVRMLNPFTPHASFTLWRELNGEGDIDNAPWPVADE SAMVEDSTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGKTVRKVIYVPGKLLNLVVG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-149 | 42 |
