Gene Information

Name : RPR_04825 (RPR_04825)
Accession : YP_002916657.1
Strain : Rickettsia peacockii Rustic
Genome accession: NC_012730
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 824878 - 826155 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAAATATCAAATGGATTAGAGAAAATAAAGAATTGTTCGATGAAAAGCTTAGCCAAAGATTTATTGAACCTATGTC
TAGTAAAATTGCTATGCTCGACAGAGAGAAAAGAAAAATTACGAGTTTAATTCAAGAATTTCAGCATGCACGTAAGGTAA
AATCAAAGATTTTAGGTAATATGGCCTCTAAAAGCGGCGAAGAATTTGAAGGGTTACAAAGAGATGTCAAACATATAAAT
GAGAAGTTGGAAGCACTTGAACATGATCTAAATAATAATAACGAATTAAATGAACTATTAAATATGTTTCCTAATATTCC
GGACGAAGAAGTACCTTACGGAATGGATGAAAGTATGAATAAATTAGTTCGTACTTACGGAGAGACAAATCCAAATGCTT
TGAATAAACAGCATTTTGAACTAGGTATAAAATTAAATTTAATGGATTTTGAACAAACTGCTAAAATTTCTGGAACTAGA
TTTGTAACGTTAAAAGGTGATTTAGCAAAGCTAGAACGTGCTTTAATTAATTTTATGATTGATGTTCATACTAAAGAGTG
GGATTTCTTTGAGATATCACCTCCGGTATTAGTTCGAGATAATGCTATGTATAATGCAGGACAACTACCTAAATTTGCCG
AAGAGTCTTTTGCAACAACCAATGGTTACAGACTAATTCCAACCGCAGAAGTATCTTTAGTAAATATGGTCGCCGATACT
ATTATACCAAGAGAAAAATTACCGATACGTTATGTTGCTTACACCCCGTGCTTTAGATCAGAAGCAGGTAGTAGCGGTAG
AGATACAAGAGGTATGATTAGATTACATCAGTTCGGTAAAGTTGAGCTAGTATCTATTACTACCCCTGAAGAATCAACAA
ATGAGCATGAATATATAACTAATGCATCAGAGACTATTTTACAAAAACTGAATCTTCCTTATCGTGTTATGTTACTTTGC
ACCGGAGATATGGGATTTGCGGCAAAAAAAACCTATGATATAGAAGTATGGCTTCCGGGACAAAAGCAATATCGCGAAAT
TGCTAGCTGTTCTAATTGTGGAGATTTTCAAGCACGTAGAATGAAAGCAAGATATAAAGAATTCGGCAGTAACGAAACTA
CCTTAGTTCATACTTTAAATGCTTCAGGATTACCTATCGGAAGAACTATGGTTGCAATACTTGAAAATTATCAGAATGAA
GATGGATCAATAACTATACCGGATGTCTTGATAAATTACATGGGAGGATTACAAAAAATCATTGCCTATAGTGAATAA

Protein sequence :
MLNIKWIRENKELFDEKLSQRFIEPMSSKIAMLDREKRKITSLIQEFQHARKVKSKILGNMASKSGEEFEGLQRDVKHIN
EKLEALEHDLNNNNELNELLNMFPNIPDEEVPYGMDESMNKLVRTYGETNPNALNKQHFELGIKLNLMDFEQTAKISGTR
FVTLKGDLAKLERALINFMIDVHTKEWDFFEISPPVLVRDNAMYNAGQLPKFAEESFATTNGYRLIPTAEVSLVNMVADT
IIPREKLPIRYVAYTPCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESTNEHEYITNASETILQKLNLPYRVMLLC
TGDMGFAAKKTYDIEVWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTMVAILENYQNE
DGSITIPDVLINYMGGLQKIIAYSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-79 46