Gene Information

Name : ribD (KP1_1232)
Accession : YP_002918085.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : -
Position : 1191524 - 1192627 bp
Length : 1104 bp
Strand : +
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
ATGCAGGACGAAATGTACATGGCGCGTGCGCTGAAGCTTGCCGCGCGCGGTCGCTTTACTACCCATCCTAACCCTAACGT
CGGCTGCGTCATTGTGAAAGACGGCGAGATCGTCGGCGAGGGGTTTCACTATCGCGCCGGCGAGCCGCATGCTGAAGTGC
ACGCCCTGCGCATGGCTGGCGAAAAGGCGCGCGGCGCCACCGCCTACGTCACTCTTGAGCCCTGCAGCCACCATGGCCGT
ACGCCGCCATGCTGCGATGCGCTGATTGCCGCCGGCGTCAGCCGCGTGGTCGCCGCGATGCAGGATCCGAACCCGCAGGT
GGCGGGGCGCGGTTTGTATCGCCTGCAGCAGGCCGGCATTGAGGTCAGCCATGGGCTGATGATGAACGAAGCGGAAGCGC
TGAATAAGGGCTTTCTGAAGCGGATGCGCACCGGTTTTCCCTGGGTGCAGCTGAAGCTGGGCGCCTCGCTGGACGGCCGC
ACGGCGATGGCCAGCGGCGAAAGCCAGTGGATCACCTCCCCGCAGGCGCGACGCGACGTGCAGCGTCTACGCGCCCAGAG
CCATGCCATCCTGACCAGCAGCGCCACCGTGCTGGCGGACGATCCGGCGCTGACCGTGCGCTGGCAGGAGCTGAGCGCCG
ATACCCAGGCGCTTTATCCCGAAGAGAATTTGCGCCAGCCGCTGCGCGTCGTCATCGACAGCCAGAACCGCGTCACGCCT
GAGCATCGTATTGTGCAGCAGGCGGGGGAAACGCTGTTTGCCCGCCTGCGCGCCGATGAACGGCAGTGGCCGGAAAGCGC
CCGCACGCTGCTGGTTCCGGAGCATAACGGCCATCTCGATCTGGTGCTGCTGATGATGCTGCTTGGCAAACAGCAGATCA
ACAGCGTCTGGGTTGAGGCAGGGGCTACGCTTGCCGGGGCGCTGCTGCAGGCGGGTCTGGTCGACGAGCTTATCGTCTAT
ATTGCGCCTAAACTGTTAGGCAATGCGGCGCGTGGATTATGCGCGCTGCCGGGGCTTGAAGAGCTGAGCCAGGCCCCCCA
TTTTAAATTCAATGAGATACGTCAGGTTGGCCCGGATGTCTGCCTGCATTTAACCACTGCGTGA

Protein sequence :
MQDEMYMARALKLAARGRFTTHPNPNVGCVIVKDGEIVGEGFHYRAGEPHAEVHALRMAGEKARGATAYVTLEPCSHHGR
TPPCCDALIAAGVSRVVAAMQDPNPQVAGRGLYRLQQAGIEVSHGLMMNEAEALNKGFLKRMRTGFPWVQLKLGASLDGR
TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWQELSADTQALYPEENLRQPLRVVIDSQNRVTP
EHRIVQQAGETLFARLRADERQWPESARTLLVPEHNGHLDLVLLMMLLGKQQINSVWVEAGATLAGALLQAGLVDELIVY
IAPKLLGNAARGLCALPGLEELSQAPHFKFNEIRQVGPDVCLHLTTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 4e-56 48
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 4e-56 48