Gene Information

Name : leuS (ckrop_2092)
Accession : YP_002907332.1
Strain : Corynebacterium kroppenstedtii DSM 44385
Genome accession: NC_012704
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2411348 - 2414470 bp
Length : 3123 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACAAATCCGAGAGAAAAGAGCCCGAATGGGGGCCAGTCAACTGGTCATCCCACTACGTCAGTGTCCTCCTCCCACAA
TACTTCGTCAGGCTCTCTTTCTTCGCGGTCGAGTGCGTCGTCGGCGCATCACGACGAACCACGTTTCCGCTACACCGCCG
GGCTGGCTGCGGAGATCGAAAACGCCTGGCACGAGCGTTGGTCCGACGAGGGGACGTTCAACGCGCCCAACCCCACCGGG
GATTTAGCCCCCCGCGATGGAGGTTCGGATCTTCCCGACGATCGGATCTTTGTCCAAGATATGTTCCCCTATCCATCGGG
CGTCGGCCTGCACGTTGGCCACCCCTTGGGCTACATTGCGACGGACGTCTACGCACGTTTCCACCGCATGTTGGGCAAGA
ACGTGCTGCACACACTGGGATATGACGCCTACGGCCTCCCTGCGGAACAGTACGCGGTCCAGACAGGAACGCACCCGCGG
ACCACCACCGAGGCGAATATCGCAAACATGAAGCGCCAGCTGGGGCGCCTGGGTCTGGGGCATGACCCTCGTCGGTCATT
TGCTACGACTGACCAAGATTTCTACCGCTGGACCCAGTGGATTTTCCTCCAGATTTTCAACTCGTGGTTTGACCCCCAGG
CCAACGCAGCCCGGCCGGTCGCGGAATTGCGGGAAAAGCTGGCATCGGGCGCGGTCAATGTGACCTCCGGCCCCGGCTAC
CAGAGCGTTGATCCCGACACGGGTGCAGCAGTCGAAGCCGCTGAACAAGCCGGCAAGAGCTCCGCGGAAATATGGGAATC
GCTGGATGATGCTCAGCGTGAGCACGTCGTTGAAACCTTCCGTTTGGTCTATCGGTCCAGGTCAACGGTGAATTGGGCCC
CCGGGCTCGGCACGGTCTTGGCCAATGAAGAAGTCACGGCCGACGGCCGCTCGGAACGTGGCAATTTCCCCGTTTTCCGC
AAGAAACTGACCCAGTGGATGATGCGGATCACGCAGTACTCGGATCGTCTGCTCGACGATCTCGACCTGCTGGACTGGCC
CGACAAGGTGAAGTCCATGCAGCGCAACTGGATCGGCCGGTCCCGGGGTGCGGAAGTCACCTTCGCCATCCCGACGAACA
CCTCCAGCCACGACGCCGCACAGTGCCCCGTGTTCACCACCCGCCCCGACACCCTCTTCGGCGCGGAATACCTCGTCTTG
GCGCCAGAACATGAGCTTGTCGACGAGATCGTCGCAGATCAGTGGCCGGATCTCCGCGCCGAGCGCTCGCTCTCCGACGA
CGCCATCGACCGCTGGACCAGCGGCGCGGCCACCCCTGCCGAGGCGGTGAAGGAGTACCGCGCGTCCATCGTCGCGAAGT
CCGATTTGGAACGCCAAGAGAACAAGGAAAAAACCGGTGTCTTCCTGGGCGTGTACGCCACGAACCCGGTGAATGGCCGC
CGCATCCCCGTGTTCATCGCCGACTATGTCCTGTCCGGCTACGGCACGGGTGCGATCATGGCTGTTCCCGCGCACGATGA
GCGCGACTACGACTTCGCGCGCGTCTTCGAATTGCCCATCACCGAGGTCATTTCCGGCGGCGACGTCACCGTCGAGGCTT
TCACGGGCGCCGGCACCGCAGTGAACTCAGCCAACGACGACGGCCTAGACATCAACGGCCTCCACTTGGAGGACGCGAAA
GCACGCACCATCGATTGGCTCGCCCAGCGTGGCGTCGGCAAGGAAAAAATCCAGTACAAGCTGCGTGATTGGCTCTTCGC
TCGCCAGCGGTACTGGGGCGAGCCCTTCCCCGTTGTGTACGACGAGAACGACGTCGCTCACCCGCTCCCGGAGTCCATGT
TGCCCGTTGTGCTCCCGGATGTGGACGACTACCGGCCGGTATCCTTCGATCCCGATGACGCGGAATCGGAACCACACCCG
CCGCTGGCCAAGGCCAAGGACTGGGTCAATGTGGAGCTGGATTTGGGCGATGGCCCCAAGAAGTACCGACGCGATACGAA
CGTGATGCCGCAATGGGCGGGAAGTTCCTGGTACGAGCTCCGCTATGTGGATCCCACGAATCAGGACGCGCTCTGCGACC
CCGAGAATGAAAAGTACTGGATGGGCCCCACGGATCAGAAGAAATCCGGCGGCGTGGACCTGTATGTCGGCGGTGTCGAG
CACGCGGTGCTGCACCTGCTCTACTCCCGGTTCTGGCACAAGGTGCTGTTCGACCTCGGCTACGTGTCCTCCTGCGAGCC
GTACCATCGCCTCTTCAACCAGGGCTACATCCAGGCTTTCGCGTACACCGACGACCGCGGCGTGTACATCCCCGCCGCGG
AGGTTGTGGAGCGCGACGGTTCCTTCTGGTGGGTTCCCAGCGACGGGCGGAACATGGATGGTGTTCAGACCAATGAGCAC
GGCGAAATCCAGGTTCACCAGGAGTACGGAAAGATGGGCAAATCCCTGAAGAATGCCGTCTCCCCTGAGGACATTTGCGA
CAACTATGGTGCCGATACGCTGCGCATTTACGAAATGTCGATGGGTCCGCTGGATACGTCTCGCCCCTGGGCGACGAAGG
ACGTCGTTGGTTCGCAGCGCTTCTTGCAGCGTCTGTGGCGACTGGTGGTCGATGAATCCACCGGTGACCTCGTCGTCACG
GATGCGACCCCCACCGATGACGATCGCCGCGCCCTGCACCGCACGATTGTCGCAGTCCGCGAGGATTACGCCCAGCTGAT
GGATAACACTGCGGTGGCGAAACTCATTGAGTACGTCAACTATGTGACGAAAACGTATGCGGGCGGCGCTCCCCGCGAGA
TCGTCGAACCAGCTGTGCTGCTCGTTGCCCCGCTTGCCCCGCATATCGCGGAAGAGCTGTGGTCGCGGCTGGGTCACACT
GAGTCCTTGGCTCACGGCCCCTTCCCGACGTTCGAGGAGAAGTGGCTTGTCGACGACACCGTCGAGATTCCTGTTCAGGT
GCAGGGGAAAGTCCGCAGCCGTATTAATGTAGCGACGGATGCCTCGCGCGAAGATATTGAAGCTGCGGCACTTGATGATG
CCAAGGTGAAAGAGCACGTGGGCGATCATGAGATTAAGAAAGTGATCGTTGTCCCTGGCCGTATGGTCAACGTGGTGATC
TAG

Protein sequence :
MTNPREKSPNGGQSTGHPTTSVSSSHNTSSGSLSSRSSASSAHHDEPRFRYTAGLAAEIENAWHERWSDEGTFNAPNPTG
DLAPRDGGSDLPDDRIFVQDMFPYPSGVGLHVGHPLGYIATDVYARFHRMLGKNVLHTLGYDAYGLPAEQYAVQTGTHPR
TTTEANIANMKRQLGRLGLGHDPRRSFATTDQDFYRWTQWIFLQIFNSWFDPQANAARPVAELREKLASGAVNVTSGPGY
QSVDPDTGAAVEAAEQAGKSSAEIWESLDDAQREHVVETFRLVYRSRSTVNWAPGLGTVLANEEVTADGRSERGNFPVFR
KKLTQWMMRITQYSDRLLDDLDLLDWPDKVKSMQRNWIGRSRGAEVTFAIPTNTSSHDAAQCPVFTTRPDTLFGAEYLVL
APEHELVDEIVADQWPDLRAERSLSDDAIDRWTSGAATPAEAVKEYRASIVAKSDLERQENKEKTGVFLGVYATNPVNGR
RIPVFIADYVLSGYGTGAIMAVPAHDERDYDFARVFELPITEVISGGDVTVEAFTGAGTAVNSANDDGLDINGLHLEDAK
ARTIDWLAQRGVGKEKIQYKLRDWLFARQRYWGEPFPVVYDENDVAHPLPESMLPVVLPDVDDYRPVSFDPDDAESEPHP
PLAKAKDWVNVELDLGDGPKKYRRDTNVMPQWAGSSWYELRYVDPTNQDALCDPENEKYWMGPTDQKKSGGVDLYVGGVE
HAVLHLLYSRFWHKVLFDLGYVSSCEPYHRLFNQGYIQAFAYTDDRGVYIPAAEVVERDGSFWWVPSDGRNMDGVQTNEH
GEIQVHQEYGKMGKSLKNAVSPEDICDNYGADTLRIYEMSMGPLDTSRPWATKDVVGSQRFLQRLWRLVVDESTGDLVVT
DATPTDDDRRALHRTIVAVREDYAQLMDNTAVAKLIEYVNYVTKTYAGGAPREIVEPAVLLVAPLAPHIAEELWSRLGHT
ESLAHGPFPTFEEKWLVDDTVEIPVQVQGKVRSRINVATDASREDIEAAALDDAKVKEHVGDHEIKKVIVVPGRMVNVVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-146 47