Gene Information

Name : folA (GBP346_A3022)
Accession : YP_002897706.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 2938103 - 2938606 bp
Length : 504 bp
Strand : +
Note : identified by match to protein family HMM PF00186

DNA sequence :
ATGACGACGCTGACCTTGATCGTCGCGCGCGCCCGCAACGGCGTGATCGGCCGCGACAACCGACTTCCGTGGAAACTCCC
CGAGGACCTCGCGTTCTTCAAGCGCACGACGATGGGCGCGCCGATCGTGATGGGCCGCAAGACGCACGAATCGATCGGCC
GGCCGCTGCCGGGGCGCCGCAACATCGTCGTCACGCGCGACGCCGCGCGCCGCTTCGACGGCTGCGACACAGTCACCTCG
CTCGAGGACGCGCTCGCGCTCGCCGCGCGCGACGGCGCGGCCGAAGCGTTCCTGATCGGCGGCGCGCAACTGTACGAGGA
AGGCCTGCGCCACGCGGACAAGCTGATCGTCACCGAAATCGATCAGGATTTCGAAGGCGACGCGTCGTTCCCCGCGCCCG
ATCCCGCGCAATGGGAAGCCGTGTCGCGCGACACGCACCGCGCGGCGCAGCCCAACGATTTCACGTACGCGTTCGTCGTC
TATCGCCGCAGGCGCGCCGGCTGA

Protein sequence :
MTTLTLIVARARNGVIGRDNRLPWKLPEDLAFFKRTTMGAPIVMGRKTHESIGRPLPGRRNIVVTRDAARRFDGCDTVTS
LEDALALAARDGAAEAFLIGGAQLYEEGLRHADKLIVTEIDQDFEGDASFPAPDPAQWEAVSRDTHRAAQPNDFTYAFVV
YRRRRAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 1e-22 43