Gene Information

Name : Tola_1019 (Tola_1019)
Accession : YP_002892232.1
Strain : Tolumonas auensis DSM 9187
Genome accession: NC_012691
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1103318 - 1104757 bp
Length : 1440 bp
Strand : -
Note : KEGG: aha:AHA_1349 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGTTAAGAAGAACCAAAATCGTGACCACATTAGGTCCGGCAACTGACCGCGAAGGCGTGCTGGAAGGGATTCTGGAAGC
CGGTGCCAACATGGTGCGCATGAACTTCTCTCACGGTACGGCTGAAGATCATATTGCCCGTGCCAAAGAGATCCGCGCAC
TGGCTGCCCGTCTGGGTAAATCAGTAGCGATTCTGGGTGACCTGCAAGGCCCGAAAATCCGCGTATCTACGTTCAAAGAC
AACAAAATTATGTTGAAAGTGGGCGACAAATTTCTGCTGGATGCGAACTTGGGTAAAGGTGATGGTACTCAGGAACAAGT
CGGTATCGACTATAAAAAACTACCTGAAGATGTCGTTGCCGGTGACATTTTGTTACTGGACGATGGCCGTGTGCAGCTGA
AAGTAGACAGTGTTGAAGGCAGCAAAATTTTCACTACCGTGACCGTTGGTGGCCCGCTGTCTAACAACAAAGGTATCAAC
AAAAAAGGCGGTGGTCTGTCTGCTCCGGCGCTGACTGAAAAAGATAAAGCCGACATCAAAACTGCAGCGCTGATGCAGGT
TGATTATCTGGCAGTATCTTTCCCGCGTAATGGTGCTGACCTGAACTATGCCCGTGAACTGGCGCGTGAAGCCGGCTGCA
ACGCCAAAATCGTGGCCAAAGTAGAACGTGCTGAAACTGTTGCTACCGACGAAGCGATGGAAGATATCATTCTGGCTTCT
GATGTGGTGATGGTAGCGCGTGGTGATCTGGGCGTTGAAATCGGCGACTCCGAGCTGATGGGCGTTCAGAAAAAACTGAT
CCGTTCCGCACGTAAACTGAACCGTGTTGTTATCACTGCAACTCAGATGATGGAATCGATGATCAAAGCACCGATGCCAA
CCCGTGCTGAAGTTATGGACGTAGCTAACGCGGTTCTGGATGGTACGGATGCGGTCATGCTGTCAGCTGAAACTGCTGCC
GGTGATTTCCCGATTGAAACTGTTACCGCGATGGCTAACGTTTGTCTGGGTGCCGAAAAACACCCAAGCGTGAACGTGTC
TAACCACCGTATGACTCATACTTTTGATACTGTTGAAGAAACAGTTGCTATGAGCACCATGTATGCAGCTAACCACATGC
AAGGTGTAAAAGGCATTATCGCGATGACTGAGTCAGGCACCACGCCGCTGCTGATGTCCCGTTTAAGCTCAGGTCTGCCA
ATTTTCGCACTGTCACGTCATCAACAGACGCTGAACTGGTGTTCTCTGTACCGTGGTGTTACTCCGGTATACTTTGATGC
AGATGAATCACAGCCGGTTATCCAGAACTGCCGTGATGCGATTTCCGAGCTGAAAAGCCGTGGCTATCTGAAATCAGGCG
ATCTGATTCTGATGACTTATGGTGACAAAATTGAAAGTATCGGTGGTACCAACACCTGCAAGATGATGATCGTAGAATAA

Protein sequence : 
MLRRTKIVTTLGPATDREGVLEGILEAGANMVRMNFSHGTAEDHIARAKEIRALAARLGKSVAILGDLQGPKIRVSTFKD
NKIMLKVGDKFLLDANLGKGDGTQEQVGIDYKKLPEDVVAGDILLLDDGRVQLKVDSVEGSKIFTTVTVGGPLSNNKGIN
KKGGGLSAPALTEKDKADIKTAALMQVDYLAVSFPRNGADLNYARELAREAGCNAKIVAKVERAETVATDEAMEDIILAS
DVVMVARGDLGVEIGDSELMGVQKKLIRSARKLNRVVITATQMMESMIKAPMPTRAEVMDVANAVLDGTDAVMLSAETAA
GDFPIETVTAMANVCLGAEKHPSVNVSNHRMTHTFDTVEETVAMSTMYAANHMQGVKGIIAMTESGTTPLLMSRLSSGLP
IFALSRHQQTLNWCSLYRGVTPVYFDADESQPVIQNCRDAISELKSRGYLKSGDLILMTYGDKIESIGGTNTCKMMIVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-79 47
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-52 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-52 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-53 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tola_1019 YP_002892232.1 pyruvate kinase VFG0479 Protein 4e-53 44