Gene Information

Name : Bcav_2215 (Bcav_2215)
Accession : YP_002882228.1
Strain : Beutenbergia cavernae DSM 12333
Genome accession: NC_012669
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2491563 - 2492987 bp
Length : 1425 bp
Strand : -
Note : PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase

DNA sequence : 
ATGCGTAGAGCCAAGATCGTCTGCACCCTCGGCCCAGCGACGGAGTCGCCCGAGATGGTCCAGGCGCTCGTCGACGCGGG
CATGGACGTGGCCCGCATCAACCGGAGTCACGGGGAAGCCGACGAGCACGCCAGGGTCATCGAGCGGGTCCGTGCCGCTG
CCACTGCCGCCGGCCGCGCCGTCGCGATCCTCGTCGACCTCCAGGGTCCGAAGATCCGCCTCGGCCGCTTCGTGGACGGG
AAGCACGAGCTCGCCGAGGGCGACGTGTTCACGATCACCACGGACGACGTGCCCGGTACGAAGGAGCGCGTCTCGACGAC
GTACCCGGGGCTGCCCGGTGACTGCAAGCCGGGCGACGTCATCCTCATCGACGACGGGCGCGTCGCGGTCCGTGTCGTCG
AGGTGACGGCGACCGACGTCGTCACGCGCGTCGAGGTGCCGGGGCCGGTCTCGAACAACAAGGGCCTCAACCTGCCGGGT
GTCGCCGTGAGCGTGCCGGCGATGAGCGAGAAGGACATCGAGGACCTGCGGTGGGGCCTGCGCCTGAAGGCGGACTTCAT
CGCGCTCTCGTTCGTGCGGTCGGCCGCCGACTACGACGACGTGAGCCGGATCATGGACGAGGAGGGCTACCGGGCCCCCG
TCATCGCCAAGATCGAGAAGCCGCAGGCGGTCGAGAACCTCACGGAGATCGTCGACGCGTTCGACGGCATCATGGTGGCG
CGCGGCGACCTCGGCGTGGAGCTGCCGCTCGAGCAGGTCCCGCTCGTCCAGAAGAGCGCGATCGACCTGGCTCGGCGCAA
CGCGAAGCCGGTCATCGTCGCGACGCAGGTGCTGGACTCCATGATCAGCTCGCCGCGCCCGACGCGCGCCGAGACGTCGG
ACTGCGCGAACGCGGTGCTCGACGGCGCCGACGCGGTCATGCTGTCCGGCGAGACGAGCGTGGGGGACTACCCGATCGAG
TGCGTGCGCACGATGGCGCGCATCATCGAGAACACCGAGGACCACGGCCTCGAGCGCATGGCGAAGGCGACCTGGACGCC
GCACACCCGCGGCGGCGTCATCACCCGCGCCGCCAACGAGATCGGCGAGACGCTCGGGGTCAAGTACCTCGTGACGTTCA
CGCAGTCCGGCGACTCGGCCCGCCGCATGTCGCGCCTGCGGTCCTCGCTGCCGCTGCTCGCGTTCACGCCGATGCCCGAG
GTCCGCCGCCAGCTCGCCCTCAGCTGGGGGGTCCAGACCTACCTGGTGCCCGAGGTCGCGCACACGGACGACATGGTCGA
ACAGGTCGACACGACGCTGGCCGCGGGTGGCCTCGCGCAGCAGGGCGACCGGGTCGTGATCGTGTCCGGGGCGCCCCCCG
GCAAGCCCGGCACCACGAACTCGATCCGCGTGCACGCCATCGGCGAGGACTCCGAGCGCCGCTGA

Protein sequence : 
MRRAKIVCTLGPATESPEMVQALVDAGMDVARINRSHGEADEHARVIERVRAAATAAGRAVAILVDLQGPKIRLGRFVDG
KHELAEGDVFTITTDDVPGTKERVSTTYPGLPGDCKPGDVILIDDGRVAVRVVEVTATDVVTRVEVPGPVSNNKGLNLPG
VAVSVPAMSEKDIEDLRWGLRLKADFIALSFVRSAADYDDVSRIMDEEGYRAPVIAKIEKPQAVENLTEIVDAFDGIMVA
RGDLGVELPLEQVPLVQKSAIDLARRNAKPVIVATQVLDSMISSPRPTRAETSDCANAVLDGADAVMLSGETSVGDYPIE
CVRTMARIIENTEDHGLERMAKATWTPHTRGGVITRAANEIGETLGVKYLVTFTQSGDSARRMSRLRSSLPLLAFTPMPE
VRRQLALSWGVQTYLVPEVAHTDDMVEQVDTTLAAGGLAQQGDRVVIVSGAPPGKPGTTNSIRVHAIGEDSERR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-62 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcav_2215 YP_002882228.1 pyruvate kinase VFG0479 Protein 6e-63 44