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Name : GBP346_A4109 (GBP346_A4109) Accession : YP_002898761.1 Strain : Burkholderia pseudomallei MSHR346 Genome accession: NC_012695 Putative virulence/resistance : Virulence Product : acetaldehyde dehydrogenase 2 (acetaldehyde dehydrogenaseii) (acdh-ii) Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.3 Position : 3934850 - 3936469 bp Length : 1620 bp Strand : + Note : identified by match to protein family HMM PF00171 DNA sequence : ATGCACCGCGGCGCGGCGTGCTGGCACGGTTTTGGCGTAACGAACGGCGTCGCGCACGTCGCGCGGCGCATCACCGATAC CGACATGCGAGGAGCAACGATGAATCACGCGGACATGCAACATCTGAACATCGAATTCCCGTACCGCAAGCAGTACGGGA ATTTCATCGGCGGCGAATGGGTCGCCCCGGTCGGCGGCGAGTATTTCGACAACGTCTCGCCCGTCACCGGCCGGCCGTTC ACCGCGATCCCTCGCTCGCGCGAAGCCGACGTCGAACTCGCGCTCGACGCCGCTCACGCGGCCAAGGCGGGCTGGGCCGC GAAGAGCGCGGCCGAGCGCGCGAACGTGCTGCTGAGGATCGCCGACCGGATGGAGGCGAACCTCACGCGCCTCGCCGTCG CCGAGACGATCGACAACGGCAAGCCGCTGCGCGAAACCACCGCGGCCGACGTGCCGCTCGCGATCGACCACTTCCGCTAC TTCGCGGGCTGCATCCGCGCGCAGGAAGGCTCGATCGCCGATATCGGCGGCGACATGGTGGCCTACCACTTCCACGAGCC GCTCGGCGTCGTCGGCCAGATCATCCCGTGGAACTTCCCGCTGCTGATGGCCGCGTGGAAGCTCGCGCCGGCGCTCGCGG CCGGCAACTGCGTCGTGCTCAAGCCGGCCGAGCAGACGCCCGCGTCGATCCTCGTGTTCGCCGAGCTGATCCAGGATCTG CTGCCGCCCGGCGTGCTCAACATCGTCAACGGCTTCGGCCTCGAGGCCGGCAAGCCGCTCGCGTCAAGCAAGCGGATCGC GAAGATCGCGTTCACGGGCGAGACGTCGACGGGCCGCCTCATCATGCAGTACGCGAGCGAGAACCTGATTCCCGTCACGC TCGAGCTGGGCGGCAAGAGCCCGAATATTTTCTTCGCCGACGTGATGGATCGCGACGACAGCTACTTCGACAAGGCGCTC GAAGGCTTCGCGATGTTCGCGCTGAACCAGGGCGAAGTCTGCACGTGCCCATCGCGCGCGCTCGTCGAGGAGAGCATCTA CGATCGCTTCATCGAACGCGCGCTCAAGCGCGTCGAGGCGATCAAGCAGGGCCATCCGCTCGATTCGCAGACGATGATCG GCGCGCAGGCGTCGGCCGAGCAGCTCGAGAAGATCCTGTCGTACATCGACATCGGCCGCGGCGAAGGCGCGCAATGCCTG ACGGGCGGCGAGCGCAACGTGCTCGGCGGCGAGCTCGCCGAAGGCTATTACGTGAAGCCGACCGTGTTCCGCGGCCACAA CAAGATGCGCATCTTCCAGGAAGAAATCTTCGGGCCGGTGCTCGCGGTGACGACGTTCAAGACCGAGGAGGAAGCGCTCG AGATCGCGAACGACACGCTGTACGGCCTGGGCGCCGGCGTCTGGACGCGCGACGGCAACCGCGCGTACCGCTTCGGCCGC GGCATCCAGGCGGGCCGCGTGTGGACGAACTGCTATCACGCGTATCCGGCGCACGCGGCGTTCGGCGGCTACAAGCAATC CGGCATCGGCCGCGAGACGCACAAGATGATGCTCGACCACTACCAGCAGACGAAGAACCTGCTCGTCAGCTACAGCGAAA AGCCGCTCGGGTTCTTCTGA Protein sequence : MHRGAACWHGFGVTNGVAHVARRITDTDMRGATMNHADMQHLNIEFPYRKQYGNFIGGEWVAPVGGEYFDNVSPVTGRPF TAIPRSREADVELALDAAHAAKAGWAAKSAAERANVLLRIADRMEANLTRLAVAETIDNGKPLRETTAADVPLAIDHFRY FAGCIRAQEGSIADIGGDMVAYHFHEPLGVVGQIIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPASILVFAELIQDL LPPGVLNIVNGFGLEAGKPLASSKRIAKIAFTGETSTGRLIMQYASENLIPVTLELGGKSPNIFFADVMDRDDSYFDKAL EGFAMFALNQGEVCTCPSRALVEESIYDRFIERALKRVEAIKQGHPLDSQTMIGAQASAEQLEKILSYIDIGRGEGAQCL TGGERNVLGGELAEGYYVKPTVFRGHNKMRIFQEEIFGPVLAVTTFKTEEEALEIANDTLYGLGAGVWTRDGNRAYRFGR GIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLDHYQQTKNLLVSYSEKPLGFF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 9e-132 | 64 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-137 | 64 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-137 | 64 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-137 | 64 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-136 | 64 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 1e-58 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| GBP346_A4109 | YP_002898761.1 | acetaldehyde dehydrogenase 2 (acetaldehyde dehydrogenaseii) (acdh-ii) | VFG0082 | Protein | 4e-132 | 64 |
