Gene Information

Name : serS (GBP346_A3177)
Accession : YP_002897853.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 3071338 - 3072639 bp
Length : 1302 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGACATCCAGTTGCTGCGCAAAGACCTCGACGGCGTCGCGAAACGCCTCGCCGATCGCGGCTACCCCCTCGACGT
CGCCGCGTTCTCCGCGCTCGAAGCGGAACGCCGGGCGATCCAGACCCGCACCGAAGAACTGCAGGCGCGCCGCAACAGCC
TGTCGAAGCAGATCGGCGCGATGAAGGGGCGGGGCGAGGACACGTCGGCGGTGATGGCCGAGGTGGGCGGCATCGGCGAT
GAGATGAAGGCCTCGGCGGTGAAGCTCGACGAGATTCAGGCGCGCCTGTCCGAGCTGATGCTGGAAATGCCGAACGTGCC
GCACGAGAGCGTGCCCGTCGGCCGCGACGAGACGGAGAACGTCGAAGTGCGCCGCTGGGGCGCGCCGCGCCAGTTCGATT
TCGACGTGAAGGACCACGTCGATGTGGGCACGCCGCTCGGCCTCGATTTCGAGACGGGCGCGAAGCTCTCCGGCGCGCGC
TTCACGGTGCTGCGCGGGCCGATCGCGCGCCTGCACCGCGCGCTCGCGCAGTTCATGCTGGACACGCACACGCAGCAGCA
CGGCTACAGCGAGACGTACACGCCTTACATCGTGAATCCGGACGTGCTGTACGGCACGGGCCAGTTGCCGAAGTTCGCGG
AGGACATGTTCCGCGTCGAGAAGGGCGGCGCGGAGAACACGGTCACGCAATACCTGATCTCGACCTCGGAGATTTCGCTG
ACGAACACGGTGCGCGATTCGATCGTCGAAGCGTCCGCGCTGCCGATCAAGCTGACCGCGCATTCGCCGTGCTTCCGCTC
GGAGGCGGGCTCGTACGGCCGCGACACGCGCGGGATGATCCGCCAGCACCAGTTCGACAAGGTCGAGATGGTGCAGATCG
TCGCGCCGGAAGCATCGTACGCGGCGCTCGACGAGATGGTCGGCCACGCGGAGGCAATCCTGCAGAAGCTCGAACTGCCG
TACCGCGTGGTCGCGCTATGCACGGGCGACATGGGTTTCTCGGCGGCGAAGACGTTCGACCTCGAGGTGTGGCTGCCCGC
GCAGAACACGTATCGGGAGATTTCGAGCTGCTCGAATACCGAATCGTTCCAGGCGCGCCGCATGCAGGCGCGGTTCCGCA
ACGCGCAGGGCAAGCCCGAGCTCGTGCATACGCTGAACGGCTCGGGCCTCGCGGTCGGCCGCACGCTCGTCGCGGTGCTG
GAGAACTACCAGAACGCCGACGGCTCGGTGACGGTGCCCGTCGCGTTGCGGCCTTACATGGGCGGCGTCGAGCGGATCGA
CGCGCCTTCGAGCGCGGCCTGA

Protein sequence :
MLDIQLLRKDLDGVAKRLADRGYPLDVAAFSALEAERRAIQTRTEELQARRNSLSKQIGAMKGRGEDTSAVMAEVGGIGD
EMKASAVKLDEIQARLSELMLEMPNVPHESVPVGRDETENVEVRRWGAPRQFDFDVKDHVDVGTPLGLDFETGAKLSGAR
FTVLRGPIARLHRALAQFMLDTHTQQHGYSETYTPYIVNPDVLYGTGQLPKFAEDMFRVEKGGAENTVTQYLISTSEISL
TNTVRDSIVEASALPIKLTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVAPEASYAALDEMVGHAEAILQKLELP
YRVVALCTGDMGFSAAKTFDLEVWLPAQNTYREISSCSNTESFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVAVL
ENYQNADGSVTVPVALRPYMGGVERIDAPSSAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-112 58