Gene Information

Name : Tola_1749 (Tola_1749)
Accession : YP_002892945.1
Strain : Tolumonas auensis DSM 9187
Genome accession: NC_012691
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1915478 - 1917682 bp
Length : 2205 bp
Strand : +
Note : TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: bxe:Bx

DNA sequence :
ATGGGACAACCGGAATCCGGAAAAATCAGCAAGATCACTTCGCTGACGCCAGGAAAAAACGGTGCCATTCGCCGGGGAAC
ACCAGCCGCTGTGTCTGAGACAAAACCTGCGCTTAAAATCAGTGGTATCGCCTGCGGATGCGGCTCTTGCGATACGGAAA
CCCCGAAACAGGAATTACCGCCTTCTGAACCCAAGCTCACCACTGCTATCAATTGTGGCTGTGATTCCTGCGATGATGAA
CAAAAGGAGCAAAAGGCAGACACACAGCCCTCTGTGAGTGTTGGCGCCATTAGCTGTAGTTGTGACTCATGTGATGATTC
TCATGAGAGTGTGACTTCAGAAGAAAAACAGTCTCTGCTCACATCCAATCAGAAGCTGGTATTAGCCGGTATTTTTGCTA
TCGCAGCAGAAGCTATCGACTGGTTCAGTGTTTCTGAGTGGCTGGCCGCGTTCTTTGCTCTGATTGCCGTGGCATTAAGT
GGTGTGACGACCTACAAAAAAGGCTGGCAGGCATTACGCCGTTTTGATCCGAACATGCATGCCTTAATGAGTATTGCCGT
GACGGGCGCCTTTCTGATTGGCCAGTGGCCGGAAGCCGCGATGGTCATGGTGCTGTTTAATATTGCAGAGTTTCTGGAAA
GCAAATCGCTGGAACGGGCTCGCAATGCGATTCAGGAACTGATGACACTGACGCCGGAACAGGCATTGGTACAACAATCT
GATAACACATGGAAAGAGCTGTATATAAATACAGTAGGCGTCAATCAGGTCATAAGAATCAAGCCCGGCGTGCGGATCCC
GCTGGATGGTACGGTTATTCGTGGCAGTTCGAGTGTGGATCAGGCCCCTATCACCGGTGAAAGTCTGCCTGCTGAAAAAA
ATGAAGGTGATTTGGTGTATGCCGGTACGATTAATCAGCAAGGATCGTTCGATTACCGGGTCACCGCGACAACGCAAAAT
ACCCTGCTCGCCCGGATTATTCATTCTGTGGAAGAAGCACAGGGAAAACGGGCCCCCATTCAACGTCTGGTCGATCGTTT
TGCCCGTATTTATACGCCGATCATTCTGATTATTGCGGTATTGGTGGCATTGGTTCCGCCATTATTCTTTGCTGCACCCT
GGTTTGAATGGCTTTATAAGGCGCTGGTGTTACTGGTTATTGGTTGCCCGTGTGCACTGGTACTCTCTACACCGGTCGCG
ATAGTTACCGCCCTGTCGGTTGCCGCGCGTCATGGCATTCTGATTAAAGGCGGCCATTACCTCGAACTGGGCAGGAAGCT
GCAAGTGCTGGCGCTGGATAAAACCGGCACTATTACCACCGGGAAACCAGAACTGACGGATATGATCCCGCTGGCAGATA
CCAACATCGCTGAATGTCAGCAAATCGCGGTGGCGCTGGCGTTACATTCCGAACATCCGGTGTCACGGACGATTGTCCGC
GCCTACCCGGAAACCGCCGATCTATCAGTTCAGGATATTACTTCCTTAACTGGTGCAGGTATCCAAGGCGTAATCGCCGG
AGAAACATTCCGTTTGATCAGCCCTAAGGCTTTTGCTGCGAATAACGCCCTGACGGCTCAGGTAGCACAACCGATCAGCC
AGTACGAAGCACAAGGCAAGACAGTTGTATTGTTGGTGAAAGCTGACACCCCGTTAGCACTGTTTGCTGTCGCTGATACG
ATAAAAGCCAGCAGCCAGCAGGCCATTACCGAATTACATCATCTGCATATTCATACCGTCATGCTGACCGGCGATAACGC
ACATACCGCGAACCGGATTGCGACTCAGGCAGGCATTGATCAGGTTTACAGTAATCAGTTACCGGAAGACAAGCTGAATC
AGATAGACACCATGAGTAAGCATCAGATCGTCGGCATGGTGGGTGATGGCATCAATGATGCGCCCGCGTTAGCTCGTGCC
AGTATCGGTTTTGCGATGGGTGGCATGGGCAGTGATACGGCGATCGAGACAGCCGATATTGCGCTGATGGATGATGACTT
GCGCAAAGTGCCGCTGTTTGTACGGCTGTCACAGGCCACCTGGCGCAATATACTGCAAAACATCACTGTGGCACTCGGCA
TCAAAGCCGGCTTCCTGCTGGCAACGCTGCTGGGGTTCGGTACGTTATGGATGGCGGTCTTTGCCGATATGGGAACAAGC
CTGCTGGTGGTCGCGAATGCCATGCGGTTGTTACGGTTTAAGTAG

Protein sequence :
MGQPESGKISKITSLTPGKNGAIRRGTPAAVSETKPALKISGIACGCGSCDTETPKQELPPSEPKLTTAINCGCDSCDDE
QKEQKADTQPSVSVGAISCSCDSCDDSHESVTSEEKQSLLTSNQKLVLAGIFAIAAEAIDWFSVSEWLAAFFALIAVALS
GVTTYKKGWQALRRFDPNMHALMSIAVTGAFLIGQWPEAAMVMVLFNIAEFLESKSLERARNAIQELMTLTPEQALVQQS
DNTWKELYINTVGVNQVIRIKPGVRIPLDGTVIRGSSSVDQAPITGESLPAEKNEGDLVYAGTINQQGSFDYRVTATTQN
TLLARIIHSVEEAQGKRAPIQRLVDRFARIYTPIILIIAVLVALVPPLFFAAPWFEWLYKALVLLVIGCPCALVLSTPVA
IVTALSVAARHGILIKGGHYLELGRKLQVLALDKTGTITTGKPELTDMIPLADTNIAECQQIAVALALHSEHPVSRTIVR
AYPETADLSVQDITSLTGAGIQGVIAGETFRLISPKAFAANNALTAQVAQPISQYEAQGKTVVLLVKADTPLALFAVADT
IKASSQQAITELHHLHIHTVMLTGDNAHTANRIATQAGIDQVYSNQLPEDKLNQIDTMSKHQIVGMVGDGINDAPALARA
SIGFAMGGMGSDTAIETADIALMDDDLRKVPLFVRLSQATWRNILQNITVALGIKAGFLLATLLGFGTLWMAVFADMGTS
LLVVANAMRLLRFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-106 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-108 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-108 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tola_1749 YP_002892945.1 heavy metal translocating P-type ATPase BAC0298 Protein 3e-154 59
Tola_1749 YP_002892945.1 heavy metal translocating P-type ATPase BAC0461 Protein 2e-83 45