Gene Information

Name : Bcav_3915 (Bcav_3915)
Accession : YP_002883918.1
Strain : Beutenbergia cavernae DSM 12333
Genome accession: NC_012669
Putative virulence/resistance : Unknown
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 4334616 - 4336241 bp
Length : 1626 bp
Strand : -
Note : PFAM: N-6 DNA Methylase; TIGRFAM: type I restriction system adenine methylase (hsdM)

DNA sequence :
ATGCCACCGAGGCGTAAGCGAGCCGAGGCGTTGCCGACCGCAGCGACGACGATGAAGGAGCTCAAGGACACGCTCTGGAA
GGCCGCCGACAAGTTGCGCGGCTCGATGGACGCGAGCCAATACAAGGACGTGATCCTGGGCCTGGTGTTCCTGAAGTATG
TGTCGGACGCGTTCGACGAGCGTCGGGCGGTGATCGCAGCGGAGCTCGCGGCGGACGGCATCGGCGAGGAGCAGGCAGGG
CCGTTGCTCGAGGAGGTCGACGAGTACCGCGCCGCCGGTGTCTTCTGGGTGCCGCCTCGGGCGCGCTGGGGGTACCTGGC
GCAGCACGCGAAGGGGCGCCCCGCCGGCGATCCCGAGGGGCAGGCGACGATCGGCGAGCTGGTCGACGAGGCGATGGTCC
TGATCATGGGGACGAACCCCGCGCTCGCGACGACGCTGCCGCAGATCTTCAACAAGGAGAACGTCGACCAGCGTCGCCTC
GGCGAGCTGATCGACCTGTTCAACTCGGCTCGGTTCACGGGCGACGGCGCCCGGAAGGCGCGCGACGTGCTCGGCGAGGT
CTACGAGTACTTCCTGGGAAAATTCGCCGCGGCCGAGGGGAAACGGGGCGGCGAGTTCTACACGCCGCCCGGCGTGGTGC
GGGTGCTCGTCGAGGTGCTCGAGCCGTATCGCGGGCGCGTGTACGACCCGTGCTGCGGGTCCGGCGGGATGTTCGTGCAG
GCGGAGAAGTTCATCGAACGGCATGGCGAGGACCCGCAGGCGATCAGCGTCTACGGCCAGGAGCTGAACGAGCGCACGTG
GCGCATGGCGAAGATGAACCTCGCCGTGCACGGGCTGACGGCGCAGCTCGGGCCGCGGTGGGGCGACACGTTCGCGCGCG
ACGTCCACCCCGACGTCCAGATGGACTTCGTGATGGCGAACCCGCCGTTCAACATCAAGGACTGGGCGCGGAACGCCGAG
GACGCGCGCTGGAAGTTCGGCGTCCCGCCCGCCGGGAACGCCAACTACGCGTGGATCCAGCACATCCTGTCGAAGCTCGC
GCCGGGCGGGTCGGCGGGCGTGGTGATGGCGAACGGATCGATGTCCTCGAACTCCGTGGGTGAGGGGGAGATCCGGGCGG
CGCTCGTGGAGGTTGACCTCGTCTCGTGCATGGTGGCGTTGCCGACGCAGCTATTCAGATCGACAGGCATCCCGGTGTGC
GTGTGGTTCTTCGCGAAGTCCAAGGCTGCGGGTGCCTCTGGGTCGGTCGATCGAACCGGGCAGGTCCTGTTCATCGACGC
GCGGAACCTGGGGCACATGGTGACGCGGGCTGAGCGGGAGCTCTCCGACGAGGACATCGCCCGGATCGCTGGGACGTTCC
ACGCGTGGCGGGGGGCACCGTCCGCTTCGGGGGCGTCCTACGAGGACGTGCCCGGGTTCTGCTACTCGGCGACGCTGTCG
GAGATCAAGGAGGCCGGATACGCGCTCGCGCCCGGGCGGTACGTCGGTGCCCCCGAGGTGGAGGACGACGGTGAGCCGAT
CGAGGAGAAGATCGAGCGGCTGACGGCGGAGCTGTTCGCGCAGTTCGAGGAGTCCGCGCGGCTGGAGCAGGTCGTACGCG
AGCAACTGGGGAGGGTTCGTGGCTAG

Protein sequence :
MPPRRKRAEALPTAATTMKELKDTLWKAADKLRGSMDASQYKDVILGLVFLKYVSDAFDERRAVIAAELAADGIGEEQAG
PLLEEVDEYRAAGVFWVPPRARWGYLAQHAKGRPAGDPEGQATIGELVDEAMVLIMGTNPALATTLPQIFNKENVDQRRL
GELIDLFNSARFTGDGARKARDVLGEVYEYFLGKFAAAEGKRGGEFYTPPGVVRVLVEVLEPYRGRVYDPCCGSGGMFVQ
AEKFIERHGEDPQAISVYGQELNERTWRMAKMNLAVHGLTAQLGPRWGDTFARDVHPDVQMDFVMANPPFNIKDWARNAE
DARWKFGVPPAGNANYAWIQHILSKLAPGGSAGVVMANGSMSSNSVGEGEIRAALVEVDLVSCMVALPTQLFRSTGIPVC
VWFFAKSKAAGASGSVDRTGQVLFIDARNLGHMVTRAERELSDEDIARIAGTFHAWRGAPSASGASYEDVPGFCYSATLS
EIKEAGYALAPGRYVGAPEVEDDGEPIEEKIERLTAELFAQFEESARLEQVVREQLGRVRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 9e-137 52
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-135 51
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 6e-136 51
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 3e-115 46