Gene Information

Name : tkt (GBP346_A3612)
Accession : YP_002898285.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3487883 - 3489955 bp
Length : 2073 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCCGCCCGTGCCCCGTTTTCTCGACTCGTTCTCCGGACTCGACATGACGACTTCGTCTCCCGCCTCCACCACTCTGAT
GGCCAACGCGATCCGCGCGCTCGCGATGGACGCCGTCCAGCAAGCGAACTCCGGCCACCCCGGCATGCCGATGGGCATGG
CCGAGATCGGCGTCGCGCTGTGGTCGCGCCACCTGAAGCACAACCCGACGAACCCGCATTGGGCCGACCGCGACCGCTTC
GTGCTGTCGAACGGCCACGGCTCGATGCTGCTGTACTCGCTGCTGCACCTGACGGGCTACGATCTGCCGATCGAAGAGCT
GAAGAATTTCCGGCAATTGCATTCGAAGACGCCGGGCCACCCGGAATACGGGATCACGCCGGGCGTCGAGACGACGACGG
GCCCGCTCGGCCAGGGCCTCGCGAACGCGGTCGGCATGGCGCTCGGCGAGGCGCTGCTCGCCGCCGAGTTCAACCGCGAC
GACGCGAAGATCGTCGATCATCACACGTACGTGTTCGTCGGCGACGGCTGCCTGATGGAGGGCATCTCGCACGAAGCGTG
CTCGCTCGCGGGCACGCTCAAGCTCAACAAGCTGATCGCGTTCTACGACGACAACGGGATCTCGATCGACGGCGACGTCG
TCAACTGGTTCCACGACGACACGCCGAAGCGCTTCGAGGCGTACGGCTGGAACGTGATTCCGAACGTGAACGGCCACGAC
GTCGACGCGGTCGATGCCGCGATCGCGAAGGCGAAGAGCGCGGACAAGCCGACGCTCATCTGCTGCAAGACGGTGATCGG
CAAGGGCGCGGCGACGAAGGCGGGCGGCCACGACGTGCACGGCGCGGCGCTCGGCGCGGAGGAAATCGCGAAGACGCGCG
ACGCGCTCGGCTGGAAGTGGGCGCCGTTCGTGATTCCGCAGGAAGTCTACGCGGCGTGGGACGCGAAGGAAGCGGGCAAG
CGCCGCGAAGGCGACTGGAACGCGGCGTTCGCGCAGTACCGCGCGAAGTACCCGGCCGAGGCCGCCGAATTCGAGCGCCG
CATGGCGGGCAAGCTGCCGGCCGACTGGGCCGAGAAGGCCGCGGCGATCGTCGCCGGCGCGAACGAGCGCGGCGAGACGG
TCGCGACGCGCAAGGCGTCGCAGCAGACGATCGAGGGCCTTGCCGCCGTGCTGCCCGAGCTGCTCGGCGGCTCGGCCGAC
CTGACGGGCTCGAACCTCACGAACTGGAAGGCGTCGAAGGCGGTGCGCGCGAATGCGCACGGCGCGGGCATCCAGTGGGG
CAACCACATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCCGCGATCAACGGCCTCGTGCTGCACGGCGGCTACAAGC
CGTTCGGCGGCACGTTCCTCACGTTCTCCGACTACAGCCGCAACGCGCTGCGCGTCGCCGCGCTGATGAAGGTGCCGTCG
ATCTTCGTGTTCACGCACGATTCGATCGGCCTCGGCGAAGACGGGCCGACGCACCAGTCGGTCGAGCACGTCGCGAGCCT
GCGGCTGATTCCGAACCTCGACGTCTGGCGCCCGGCCGACACGGTCGAGACGGCGGTCGCGTGGACCCACGCGGTCTCGC
ACCAGCACCCGTCGTGCCTGGTCTTCAGCCGCCAGAACCTCGCGTTCAACGCGCGCACCGACGCGCAGCTCGCGAACATC
GAGAAGGGCGGCTACGTGCTGCGCGACTGGGACGAAGAGATCGTCGCGCGCAAGATCATCCTGATCGCGACGGGCTCGGA
AGTGGAGCTCGCGATGAAGGCGGTCGAGCCGCTCGCGCAGCAGGGGATCGCCGCGCGCGTCGTGTCGATGCCGTCGACCG
ACGTGTTCGACCGGCAGGACGCCGAGTACCGCGAGCGCGTGCTGCCGCACGGCGTGCGCCGCGTCGCGATCGAAGCGGGC
GTCACCGATTTCTGGCGCAAGTACGTGGGCCTCGAAGGCGGCGTGGTCGGCATCGACACGTTCGGCGAGTCGGCTCCGGC
TGGCGTGTTGTTCAAGCATTTCGGCTTCACGATCGAGCACGTGGTCGAAACGGCGAAGGCGGTGCTCGCGTAA

Protein sequence :
MPPVPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALLAAEFNRD
DAKIVDHHTYVFVGDGCLMEGISHEACSLAGTLKLNKLIAFYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAVDAAIAKAKSADKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRDALGWKWAPFVIPQEVYAAWDAKEAGK
RREGDWNAAFAQYRAKYPAEAAEFERRMAGKLPADWAEKAAAIVAGANERGETVATRKASQQTIEGLAAVLPELLGGSAD
LTGSNLTNWKASKAVRANAHGAGIQWGNHINYGVREFGMSAAINGLVLHGGYKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSVEHVASLRLIPNLDVWRPADTVETAVAWTHAVSHQHPSCLVFSRQNLAFNARTDAQLANI
EKGGYVLRDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTDVFDRQDAEYRERVLPHGVRRVAIEAG
VTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKHFGFTIEHVVETAKAVLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 64
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 60