Gene Information

Name : fliI (GBP346_A0133)
Accession : YP_002894860.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 116005 - 117576 bp
Length : 1572 bp
Strand : -
Note : identified by match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR03496

DNA sequence :
ATGGTGAGCGACGTCTGCGGCGGCGCGCTCGGCCGCGACGAACTCGACGCGCTCGAACGCGAGCTCGCGCTCGCATCGCG
CGGCCCCGAGCACGAAGACGCGGCCGCGCACGGCGACGGCTTCGGCGCCCATCATCACGCGCCCCCGCGCCCGCTCGCGA
TGGGCGCGCCGAGCTCGCGCGCGACGCTCGCGAACCCGCATCTCGCGCATTGGCGCGCACATCTGGACGGCATCCGCGAG
CGCAACGCGCGCGCGCTGCCGCTGCGCCCGTGCGGACGCCTCACCCGCGCGGCGGGCCTCGTGCTCGAAGCGATCGGGCT
GCGCCTGTCGGTCGGCGCCGAATGCACGATCGAGCTGCCCGCGGGCAGCGCGCTGCCGTATGCGCAGGCCGAGGTCGTCG
GCTTCGCGGGCGAGCGCCTCTTCCTGATGCCGACCACCGCGGTCGCGGGCGTGCTGCCCGGCGCGCGCGTGTGGCCGCTC
GAGAGCGCGCCCGTCGCCGATCCGCTCGCGGGCGCGAAGCGGCTGCCCGTCGGCTGGGAAATGCTCGGGCGCGTCGTGGA
CGCGTCGGGCCGCCCGCTCGACAATCTCGGGCCGCTCGCGTCGAAGGTCGACGCGCCGCTCACCGCGCCGTCGATCAACC
CGCTCGATCGCGAGCCGATCCATCACGTGCTCGACGTCGGCGTGCGCGCGATCAACGGGCTGCTGACCGTCGGCCGCGGC
CAGCGGATGGGCCTCTTCGCGGGCTCGGGCGTCGGCAAATCGGTGCTGCTCGGCACGATGGCGCGCTACACGAGCGCCGA
GGTGATCGTGATCGGCCTGATCGGCGAGCGCGGCCGTGAAGTGAAGGAGTTCATCGAGCAGATCCTCGGCGAGGACGGGC
TCGCACGCTCGGTCGTCGTCGCGGCGCCCGCCGACGTGTCGCCGCTGCTGCGCATGCAGGGCGCGGCCTACGCGACGACG
CTCGCCGAATACTTCCGCGATCAGGGCAAGCACGTGCTGCTGCTGATGGATTCGCTCACGCGCTATGCGATGGCGCAGCG
CGAGATCGCGCTCGCGATCGGCGAGCCGCCCGCGACGAAGGGCTATCCGCCGTCGGTGTTCGCGAAGCTGCCGGCGCTCG
TCGAGCGCACCGGCAACGGCCCCGAGGGCGGCGGCTCGATCACCGCGTTCTACACGGTGCTCACCGAAGGCGACGACCAG
CAGGACCCGATCGCCGATTCCGCGCGCGCGATTCTCGACGGCCACGTCGTGCTGTCACGCTCGCTCGCGGAAGCCGGCCA
CTATCCGGCCATCGACATCGAAGCGTCGATCAGCCGCGCGATGACCGCGCTGATCGACGATGCGCACCTCGATCGCGTGC
GCCAGTTCAAGCAGATGCTGTCGCGCTACCAGCGCAACCGCGACCTGATCGCGGTCGGCGCGTACGCGCCGGGGCGCGAT
GCGCAGCTCGACCGCGCGATCGCGCTGTACCCGCGCATCGAATCGTTCCTGCAGCAGGGCTTTCGCGAATGCGCGCCGTA
TGCGCCGAGCCTCGCCGCGCTCGATGCGCTGTTCGAATCCGAAGGAGGCTGA

Protein sequence :
MVSDVCGGALGRDELDALERELALASRGPEHEDAAAHGDGFGAHHHAPPRPLAMGAPSSRATLANPHLAHWRAHLDGIRE
RNARALPLRPCGRLTRAAGLVLEAIGLRLSVGAECTIELPAGSALPYAQAEVVGFAGERLFLMPTTAVAGVLPGARVWPL
ESAPVADPLAGAKRLPVGWEMLGRVVDASGRPLDNLGPLASKVDAPLTAPSINPLDREPIHHVLDVGVRAINGLLTVGRG
QRMGLFAGSGVGKSVLLGTMARYTSAEVIVIGLIGERGREVKEFIEQILGEDGLARSVVVAAPADVSPLLRMQGAAYATT
LAEYFRDQGKHVLLLMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERTGNGPEGGGSITAFYTVLTEGDDQ
QDPIADSARAILDGHVVLSRSLAEAGHYPAIDIEASISRAMTALIDDAHLDRVRQFKQMLSRYQRNRDLIAVGAYAPGRD
AQLDRAIALYPRIESFLQQGFRECAPYAPSLAALDALFESEGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-75 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-64 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 7e-65 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-65 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-65 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-64 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-75 46
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-76 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-76 46
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-76 46
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-76 46
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-74 46
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-74 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-75 46
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-75 46
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-70 46
escN AAL57542.1 EscN Virulence LEE Protein 5e-70 46
escN AAC38383.1 EscN Virulence LEE Protein 3e-70 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-70 46
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-70 46
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-70 46
escN AAK26715.1 EscN Virulence LEE Protein 5e-70 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-70 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-70 46
escN AAC31513.1 L0034 Virulence LEE Protein 2e-70 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-70 46
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-70 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-70 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-70 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-62 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-66 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-66 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-65 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-65 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-64 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-67 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 5e-58 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 5e-58 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-66 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-66 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-66 42
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-63 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-57 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG2499 Protein 0.0 100
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG2331 Protein 3e-137 70
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG1254 Protein 2e-119 62
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG0515 Protein 8e-65 47
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG0192 Protein 8e-77 46
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG0730 Protein 2e-70 46
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG0812 Protein 1e-70 46
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG2144 Protein 7e-77 45
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG0390 Protein 7e-74 45
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG0048 Protein 4e-74 44
fliI YP_002894860.1 flagellar protein export ATPase FliI VFG2459 Protein 3e-60 41