Gene Information

Name : alr (GBP346_A2583)
Accession : YP_002897280.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 2520981 - 2522051 bp
Length : 1071 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCCGCGCCCGATTTCCGCCACGATCCACACCGCAGCTCTCGCGAACAACCTCTCCGTCGTGCGCCGCCACGCCGCCCA
GTCGAAGGTCTGGGCGATCGTCAAGGCGAACGCGTACGGGCACGGTCTCGCGCGCGTCTTTCCCGGGCTGCGCGGCACCG
ACGGCTTCGGCCTGCTCGACCTCGACGAGGCCGTGAAGCTGCGCGAACTGGGCTGGGCGGGGCCGATCCTGCTGCTCGAG
GGCTTCTTCCGGTCGACCGACATCGACGTGATCGACCGCTACAGCCTGACGACCGCGGTGCACAACGACGAGCAGATGCG
CATGCTCGAGACCGCGCGGCTGTCGAAGCCCGTGAACGTCCAGCTGAAGATGAACAGCGGCATGAACCGGCTCGGCTACA
CGCCCGAGAAGTACCGGGCTGCCTGGGAGCGCGCGCGCGCATGCCCGGGCATCGGCCAGATCACGTTGATGACCCATTTT
TCGGACGCCGACGGCGAACGCGGCGTGGCCGAGCAGATGGCGACGTTCGAGCGCGGCGCGCAAGGCATCGCCGGCGCGCG
CAGCTTCGCGAACTCGGCCGCCGTGCTCTGGCACCCGTCGGCGCACTTCGACTGGGTGCGGCCCGGCATCATGCTGTACG
GCGCGTCGCCGTCCGGCCGTGCGGCGGACATCGCCGACCGGGGCCTGAAGCCGACGATGACGCTCGCCTCCGAGCTGATC
GCCGTGCAGACGCTCGCGAAAGGGCAGGCGGTCGGCTACGGATCGATGTTCGTCGCCGAGGACACGATGCGCATCGGCGT
CGTCGCGTGCGGCTATGCGGACGGCTATCCGCGGATCGCGCCCGAGGGCACGCCCGTCGTCGTCGACGGCGTGCGCACGC
GGATCGTCGGCCGCGTGTCGATGGACATGCTGACCGTCGATCTCACGCCCGTGCCGCAGGCGGGCGTCGGCGCGCGCGTC
GAGCTGTGGGGCGAGACGCTGCCGATCGACGACGTCGCAGCCCGCTGCATGACGGTCGGCTACGAGCTGATGTGCGCGGT
CGCGCCGCGCGTGCCCGTGCGTGCCGAGTAA

Protein sequence :
MPRPISATIHTAALANNLSVVRRHAAQSKVWAIVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLE
GFFRSTDIDVIDRYSLTTAVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYTPEKYRAAWERARACPGIGQITLMTHF
SDADGERGVAEQMATFERGAQGIAGARSFANSAAVLWHPSAHFDWVRPGIMLYGASPSGRAADIADRGLKPTMTLASELI
AVQTLAKGQAVGYGSMFVAEDTMRIGVVACGYADGYPRIAPEGTPVVVDGVRTRIVGRVSMDMLTVDLTPVPQAGVGARV
ELWGETLPIDDVAARCMTVGYELMCAVAPRVPVRAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 2e-102 59