Gene Information

Name : Tola_0128 (Tola_0128)
Accession : YP_002891344.1
Strain : Tolumonas auensis DSM 9187
Genome accession: NC_012691
Putative virulence/resistance : Unknown
Product : O-succinylhomoserine (thiol)-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 137887 - 139047 bp
Length : 1161 bp
Strand : +
Note : KEGG: aha:AHA_0589 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein

DNA sequence :
ATGTCGGATTACCAACAGGAAACATATGCTGTCAAATCGGGAATTGCTGTCGATACACAATTCGGTGCTGTAGTCCCGCC
TATTTATTTGTCAACTAATTACACGTTTGCTGGCTTTGGTGAAAAAAGAGAATTTGACTATAGTCGTTCCGGTAATCCAA
CCCGTAGCACCTTGGCTGGTGCGTTGGCTGCACTTGAGGGGGGGGCAGGTGCCGTTTTCACCGGGAGTGGCATGGGCGCT
ATTAACCTAGTAACCGCACTGTTATCTGCGGATGATTTGCTGGTCGCGCCACATGATTGTTATGGCGGGACTTATCGGTT
ATTTCAGCATGTTGCCGCTAAGGGTTCTTACCGCGTGTTGTTTGTTGACCAAACTGATCCGGAAGCATTAGCACAGGCTT
TAGCACAAAAGCCGAAACTGGTATGGATTGAGACGCCATCTAATCCATTGCTCCGCGTGGTTGATATTGCGGCTATTTGC
CAGCAGGCGCATGCAGTCGGGGCTTTGGTGGCGGTTGATAATACCTTCCTGTCGCCGTTACTGCAGCAACCCCTGGCATT
AGGTGCTGATATTGTTGTGCACTCGACAACTAAATATATAAATGGTCACTCCGATGTCGTTGGCGGAGCTGTTATTGCGA
AAGAAACCGAATTACACGAAAAACTGGCTTGGTGGGGTAATTGTCTGGGTCATACCGGTGGTGCTTTTGATGCTTATCTG
ACCTTGCGTGGTCTGCGAACATTAGCACCACGTATGCGTGCGCATCAGGAAAATGCCGCCGCTATTCTGGCATATCTGCA
GCAAAAACCACAGGTGACTAAAATTTATCATCCGGGTTTACCTGATCATCCGGGGCATGAGATTGCAAAGCGGCAACAAA
AAGGTTTTGGTGCCATGCTGAGCTTTGAAGTTGATTTTGATATCGAACAGTTAAAGCAATTTTTGGGTGGTTTGCAGTTG
TTTTGTCTGGCAGAGTCATTAGGTGGAGTAGAAAGTCTGGTAGCTCATCCGGCCAGTATGACTCACGCAGGAATGGATCC
GGAAGCCCGGCGTGTGGCGGGCATTTCGGATCAGTTATTACGTTTATCTGTCGGGATTGAGCATATCACCGATCTGCTGG
CCGATTTGGAACAGGCTTTCGCTTGTGTTGCCAGCAAGTAG

Protein sequence :
MSDYQQETYAVKSGIAVDTQFGAVVPPIYLSTNYTFAGFGEKREFDYSRSGNPTRSTLAGALAALEGGAGAVFTGSGMGA
INLVTALLSADDLLVAPHDCYGGTYRLFQHVAAKGSYRVLFVDQTDPEALAQALAQKPKLVWIETPSNPLLRVVDIAAIC
QQAHAVGALVAVDNTFLSPLLQQPLALGADIVVHSTTKYINGHSDVVGGAVIAKETELHEKLAWWGNCLGHTGGAFDAYL
TLRGLRTLAPRMRAHQENAAAILAYLQQKPQVTKIYHPGLPDHPGHEIAKRQQKGFGAMLSFEVDFDIEQLKQFLGGLQL
FCLAESLGGVESLVAHPASMTHAGMDPEARRVAGISDQLLRLSVGIEHITDLLADLEQAFACVASK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-56 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-55 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-47 42