Gene Information

Name : trpE (GBP346_A3730)
Accession : YP_002898397.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Unknown
Product : anthranilate synthase component I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : 4.1.3.27
Position : 3601990 - 3603558 bp
Length : 1569 bp
Strand : +
Note : with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine

DNA sequence :
GTGCTGCGGGCGCGAGCGCAGCGCCACGCGAAACCCGGCGCGCTGCGCCGATCGTCCCGACGACAGGACCGGAACATGAC
TGAACTCGAATTCCAATCGCTTGCCAACGAGGGCTACAACCGCATTCCGCTCATCGCCGAAGCGCTGGCCGACCTCGAAA
CGCCGCTTTCACTGTATCTGAAGCTCGCGCAGCCCGAACGCGGCGGCGCCAACTCGTTCCTGCTCGAATCGGTGGTGGGC
GGCGAGCGCTTCGGACGCTATTCGTTCATCGGCCTGCCCGCGCATACGCTGGTGCGCACGAAGAACGGCGTGTCGGAGGT
CGTGACGGACGGCCAGGTCACCGAGACCCACGACGGCGACCCGTTCGCGTTCATCGCGACATTCCAGAGCCGCTTCAAGG
TCGCGCAGCGCCCCGGCCTGCCGCGCTTCTGCGGCGGCCTCGCCGGCTATTTCGGCTACGACGCGGTGCGCTACATCGAG
AAGAAGCTCGCGCACACCGCGCCGCGCGACGATCTCGGCCTGCCCGACATCCAGTTGCTGCTGACCGAGGAAGTCGCCGT
GATCGACAACCTCGCCGGCAAGCTCTACCTGATCGTCTATGCCGATCCGACGAAGCCCGAGGCGTACACGAAAGCCAAGC
AACGGCTGCGCGAGCTCAAGCAGCGGCTGCGCGCGAGCGTCGTGCCGCCCGTCACGTCGGCGAGCGTGCGCACCGAGATC
TATCGCGAATTCAAGAAGGATGACTATCTGGCCGCCGTGCGCACGGCGAAGGAATACATCGCGGCGGGCGAGCTGATGCA
GATCCAGGTCGGCCAGCGCCTGACGAAGCCGTATCGCGACAATCCGCTGTCGCTGTACCGCGCGCTGCGCTCGCTGAACC
CGTCGCCATACATGTATTACTACAATTTCGGCGAATTCCATGTCGTCGGCGCTTCGCCGGAGATTCTCGTGCGTCAGGAG
AAGCGCGGCGACGACCAGATCGTGACGATCCGCCCGCTTGCCGGCACGCGGCCGCGGGGCAACACGCCCGAGCGCGACGC
CGAGCTCGCGACCGAACTGCTTAACGATCCGAAGGAAATCGCCGAGCACGTGATGCTGATCGACCTCGCGCGCAACGACG
TCGGCCGCATCGCGGAAATCGGCTCGGTCCACGTGACCGACAAGATGGTGATCGAGAAATACTCGCACGTGCAGCACATC
GTGAGTTCGGTCGAGGGCAAGCTGAAGCCCGGCGTGACGAACTACGACGTGCTGCGCGCGACGTTCCCGGCGGGCACGCT
GTCCGGCGCGCCGAAAGTCCGCGCGATGGAGCTGATCGACGAGCTCGAGCCGATCAAGCGCGGGCTGTACGGCGGCGCGG
TCGGCTACCTGTCGTTCTCGGGCGAGATGGATCTCGCGATCGCGATCCGCACGGGCCTCATCCACAACGGCAATCTGTAC
GTGCAGGCGGCGGCGGGCATCGTCGCCGACTCGGTGCCCGAATCCGAATGGCAGGAGACCGAGAACAAGGCGCGCGCGGT
GCTGCGCGCGGCCGAACAGGTGCAAGACGGCCTCGATTCCGATTTCTGA

Protein sequence :
MLRARAQRHAKPGALRRSSRRQDRNMTELEFQSLANEGYNRIPLIAEALADLETPLSLYLKLAQPERGGANSFLLESVVG
GERFGRYSFIGLPAHTLVRTKNGVSEVVTDGQVTETHDGDPFAFIATFQSRFKVAQRPGLPRFCGGLAGYFGYDAVRYIE
KKLAHTAPRDDLGLPDIQLLLTEEVAVIDNLAGKLYLIVYADPTKPEAYTKAKQRLRELKQRLRASVVPPVTSASVRTEI
YREFKKDDYLAAVRTAKEYIAAGELMQIQVGQRLTKPYRDNPLSLYRALRSLNPSPYMYYYNFGEFHVVGASPEILVRQE
KRGDDQIVTIRPLAGTRPRGNTPERDAELATELLNDPKEIAEHVMLIDLARNDVGRIAEIGSVHVTDKMVIEKYSHVQHI
VSSVEGKLKPGVTNYDVLRATFPAGTLSGAPKVRAMELIDELEPIKRGLYGGAVGYLSFSGEMDLAIAIRTGLIHNGNLY
VQAAAGIVADSVPESEWQETENKARAVLRAAEQVQDGLDSDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00338 YP_008207803.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR25 Protein 4e-111 51
BJAB0868_00342 YP_008211668.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR26 Protein 4e-111 51