Gene Information

Name : pykF (CTB_3291)
Accession : YP_002888832.1
Strain : Chlamydia trachomatis B/TZ1A828/OT
Genome accession: NC_012687
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 376415 - 377872 bp
Length : 1458 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCGCTAGAACGAAAATTATTTGTACGATAGGCCCTGCAACGAATACCCCTGAGATGCTGGAAAAGCTTCTTGATGC
AGGGATGAATGTAGCTCGCCTTAATTTTAGCCACGGGACCCATGAAAGCCATGGCCGGACCATCGCTATTCTTAAAGAAC
TACGAGAGAAGCGCCAAGTTCCTTTAGCTATTATGCTAGATACAAAAGGTCCCGAAATTCGTTTAGGCCAAGTAGAATCT
CCTATAAAAGTACAGCCTGGGGATCGTCTTACTCTCGTTAGCAAAGAAATTTTAGGATCCAAAGAAAGCGGCGTTACTCT
TTATCCAAGTTGTGTATTCCCTTATGTTAGAGAACGAACTCCTGTTCTCATTGATGATGGGTATATCCAAGCAGTGGTGG
TCAATGCTCAAGAGCATATGGTGGAAATAGAGTTTCAAAATTCAGGAGAAATAAAATCCAACAAATCTCTTAGCATCAAA
GATATCGATGTTGCTCTTCCTTTCATGACAGAGAAGGATATTGCAGACTTAAAATTTGGGGTAGAACAAGAACTCGATCT
TATCGCTGCTTCGTTCGTCAGATGTAATGAAGATATTGACAGCATGCGTAAAGTTTTGGAAAGCTTTGGTCGTCCTAATA
TGCCCATCATTGCTAAAATAGAAAATCATTTAGGAGTACAAAATTTCCAAGAGATCGCTAGAGCTGCTGATGGTATCATG
ATTGCACGCGGGGATCTTGGTATTGAATTGTCTATTGTTGAAGTTCCTGGACTACAAAAATTTATAGCCCGAGCATCGAG
GGAAACGGGTCGGTTTTGTATCACTGCAACGCAAATGCTCGAGTCAATGATTCGCAACCCCCTTCCTACACGAGCCGAAG
TCTCTGACGTTGCCAACGCCATTTACGATGGAACCTCTGCAGTCATGTTGTCTGGAGAAACTGCCTTAGGAGCCCATCCT
GTACATGCAGTAAAAACAATGCGTTCCATTATCCAAGAGACTGAGAAGACTTTCGATTACCACGCTTTTTTCCAGCTGAA
CGACAAAAACAGCGCTCTCAAAGTTTCTCCTTATCTTGAAGCCATTGGGTTTTCTGGAATCCAAATTGCAGAAAAAGCAT
CTGCCAAAGCCATTATTGTGTATACCCAGACGGGAGGATCTCCGATGTTTTTATCCAAATATCGACCTTATCTCCCTATT
ATTGCTGTTACCCCTAACCGCAATGTGTACTATCGTTTAGCTGTAGAATGGGGAGTATATCCTATGCTAACCCTAGAATC
GAACCATACAGTCTGGCGTCACCAAGCTTGTGTATATGGAGTAGAAAAAGGAATTCTTTCTAACTATGATAAAATTCTTG
TCTTCAGCCGCGGAGCTGGGATGCAAGATACCAACAATCTCACCTTGACAACTGTGCATGATGTGCTATCCCCCTCTCTT
GACGAGATAGTTCCATAA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPLAIMLDTKGPEIRLGQVES
PIKVQPGDRLTLVSKEILGSKESGVTLYPSCVFPYVRERTPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIK
DIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPIIAKIENHLGVQNFQEIARAADGIM
IARGDLGIELSIVEVPGLQKFIARASRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETALGAHP
VHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALKVSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPI
IAVTPNRNVYYRLAVEWGVYPMLTLESNHTVWRHQACVYGVEKGILSNYDKILVFSRGAGMQDTNNLTLTTVHDVLSPSL
DEIVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-62 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_002888832.1 pyruvate kinase VFG0479 Protein 6e-63 43