Gene Information

Name : Bcav_0379 (Bcav_0379)
Accession : YP_002880405.1
Strain : Beutenbergia cavernae DSM 12333
Genome accession: NC_012669
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 424443 - 425714 bp
Length : 1272 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGATCGACCTCAAGGCTCTGCGCGAGAATCCCGACGTCGGCCGGGCCAGCCAGCGCTCTCGCGGCGAGGATCCCGAGCT
CGTGGACCGGCTGCTCGACGCCGACGCCCGGCACCGTGCGTTGCTCACCTCGTTCGAGCAGCAGCGCGCGGAGCAGAAGG
AGCTCTCGCGCGCCGTCGGGAAGGCCGCCCCGCAGGATCGCCCGGCCGTCCTGGCGCACGCGAAGTCGCGCGCGGAGCAG
GTGAAGTCCGCGGAGGCCGACGCCGACCGGGCCAGGGCGGAGCTCGACGCGCTGCTCTCCCGGATGCCGAACATCGTGGC
CGACGGCGTCCCACCGGGCGGCGAGGACGACTACGTGGTGCTGCGGCACGAGGGCACCCCGCGCGACTTCGCCGCGGAGG
GCTTCACGCCGCGGGACCATCTCGAGCTGGGCGAACGGCTCCGCGCGATCGACACGGAGCGCGGCGCGAAGGTCTCGGGG
GCGCGGTTCTTCTACCTCACCGGTCTCGGCGCCCGGCTCGAGCTCGCGCTCCTCAACGCGGCGATCGACAAGGCGCTCAC
GGCAGGTTTCACGCCGGTCATCACGCCGACGCTCGTGAAGCCGGAGATCATGGCCGGCACGGGGTTCCTCGGTGCGCACG
CCGAGGAGGTGTACCGGATCGAGAAGGACGACCTGTATCTCGTGGGGACGAGCGAGGTGGCGCTCGCCGGCTATCACGCG
AACGAGATCGTCGACCTCTCCGACGGCCCGCTGCGCTACGCCGGCTGGAGCGCGTGCTACCGGCGCGAGGCCGGCTCGCA
CGGGAAGGACACGCGCGGCATCATCCGCGTGCACCAGTTCCACAAGGTGGAGATGTTCTCGTACGCGCGCCTCGAGGACG
CCGCCGTCGAGCACGAACGGCTGCTCGCCTGGGAGGAGGAGCTGCTCCGCCTGGTCGAGCTCCCGTACCGCGTGATCGAC
ACGGCGGCCGGCGATCTCGGCTCGAGCGCCGCGCGGAAGTTCGACTGCGAGGCGTGGCTCCCGACGCAGGAGCGCTACCT
CGAGCTGACGTCGACGTCGAACTGCACGTCGTTCCAGGCGCGGCGGCTCGGCACCCGGGAGCGCCTCGAGGACGGCTCGA
CCCGACCCGTCGCCACGCTCAACGGGACGCTCGCCACGACCCGGTGGATCGTCACGATCCTGGAGAACCACCAGAACCCC
GACGGGTCCGTGCGCGTCCCGGCCGGCCTGCAGCCGTATCTCGGCGGGCTGACGGAGCTGCGCGCCTCATGA

Protein sequence :
MIDLKALRENPDVGRASQRSRGEDPELVDRLLDADARHRALLTSFEQQRAEQKELSRAVGKAAPQDRPAVLAHAKSRAEQ
VKSAEADADRARAELDALLSRMPNIVADGVPPGGEDDYVVLRHEGTPRDFAAEGFTPRDHLELGERLRAIDTERGAKVSG
ARFFYLTGLGARLELALLNAAIDKALTAGFTPVITPTLVKPEIMAGTGFLGAHAEEVYRIEKDDLYLVGTSEVALAGYHA
NEIVDLSDGPLRYAGWSACYRREAGSHGKDTRGIIRVHQFHKVEMFSYARLEDAAVEHERLLAWEEELLRLVELPYRVID
TAAGDLGSSAARKFDCEAWLPTQERYLELTSTSNCTSFQARRLGTRERLEDGSTRPVATLNGTLATTRWIVTILENHQNP
DGSVRVPAGLQPYLGGLTELRAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-54 47