Gene Information

Name : thiC (GBP346_A1419)
Accession : YP_002896133.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1371008 - 1372939 bp
Length : 1932 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCCAACCCCAAGTTCCTGTCGGCCGACGCCCGCGTCGACGCCGCCGCCGTCGCCCCGCTGCCGAATTCGCGCAA
GGTCTACGTGACGGGCTCGCAACCCGACATCCGCGTGCCGATGCGTGAGATCACGCAGGCCGATACGCCGACGAGCTTCG
GCGGCGAAAAGAACCCGCCGATCTACGTCTACGACACGTCGGGCCCGTACACGGACCCGGACGCGAAGATCGACATTCGC
GCGGGCCTGCCCGCGCTGCGCCAGCGCTGGATCGACGCGCGCGGCGACACCGAGACGCTCGCGGGCCTCACGAGCGACTA
CGGCCGCGAGCGCGCGGCCGATCCGGCGACAGCCGAGCTGCGCTTTCCCGGCCTGCACCGCCATCCGCGCCGCGCGAAGG
CGGGCAAGAACGTCACGCAGATGCACTACGCGCGCCAGGGCATCATCACGCCGGAAATGGAATACATCGCGATCCGCGAG
AACCAGCGCCGCGCCGAGTATCTGGAAAGCCTGAAGGCAAGCGGCCCGAACGGCGCGAAGCTCGCCGCGATGATGGGCCG
CCAGCACGCGGGCCAGGCATTCGGCGCCGCCGCGTTCGGCGCGAACGCGCCGGCCGAGATCACGCCGGAGTTCGTGCGCG
ACGAAGTCGCGCGCGGCCGCGCGATCATCCCGGCGAACATCAACCACCCGGAAACCGAGCCGATGATCATCGGCCGCAAC
TTCCTCGTGAAGATCAACGCGAACATCGGCAATTCGGCCGTCACGTCGTCGATCGGCGAGGAAGTCGACAAGATGACGTG
GGCGATCCGCTGGGGCGGCGATACGGTGATGGATCTGTCGACCGGCAAGCACATCCATGAAACGCGCGAGTGGATCATCC
GCAACAGCCCGGTGCCGATCGGCACGGTGCCGATCTACCAGGCGCTGGAGAAAGTCAACGGCAAAGCCGAGGACCTGACC
TGGGAAATCTTCCGCGACACGCTGATCGAGCAGGCCGAGCAAGGCGTCGACTACTTCACGATCCACGCGGGCGTGCGCCT
GCAATACGTGCCGCTCACCGCGAACCGGATGACGGGCATCGTGTCGCGCGGCGGCTCGATCATGGCGAAGTGGTGCCTCG
CGCACCACAAGGAAAGCTTCCTGTACGAACACTTCGAAGAGATCTGCGAGATCATGAAGGCGTACGACGTGAGCTTCTCG
CTCGGCGACGGCCTGCGCCCCGGCTCGATCTACGACGCGAACGACGAAGCGCAGCTCGGCGAACTGAAGACGCTCGGCGA
GCTCACGCAGATCGCGTGGAAGCACGACGTGCAGGTGATGATCGAAGGCCCCGGCCACGTGCCGATGCAGTTGATCAAGG
AGAACATGGATCTTCAGCTCGACTGGTGCAAGGAAGCGCCGTTCTACACGCTCGGGCCGCTGACCACCGACATCGCGCCG
GGCTACGACCACATCACGTCGGGCATCGGCGCCGCGATGATCGGCTGGTTCGGCACCGCGATGCTGTGCTACGTGACGCC
GAAGGAGCACCTCGGGCTGCCGAACAAGGACGACGTGAAGGAAGGCATCATCACGTACAAGCTCGCCGCGCACGCGGCCG
ACCTGGCGAAGGGCCACCCGGGCGCGCAGGTACGCGACAACGCGCTGTCGAAGGCGCGCTTCGAGTTCCGCTGGCAAGAC
CAGTTCAACCTGGGGCTCGACCCGGACAAGGCGCGAGAATTCCACGACGAAACGCTGCCGAAGGATTCGGCGAAGGTCGC
GCATTTCTGCTCGATGTGCGGCCCGCACTTCTGCTCGATGAAGATCACGCAGGACGTGCGCGAGTTCGCCGCTCAGCAGG
GCGTGTCGGAAAACGACGCGCTGAAGAAGGGGATGGAAGTGAAGGCGGTCGAGTTCGTGAAGAGCGGCTCGGAGATCTAT
CACCGCCAGTGA

Protein sequence :
MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIR
AGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRE
NQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRN
FLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLT
WEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFS
LGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAP
GYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQD
QFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIY
HRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 75
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 75
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74