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Name : Tola_1223 (Tola_1223) Accession : YP_002892426.1 Strain : Tolumonas auensis DSM 9187 Genome accession: NC_012691 Putative virulence/resistance : Unknown Product : HsdR family type I site-specific deoxyribonuclease Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 1332604 - 1335828 bp Length : 3225 bp Strand : + Note : KEGG: sbp:Sbal223_4470 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase DNA sequence : ATGATCACTGAAGACCAACTAGAACAGCAGTGCCTTGATTGGTTTAAAGAGCTGGGTTATCAATATCAAAACGGTTATGA CATTGCGCCTGATGGCGATACGCCTGAACGCGACGATTATCATCAAGTCATCTTGCACCAGCGTTTAGTTGATCAGCTCG GTACGTTAAACCCAAACCTGCCTCATGACACACGGATCGAGCTAGCCAAAACTGTTGCCACCACACAAACACCCATTCTG ATTAAAAATAACCGCGCCTTTCATAAATACCTGATTGAAGGCGTGCCTGTTGAATATTCGGTGATCGAAGATGGACAATC GGTCACGAAAAATACCCACGCTCGCTTGATTGATTTTGAGAAGGTCGAAAACAACGAGTTTTTAGTCGTGAACCAGTTCA CCATTACTGGCACCAAAGGCAATCGTCGCCCTGATGTCGTGGTGTTTATCAACGGCCTGCCCATGGGCGTGATTGAGCTA AAAAATCCTGCTGACGACCATGCAGACATCTGGAATGCCTACAATCAGCTCCAGACCTACAAAGAAGAAATCGCCGATCT GTTTGCATTAAACGAGGCGTTAGTCATCAGTGATGGCTGGACAGCCCGAGTGGGGTCACTCACTGCGAATAAAGAACGTT TTCTACCATGGAAAACCATTGAAAGTGAAGAAGATAAGCCGCTGCTCGAATTTCAACTCGAAACCATGGTACGAGGTTTC TTTAAACCCGAGTTACTGCTTGATTACATTCGCTACTTTGTTCTGTTCGAAAATGATAACGACAAGATCATTAAGAAAAT AGCCGGTTATCACCAGTTTCATGCGGTGCGTGCCGCAGTCAAAGCAACGGTCATTGCCGCCGCATGTAGTGATGGAGTTC GAGATCCAAGAGCGAATTACGCCAATCAAGTGATTTCCGGCAGCAAAAAAGCGGGGGTTGTCTGGCATACTCAAGGGAGT GGAAAGAGCATTTCCATGGTCTGCTATGCCAGCAAATTGTTGCAACAGCCCGAGATGAACAACCCGACTTTGGTGGTGGT CACTGACCGGAATGATTTAGATGGGCAATTGTTTAACACCTTCACCATGGCGCAGGAAACTCTGAAACAAATTCCGCAAC AAGCTGAAGATCGTGACTCGTTACGAGAACTGTTACTGAATCGTCAATCTGGCGGCATCATTTTTACGACAGTTCAGAAG TTCGCACTGCTCGATAATGAACTGGAACATCCGATCCTTTCCGAACGTTCTAATATCGTTGTCGTGTCTGATGAAGCACA TCGTAGCCAATATGGAAATAAAGCTCGTCTCACAGATGTGAAAGATGAAAACGGGAATGTCACTGGTCAACGCTATGTTT ATGGTTATTCCAAATACATGCGTGATGCCCTGCCAAATGCTTCATTCATTGGTTTTACTGGTACGCCAATCTCGATGGAT GACAAAGACACCCGTGGTGTTTTTGGTGATTATGTCTCTATTTATGACATTCAGGATGCGGTAGATGATGGCGCAACCGT GCCAATTTATTATGAGTCTCGCCTTGCCAAGCTCGATATTAACCAAGAAGAAATCGAAGCTTTAAATGACCAGGTAGAAG ACGAGATTGGTGAAGACGAAGAGACATCTGCACGCGAAAAAATCAAATCCCAATGGTCAGCTTTGGAAAAATTGGTTGGC GCTGAACCTCGTATTCAACAAGTCGCCAAAGATTTAGTGGAACATTTTACGACGCGCACCGAGACCTTCCCCGGCAAAGC CATGATTGTGGCAATGAGCCGTGAAATTTGTGTGGATCTCTATAACGCTATCGTCGCAATCAAACCCGATTGGCACAGTG ATGACCCGCATAAAGGGGCAATCAAAGTCGTGATGACCGGCAGTGCATCTGACATTGATAAGATGCAGCCACATATTTAC GATAAGAAAACTAAAAAGCTATTCGAAAAACGCTATAAAGACACCGATGACGAACTTCAGTTGGTGATTGTGCGTGATAT GTGGCTCACCGGTTTCGATGCGCCATGCTGCCATACCATGTATATCGACAAACCGATGAAAGGCCACAACCTGATGCAGG CGATTGCTCGCGTGAACCGGGTGTTTAAAGATAAGCCGGGCGGTTTAGTGGTCGATTATATCGGCATTGCCAATGAATTA AAAAATGCACTAAAAACCTATACCAACAGCCAAGGGAAAGGTAAACCAACGGTTGATACGGCGGAAGCATTTGCGATCCT GATGGAAAAAATCGACATCGTTCGGGGTATGTTTGCTACCCCCGTGGATGGCGCAGTTTTTAATTACCGACCTGATTTTG AAACTAAACCATTGCAACTATTACCGGGCGCGGTAAACCATATCTCTGGTTTGAGCCACAAGAACAACAAAGGTGACGAT GTTCGTGATGGTAAACGCCGTTTCCTCGATGTCATGGCTGCTTTGATGAAAGCTTTTTCATTGTGTAACACGATGGATGA AGTGAATGGCTACAAGAACGAAATAGCCTTCTATGGTGCGATTAAAACTGCATTCTTAAAACATTCAACCGTGGATAAAA AATGCAGTGACGAGCTGCGTAACTCAGCACTCCGTCAAATCCTGAATAATGCGGTTGTTGCAGACGGTGTTGATGATATT TTCAAAATGGTCGGGTTAGACAAGCCGAATATTGGCTTACTCTCTGAAGAGTTTCTCGAAGATGTGAAGAACATGAAAGA GAGAAACCTTGCGGTAGAACTGCTTGAAAAACTGCTGCGTGACGAAGTCAAAGCGCGAATGAAGAATGATGTGGTTCAGG AAAAGAAATACTCTGAACGCATCATGGCAACGTTGCAGAAATACCATAACCGGAATATCGAAACCGCCCAAGTCATTGAA GAACTGATCCAATGGGCCAAAGAGATGCAGGCTGATGCCGAAATGACGGATAAGCTAAATCTCTCAGTCGATGAAATTGC ATTTTATCGAGCATTGGTCACCAATGAAGCTTCTGTGCGTGTTTTGGGTGATGATAGCCTGCGTCAGTTAGCAATCGAAC TGACCCAGCAATTGCGTAAATCAGCCACAGTTGACTGGCAAAAACGAGAAAGCGTTCGTGCGCGTATGCGAAATCTGGTG CGTAGGTTGTTACGTCGCTGGAAATACCCACCTGACGCCGCAGAAGAGGCAATCAAGCTAGTTCTTGAACAAGCTGAAGT ACTGGCTGACGGGTGGTATGCATAG Protein sequence : MITEDQLEQQCLDWFKELGYQYQNGYDIAPDGDTPERDDYHQVILHQRLVDQLGTLNPNLPHDTRIELAKTVATTQTPIL IKNNRAFHKYLIEGVPVEYSVIEDGQSVTKNTHARLIDFEKVENNEFLVVNQFTITGTKGNRRPDVVVFINGLPMGVIEL KNPADDHADIWNAYNQLQTYKEEIADLFALNEALVISDGWTARVGSLTANKERFLPWKTIESEEDKPLLEFQLETMVRGF FKPELLLDYIRYFVLFENDNDKIIKKIAGYHQFHAVRAAVKATVIAAACSDGVRDPRANYANQVISGSKKAGVVWHTQGS GKSISMVCYASKLLQQPEMNNPTLVVVTDRNDLDGQLFNTFTMAQETLKQIPQQAEDRDSLRELLLNRQSGGIIFTTVQK FALLDNELEHPILSERSNIVVVSDEAHRSQYGNKARLTDVKDENGNVTGQRYVYGYSKYMRDALPNASFIGFTGTPISMD DKDTRGVFGDYVSIYDIQDAVDDGATVPIYYESRLAKLDINQEEIEALNDQVEDEIGEDEETSAREKIKSQWSALEKLVG AEPRIQQVAKDLVEHFTTRTETFPGKAMIVAMSREICVDLYNAIVAIKPDWHSDDPHKGAIKVVMTGSASDIDKMQPHIY DKKTKKLFEKRYKDTDDELQLVIVRDMWLTGFDAPCCHTMYIDKPMKGHNLMQAIARVNRVFKDKPGGLVVDYIGIANEL KNALKTYTNSQGKGKPTVDTAEAFAILMEKIDIVRGMFATPVDGAVFNYRPDFETKPLQLLPGAVNHISGLSHKNNKGDD VRDGKRRFLDVMAALMKAFSLCNTMDEVNGYKNEIAFYGAIKTAFLKHSTVDKKCSDELRNSALRQILNNAVVADGVDDI FKMVGLDKPNIGLLSEEFLEDVKNMKERNLAVELLEKLLRDEVKARMKNDVVQEKKYSERIMATLQKYHNRNIETAQVIE ELIQWAKEMQADAEMTDKLNLSVDEIAFYRALVTNEASVRVLGDDSLRQLAIELTQQLRKSATVDWQKRESVRARMRNLV RRLLRRWKYPPDAAEEAIKLVLEQAEVLADGWYA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 63 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 46 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 45 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 45 |
