Gene Information

Name : GBP346_A1152 (GBP346_A1152)
Accession : YP_002895874.1
Strain : Burkholderia pseudomallei MSHR346
Genome accession: NC_012695
Putative virulence/resistance : Unknown
Product : site-specific recombinase, phage integrase family
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 1108933 - 1110207 bp
Length : 1275 bp
Strand : -
Note : identified by match to protein family HMM PF00589

DNA sequence : 
TTGCTCAGTGACAGCCGGAGAAAGTGTTGGTATTTTTGTTGGTATCAGCAGATACCAACAATGCCTCTCACTGACGTGCA
GGTACGGAACGCGAAGGCCAGCGCGGCCCCGTACAAACTCACGGACGGCAACGGGATGTTCTTACTCGTCCAACCGAACG
GCGCGAAGTACTGGCGCTTGTCCTACCGCTTCCTTGGCAAGCAGAAGACGCTCGCCCTCGGCGTCTATCCGGCCGTCACG
CTCGCGACGGCGCGGAAGAAGCGCGACGAAGCCCGCGAGCAGCTCGCGGCCGGCATAGATCCGGGCGAGGCGAAGAAGGA
AGCCAGACGGACCGCCGAGATCGCGGCGGCCAACTCGTTCGAGGCGGTAGCACGCGAGTGGTTCGACTCGCAGCGTCCGG
GCTGGAGCGACGGCTACGCGGAGAAGGTGCTGAATTCGCTTGAGGTCGACGTGTTCCCGAAGATCGGCCCTCGCCCGATC
GCGGAGATCGACTCGCCGCAGATGCTCAGCATCGTTCGCGAGGTCGAGGCGCGAGGCGTGCGTGAGACGGCGAAGCGGAT
CCTCCAGCGCTCTCGCGCGGTCTTCCAGTACGGAATCGTGACCGGGCGATGTTCCAGGAATCCGGCGGCCGACATCGACG
CGCAGACGGCCTTGAAGAAGGGGCCGGGCGTGCAGCACATGGCCCGCGTCAAGGCGACAGAGATTCCGCAGCTCATGCGC
GACATCGACGCTTACCAAGGTGACCTAGTCACGCGGCTCGCGCTCCGCCTGATGGCACTGACCTGCGTGCGGACAACGGA
AATGATCCGTGCAGAGTGGTCGGAGTTTGACGAGGCCGCCGCAGAATGGCGCGTTCCGCCTGAACGCATGAAGATGCGCG
ACCCGCACATCGTGCCGCTGTCGCGGCAGGCACTCGACGTACTCGCCCAGCTCCGCGCGCTCAACGGCCAGCATCGATTC
GTGTTCTACAGCGTGCAAGGCCGCAGCCACATTTCGAACAACACCATGCTCTACGCGCTCTATCGCATAGGCTACAAGTC
GAGAATGACGGGACACGGGTTTCGCGGGCTGGCGGCTACGGCTCTGCGTGAACTCGGCTTCGGCCGGGACGTCGTCGAGC
GCCAGATGGCGCACGCCGAACGAAATCAGGTGACGGCCGCCTACGTCCACGCTGAGTATTTGCCGGAGCGCAGACGAATG
ATGCAGGCGTGGGGCGATCATCTCGACCGCCTTAAGGCAGGAGCAGAGATTGTCTCAATCGCGTCTGCCCGATAG

Protein sequence : 
MLSDSRRKCWYFCWYQQIPTMPLTDVQVRNAKASAAPYKLTDGNGMFLLVQPNGAKYWRLSYRFLGKQKTLALGVYPAVT
LATARKKRDEAREQLAAGIDPGEAKKEARRTAEIAAANSFEAVAREWFDSQRPGWSDGYAEKVLNSLEVDVFPKIGPRPI
AEIDSPQMLSIVREVEARGVRETAKRILQRSRAVFQYGIVTGRCSRNPAADIDAQTALKKGPGVQHMARVKATEIPQLMR
DIDAYQGDLVTRLALRLMALTCVRTTEMIRAEWSEFDEAAAEWRVPPERMKMRDPHIVPLSRQALDVLAQLRALNGQHRF
VFYSVQGRSHISNNTMLYALYRIGYKSRMTGHGFRGLAATALRELGFGRDVVERQMAHAERNQVTAAYVHAEYLPERRRM
MQAWGDHLDRLKAGAEIVSIASAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 1e-81 46
ECs4534 NP_312561.1 integrase Not tested LEE Protein 1e-81 46
int AAC31482.1 CP4-like integrase Not tested LEE Protein 7e-82 46
int ACU09430.1 integrase Not tested LEE Protein 7e-82 46
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 9e-75 46
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 9e-76 46
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 7e-76 46
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 4e-76 46
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-76 46
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-76 46
int AAK16198.1 Int Not tested PAI-I AL862 Protein 8e-77 46
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 8e-77 46
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 7e-76 46
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 5e-76 46
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 7e-76 46
int AAL51028.1 CP4-like integrase Not tested LEE Protein 5e-76 46
int-phe AAL60261.1 Int-phe Not tested LEE Protein 5e-76 46
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-76 46
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-76 46
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 1e-76 46
int AAK00456.1 Int Not tested SHI-1 Protein 1e-68 46
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 1e-76 46
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 3e-75 46
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-79 45
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-81 45
aec33 AAW51716.1 Int Not tested AGI-3 Protein 7e-82 45
int AAD44730.1 Int Not tested SHI-2 Protein 5e-81 45
int CAC39282.1 integrase Not tested LPA Protein 1e-81 45
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-79 45
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-79 45
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-79 45
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 4e-75 45
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 2e-66 45
int CAC81896.1 integrase Not tested LEE II Protein 5e-68 45
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 2e-70 43
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 2e-70 43
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 2e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GBP346_A1152 YP_002895874.1 site-specific recombinase, phage integrase family VFG0783 Protein 4e-82 46
GBP346_A1152 YP_002895874.1 site-specific recombinase, phage integrase family VFG0626 Protein 8e-77 46
GBP346_A1152 YP_002895874.1 site-specific recombinase, phage integrase family VFG1693 Protein 1e-76 46
GBP346_A1152 YP_002895874.1 site-specific recombinase, phage integrase family VFG0598 Protein 6e-80 45
GBP346_A1152 YP_002895874.1 site-specific recombinase, phage integrase family VFG1536 Protein 1e-66 45