Gene Information

Name : GBP346_A0773 (GBP346_A0773)
Accession : YP_002895497.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 731092 - 731901 bp
Length : 810 bp
Strand : +
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence : 
GTGAGCAACGGGCGCGCGTGGCGCAAGCCGCACATTGTAGAGAAAACGGCGCGCGAGCAGCGCCGAAATCGCCCGAAGGT
CCGTTCCCGCGCGCGGCGGCGCTACAATGTCCGCCATCTCGAACGCATGCGACGGACGTTTTTCAGGATGCGGATATTGC
TGGTTGAAGACGATCGGATGATCGCCGAAGGCGTGCGCAAGGCGCTGAAGGCCGACGGCTGCGCGGTCGACTGGGTGCAG
GACGGCGACGCGGCGCTCACCGCGCTCGGCGGCGAGGCGTACGATCTGCTGCTGCTCGATCTCGGGCTGCCCAAGCGCGA
CGGCATCGACGTGCTGCGCACGCTGCGCGCGCGCGGGCTCGCGCTGCCGGTGCTGATCCTCACCGCGCGCGATGCGGTCG
CCGATCGCGTGAAGGGCCTCGACGCGGGCGCCGACGACTATCTCGTCAAGCCGTTCGATCTCGACGAGCTCGCCGCGCGG
ATGCGCGCGCTGATCCGCCGCCAGTCGGGGCGCAGCGAATCGATGATCCGGCACGGCGCGCTGACGCTCGATCCGGCGTC
GCATCAGGTGACGCTCGACGGGGCGCCCGTCGCGCTGTCGGCGCGCGAGTTCGCGCTGCTCGAAGCGCTGCTCGCGCGTC
CGGGCGCGGTGCTGTCGAAGAGCCAGCTCGAGGAGAAGATGTACGGCTGGGGCGAGGAGATCGGCAGCAACACCGTCGAG
GTCTATATCCACGCGCTGCGCAAGAAGCTCGGCTCGGACCTGATCCGCAACGTCCGCGGCCTCGGCTACATGGTCGTGAA
GGAAGCGTAG

Protein sequence : 
MSNGRAWRKPHIVEKTAREQRRNRPKVRSRARRRYNVRHLERMRRTFFRMRILLVEDDRMIAEGVRKALKADGCAVDWVQ
DGDAALTALGGEAYDLLLLDLGLPKRDGIDVLRTLRARGLALPVLILTARDAVADRVKGLDAGADDYLVKPFDLDELAAR
MRALIRRQSGRSESMIRHGALTLDPASHQVTLDGAPVALSAREFALLEALLARPGAVLSKSQLEEKMYGWGEEIGSNTVE
VYIHALRKKLGSDLIRNVRGLGYMVVKEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 4e-35 51
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-21 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 3e-21 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GBP346_A0773 YP_002895497.1 DNA-binding response regulator BAC0487 Protein 2e-30 48
GBP346_A0773 YP_002895497.1 DNA-binding response regulator BAC0083 Protein 8e-23 45
GBP346_A0773 YP_002895497.1 DNA-binding response regulator BAC0197 Protein 3e-26 45
GBP346_A0773 YP_002895497.1 DNA-binding response regulator BAC0638 Protein 3e-22 44
GBP346_A0773 YP_002895497.1 DNA-binding response regulator NC_002516.2.879194.p Protein 1e-24 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GBP346_A0773 YP_002895497.1 DNA-binding response regulator VFG0473 Protein 2e-32 48
GBP346_A0773 YP_002895497.1 DNA-binding response regulator VFG1390 Protein 6e-32 47
GBP346_A0773 YP_002895497.1 DNA-binding response regulator VFG0596 Protein 5e-22 42
GBP346_A0773 YP_002895497.1 DNA-binding response regulator VFG1389 Protein 1e-21 41