Gene Information

Name : Tola_2373 (Tola_2373)
Accession : YP_002893556.1
Strain : Tolumonas auensis DSM 9187
Genome accession: NC_012691
Putative virulence/resistance : Resistance
Product : Dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 2600373 - 2600864 bp
Length : 492 bp
Strand : -
Note : PFAM: dihydrofolate reductase region; KEGG: aha:AHA_3377 dihydrofolate reductase

DNA sequence :
ATGCAGATTTCTTTGATTGTAGCGATGGCTCAGCACCGGGTTATCGGACGTGGTAATCAGATGCCCTGGCACTTACCTGC
CGATTTGCGTCATTTTAAAAGAGTCACTTTAGGTAAGCCGGTGATCATGGGTCGTAAAACCTTTGAATCAATTGGCCGCC
CATTACCGGGACGCCGTAATCTGGTGATTACCCGGAACAGTGATTGGCAAGCGGATGGCGTTGAGAGTGTTAACAGCCTG
GATGCGGCTCTGGCGCTGGTAGGCGATGAAGCTGAGGTGATGATCATCGGTGGGGGGCAGTTATACCGTGAAGCGTTGCC
GTTAGCGCACCGGCTGTATCTGACCCATATTGATCTGACGGTGAATGATGCAGATACCTGGTTTCCGGATTACTCAGTCT
GTCGCTGGCAGACAGTAGCGGAAGAGATGCACTGTGCTGATGAAAAGAACCCGTATAACTATCGTTTTGAAACCCTTGAA
CGTTGCGCATAA

Protein sequence :
MQISLIVAMAQHRVIGRGNQMPWHLPADLRHFKRVTLGKPVIMGRKTFESIGRPLPGRRNLVITRNSDWQADGVESVNSL
DAALALVGDEAEVMIIGGGQLYREALPLAHRLYLTHIDLTVNDADTWFPDYSVCRWQTVAEEMHCADEKNPYNYRFETLE
RCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
folA-2 YP_189146.1 dihydrofolate reductase Not tested ¥ÕSP¥â Protein 1e-26 43
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 7e-26 42