Gene Information

Name : cadR (GBP346_A4120)
Accession : YP_002898773.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Resistance
Product : Cd(II)/Pb(II)-responsive transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG0789
EC number : -
Position : 3948221 - 3948652 bp
Length : 432 bp
Strand : +
Note : identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02047

DNA sequence :
ATGAAGATCGGCGAACTGGCGAAAGCGGCGCGGTGCACGCCGGAAACGATTCGCTTCTATGAAAAAGAGGGGCTGATGCC
CGACGCGGAACGGACCGATTCCAACTACCGCCACTACACCGACGCGCACGTCGAGCGGCTGCGCTTCATCCGCAACTGCC
GCGCGCTCGACATGACGCACGATGAAATCCGCGCACTGCTGCGCTTCACCGACGACCCGGCGGACCGCTGCGATTCGGTC
AACGCGCTGCTCGACGAACACATCGGCCACGTCAACACGCGGCTTGCCGAACTGCAGCATTTGCGCATGCAATTGATCGA
ATTGCGCGAACGGTGCCAGGGCGAGCACGCAGTCGAGGATTGCGGAATCGTGCATGGCCTCTCGACGATGGAAACGCCGG
ACATGCCCGGCAAACGCTCGCACGTCGGCTGA

Protein sequence :
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRHYTDAHVERLRFIRNCRALDMTHDEIRALLRFTDDPADRCDSV
NALLDEHIGHVNTRLAELQHLRMQLIELRERCQGEHAVEDCGIVHGLSTMETPDMPGKRSHVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadR ACS32041.1 MerR family transcriptional regulator Not tested AbaR5 Protein 3e-33 50
ACICU_00234 YP_001844893.1 transcriptional regulator Not tested AbaR20 Protein 1e-33 50
cadR ADZ05769.1 MerR family transcriptional regulator Not tested AbaR11 Protein 2e-33 50
pbrR CAJ77094.1 Transcriptional regulator Not tested AbaR1 Protein 7e-34 50
cadR AGK36653.1 MerR family transcriptional regulator Not tested AbaR26 Protein 7e-34 50
cadR ACN81029.1 MerR family transcriptional regulator Not tested AbaR5 Protein 1e-33 50
pbrR CAJ77021.1 transcription regulator Not tested AbaR1 Protein 2e-33 50
ORF C98 AAN62191.1 putative transcriptional regulator Not tested PAGI-2(C) Protein 6e-31 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadR YP_002898773.1 Cd(II)/Pb(II)-responsive transcriptional regulator BAC0058 Protein 2e-38 59
cadR YP_002898773.1 Cd(II)/Pb(II)-responsive transcriptional regulator BAC0301 Protein 1e-31 53