Gene Information

Name : Tola_2404 (Tola_2404)
Accession : YP_002893587.1
Strain : Tolumonas auensis DSM 9187
Genome accession: NC_012691
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 2630003 - 2632012 bp
Length : 2010 bp
Strand : +
Note : KEGG: xca:xccb100_2412 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I DNA-binding; DNA to

DNA sequence :
ATGCGGCTATTTCTCTGCGAAAAACCTTCGCAAGGCAAGGACATCGGGCGCCTGTTGGGCGCAAGGCAGCGCGGCAATGG
TTGCCTCAACGGCCCCGGCGTCGTCGTGACGTGGTGCATTGGCCACCTTGTCGAAGCCGCGCCGCCGGAAGCCTATGACG
AACAGCTCAAGCGCTGGACGATCGAGCAACTTCCCATTATTCCCCAGCACTGGCGGGTTGAGGTCAAACCCAAGACCGCA
GCGCAATTCAAGGTCGTCAAAGACCTTCTGAGCAAGGCGACCGAACTGGTCATCGCCACCGACGCCGATCGCGAAGGCGA
ACTGATTGCGCGCGAGATCATCGATCTCTGTGGCTATCGCGGCCCCATTCAACGGCTGTGGTTGTCAGCACTGAACGACG
CCTCGATCCATGCCGCGCTCGGCAAGCTGAAGCCTTCGGGCGACACGCTGCCCATGTATCACTCGGCGCTGGCGCGCTCC
AGAGCGGACTGGCTGGTGGGGATGAACCTGAGCCGCCTGTTCACCCTCCTGGGGCGCCGGGCCGGCTATGACGGCGTGCT
GTCGGTCGGACGCGTGCAGACCCCCACGCTCAGACTGGTGGTCGATCGCGATCGTGAAATCGCGGCCTTCGTCTCCGTCC
CGTTCTGGTCCATCGAAGTGGCGCTGTCCTGCACAGGCCAGACATTCACCGCGCAGTGGCTGCCGCCATCGGCCAGTACC
GACGATGCAGGCCGTTGCCTGCAGGAGCCTGTTGCGCAGCAGGCGGTGCAGCGCATCCGCGCCGCTGGCGCTGCTCAGAT
GGTATCGGTCGAGACCGAACGCATGCGCGAAGGCGCGCCATTGCCGTTTGATCTCGGCACCTTGCAGGAAGTGTGTTCCA
AGCAGTTCGGCCTCGATGTCCAGGAGACGCTAGAGATCGCCCAATCCCTGTACGAGACGCACAAGGCCACCACCTATCCA
CGTAGCGACTCCGGCTATCTTCCCGAAAGCATGCATGCCGAAGCGCCCACGGTGCTCGACAGTCTGCTCAAGACCGATCC
GAGCCTGCGCCCGATCATCGACCAGCTCGACCGCACCCAGCACTCGCGCGCCTGGAACGACGCCAAGGTATCGGCCCACC
ACGGCATCATCCCCACGCTCGAACCCGCCAACCTGTCGGCGATGAGCGAGAAGGAACTGGCCGCCTACCGCCTGATCCGC
GCCCACTACCTGGCGCAATTTCTTCCGCCGCACGAGTTCGACCGCACGACAGCAAGGTTCTCTTGCGGCGACCAGACATT
GCAGGCCGTGGGCAAGCACGTAGTCGTGCCGGGTTGGCGCCTGGTACTGGCCGAGCCGCAACCCGACGATGCCGGCGATG
ACGCCGCACCCCGCAGCCAGGTGCTGCCAGCGCTACACCAAGGGCTGGCGTGCCAGGTGGCTGGGGTCGATCTGAAGGCG
CTCAAGACGCTGCCGCCGCGCCCGTACACCCAAGGTGAGTTGGTCAAGGCGATGAAAAGCGTCGCCAAACTGGTGTCAGA
CCCACGCCTGAAACAGAAGCTGAAAGATTCCGTGGGCATCGGCACCGAAGCGACCCGCGCCAATATCATCGGCGGCCTGC
TGAACCGTGGCTACCTGATCAAGAAAGGACGGGCCATCCGCGCCTCGGATGCCGCCTTCACGCTCATCGACACCGTGCCC
GCCGCGATCGCCGATCCCGGCACAACCGCGGTGTGGGAACAGGCGCTCGACATGATCGAAACCGGACAGCTCGCGCTCGA
TACCTTCATCGACAAGCAGGCGGCCTGGGTCACGCAGTTGATTGCGCAGTACCGTGGCACCTCGCTGTCCATCAAGATTC
CCGAGGGGCCAGCATGCCCGCAGTGTGGCGGTGCCACGCGCCAGCGCAGCGGCAAGAGCGGTCCATTCTGGTCCTGCGCG
AAATACCCCGACTGCAAGGGAACGCTGCCCATCGAATCGGGCAAGCGTGCCGCGCCGCGCAAGCGCCGCGGTGGCCCGAA
GGCCTCCTGA

Protein sequence :
MRLFLCEKPSQGKDIGRLLGARQRGNGCLNGPGVVVTWCIGHLVEAAPPEAYDEQLKRWTIEQLPIIPQHWRVEVKPKTA
AQFKVVKDLLSKATELVIATDADREGELIAREIIDLCGYRGPIQRLWLSALNDASIHAALGKLKPSGDTLPMYHSALARS
RADWLVGMNLSRLFTLLGRRAGYDGVLSVGRVQTPTLRLVVDRDREIAAFVSVPFWSIEVALSCTGQTFTAQWLPPSAST
DDAGRCLQEPVAQQAVQRIRAAGAAQMVSVETERMREGAPLPFDLGTLQEVCSKQFGLDVQETLEIAQSLYETHKATTYP
RSDSGYLPESMHAEAPTVLDSLLKTDPSLRPIIDQLDRTQHSRAWNDAKVSAHHGIIPTLEPANLSAMSEKELAAYRLIR
AHYLAQFLPPHEFDRTTARFSCGDQTLQAVGKHVVVPGWRLVLAEPQPDDAGDDAAPRSQVLPALHQGLACQVAGVDLKA
LKTLPPRPYTQGELVKAMKSVAKLVSDPRLKQKLKDSVGIGTEATRANIIGGLLNRGYLIKKGRAIRASDAAFTLIDTVP
AAIADPGTTAVWEQALDMIETGQLALDTFIDKQAAWVTQLIAQYRGTSLSIKIPEGPACPQCGGATRQRSGKSGPFWSCA
KYPDCKGTLPIESGKRAAPRKRRGGPKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 84
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 76
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 65
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 5e-167 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 7e-167 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 7e-167 51
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 8e-161 50
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-155 49