Gene Information

Name : leuS (Tola_2823)
Accession : YP_002894002.1
Strain : Tolumonas auensis DSM 9187
Genome accession: NC_012691
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 3101896 - 3104481 bp
Length : 2586 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCAGTTATGCAAGAACAATATAATCCCCAGTCCCTGGAGCCGGAAGTTCAACGGCATTGGGATAAACAGCAGACATT
CAAAGCCTTCGAGAAAGTAGATAAAGAAAAATTCTACTGCCTGTCTATGTTTCCTTATCCTTCAGGCCGTCTGCACATGG
GTCATGTGCGTAACTACACCATCGGTGACGTGATCTCCCGTTACCAGCGCCTGAATGGCAAAAACGTACTGCAACCGATC
GGTTGGGATGCGTTCGGTCTGCCGGCAGAAAACGCGGCGATCAAAAACAACTCTGCACCAGCCAAATGGACCTACGAGAA
CATCGAGTACATGAAAGGTCAGCTGAAGATGCTGGGTCTTTCTTACGACTGGGATCGTGAACTGGCGACCTGTACCCCGC
AATATTACCGCTGGGAACAATGGTTCTTCACCGAACTATATAAAAAAGGTCTGGTATATAAGAAGACCTCTTCCGTGAAC
TGGTGTCCGAATGACCAGACCGTACTGGCCAACGAACAGGTGCAGGATGGTTGCTGCTGGCGTTGTGATACGCCGGTAGA
ACAGAAAGAAATTCCGCAGTGGTTTGTAAAAATCACCGCGTACGCTGAAGAGCTGCTGACCGATCTGGACAAGCTGGATG
GCTGGCCGGAAATGGTGAAAACCATGCAGCGCAACTGGATTGGCCGCTCTGAAGGTCTGACCATGACTTTCCATGTAGAA
AACAGCGAACAATCGTTTGATATCTACACCACCCGTCCGGACACCCTGATGGGCGTGACGTATGTCGCCGTGGCTGCGGC
ACATCCGCTGGCAAAACAGGCTGCAGAAAACAACGCCGCGCTGGCTGACTTCCTTGAAGAGTGCAAAAACACCAAAGTTG
CCGAAGCTGAACTGGCGACGATGGAGAAAAAAGGCATGGCCACCGGCCTGTATGCCCTGCACCCGCTGGATGGCCGTCGC
GTACCAATCATGGTCGCTAACTTCGTACTGATGGACTACGGTACTGGTGCAGTCATGGCCGTACCTGCGCACGACCAGCG
TGACTTTGAATTTGCCCATAAATACGGTCTGGAAATTCGTGCCGTGATCGCGGCTGAAGATGGTTCTGCTCCGGATATCT
CTGCCGCTGCTTACACCGAGAAAGGTGTGCTGTTTAATTCCGGTGAATTTGATGGTCTGGACTTCAAACAAGCCTTTGAT
GCCATCTGTACCAAACTGGAATCGCAGGGTTTAGGTAAACGCACCGTTAACTTCCGTCTGCGTGACTGGGGTGTCTCCCG
TCAGCGTTACTGGGGTGCACCAATCCCGATGCTGACGCTGGAAGACGGCACCGTGGTACCAGCACCAGCTGACCAGCTGC
CGGTGATTCTGCCGGAAGACGTAGTGATGGACGGCGTGCAGAGCCCGATCAAGGCCGATCCGGAGTGGGCAAAAACGACC
TACAACGGTCAGCCTGCGCTGCGCGAAACCGATACCTTCGATACCTTCATGGAATCGTCCTGGTATTTCGCCCGTTACTG
CTGCCCGGATTACGAACAAGGCATGCTGGATACCGATCGTGCTAACCACTGGTTGCCGGTAGATCAATATATCGGTGGTA
TCGAACACGCCTGTATGCACCTGCTGTATGCGCGTTTCTTCCACAAACTGCTGCGTGACTCCGGCATGGTGAAGAGCGAT
GAACCGTTCACTCGCCTGCTGTGTCAGGGCATGGTGCTGGCTGATGCCTTCTACTACACCGAACACGGTGCCCGCGTCTG
GGTCAGCCCGACCGATGTCAAAGTAGAGCGTGACGAAAAAGGCCGTATCATCAAAGCAGTGGATAATGAAGGCCGTGAAG
TGATCCACGCCGGCATGACCAAGATGTCGAAATCGAAGAACAACGGTATCGACCCGCAACTGATGGTGGAACGTTACGGT
GCCGACACCGTACGTCTGTTCATGATGTTTGCCTCACCAGCCGATATGACGCTGGAATGGCAGGAATCAGGTGTCGATGG
TGCACAACGTTTCCTGAAACGTCTGTGGAAAGCGGTGGCCGAACATACTGCGAAAGGTGCCGCACCAGAACTGGACGTGG
CGAGCCTGAGCAATGAGCAGAAAACACTGCGCCGTGAACTGCATAAGACCATTGCCAAGTTCAGCGATGACATTGGTCGT
CGTCAGACCTTCAACACCGCCATTGCTGCTGTAATGGAGCTGATGAACCGTGTCGCGAAAGCACCACAAGAGTCAGACCA
GGATCGCGCACTGGTACAGGAAGTGCTGACCAACGTCGTACTGATGCTCTATCCAATCACCCCGCATGTCTGCTTCCATC
TGTGGCAGGCGCTGGGTAATGCGGATATCGATCAGGCCGCCTGGCCGGTAGCCGATGCCGCCGCGATGGTGGAAGACGAA
AAACTGGTGGTGGTACAGGTCAATGGTAAAGTGCGCGGTAAGCTGACCGTGGCTGCCGATGCCACCCAGGAACAGGTACA
GGCACTGGCGATGCAGGATCACACTGTGGCGAAGTTCACTGCTGATCTGACCGTGCGTAAAGTGATCTATGTCCCGGGCA
AACTGCTCAATATCGTGGTTGGCTAA

Protein sequence :
MSVMQEQYNPQSLEPEVQRHWDKQQTFKAFEKVDKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRLNGKNVLQPI
GWDAFGLPAENAAIKNNSAPAKWTYENIEYMKGQLKMLGLSYDWDRELATCTPQYYRWEQWFFTELYKKGLVYKKTSSVN
WCPNDQTVLANEQVQDGCCWRCDTPVEQKEIPQWFVKITAYAEELLTDLDKLDGWPEMVKTMQRNWIGRSEGLTMTFHVE
NSEQSFDIYTTRPDTLMGVTYVAVAAAHPLAKQAAENNAALADFLEECKNTKVAEAELATMEKKGMATGLYALHPLDGRR
VPIMVANFVLMDYGTGAVMAVPAHDQRDFEFAHKYGLEIRAVIAAEDGSAPDISAAAYTEKGVLFNSGEFDGLDFKQAFD
AICTKLESQGLGKRTVNFRLRDWGVSRQRYWGAPIPMLTLEDGTVVPAPADQLPVILPEDVVMDGVQSPIKADPEWAKTT
YNGQPALRETDTFDTFMESSWYFARYCCPDYEQGMLDTDRANHWLPVDQYIGGIEHACMHLLYARFFHKLLRDSGMVKSD
EPFTRLLCQGMVLADAFYYTEHGARVWVSPTDVKVERDEKGRIIKAVDNEGREVIHAGMTKMSKSKNNGIDPQLMVERYG
ADTVRLFMMFASPADMTLEWQESGVDGAQRFLKRLWKAVAEHTAKGAAPELDVASLSNEQKTLRRELHKTIAKFSDDIGR
RQTFNTAIAAVMELMNRVAKAPQESDQDRALVQEVLTNVVLMLYPITPHVCFHLWQALGNADIDQAAWPVADAAAMVEDE
KLVVVQVNGKVRGKLTVAADATQEQVQALAMQDHTVAKFTADLTVRKVIYVPGKLLNIVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-149 41