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Name : leuS (Bcav_1730) Accession : YP_002881748.1 Strain : Beutenbergia cavernae DSM 12333 Genome accession: NC_012669 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 1977166 - 1980072 bp Length : 2907 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGACCGACGCCGCAGCCACGCACCAGCCCGCACCCTCCGCCGCCGACGTCCCGCCGCACCGGTACACGGCCGACCTCGC GGAGCGCATCGAGCTCGCGTGGCAGGACCGGTGGGCGAGCGAGGGCACGTTCCACGCGCCGAACCCGTCCGGTGACCTCG TCGGCGACGCCGCCGCCGAGAAGTTCTACGTGCTCGACATGTTCCCGTACCCGTCGGGCAAGGGGCTGCACGTGGGACAC CCGCTCGGCTACATCGCGACCGACGTCGTCGGGCGGTTCCAGCGGATGCAGGGGCGCAACGTGCTGCACGCCCTCGCCTA CGACGCGTTCGGCCTCCCGGCCGAGCAGTACGCCGTCCAGACCGGCCAGCACCCGCGGATCACCACCGAGCAGAACATCG CGACGATGCGTGGCCAGCTGCGCCGTCTGGGCCTCGGCCACGACGACCGGCGCACGTTCGCTACCACGGATCCCGACTAC GTGCGGTGGACCCAGTGGATCTTCACGCAGCTGTTCGCGTCGTTCTACGACGCCGACGCGCCGCGTCCCGACGGCGGCAC CGGGCGCGCCCGGCCGATCGCCGAGCTCGTGGCGGAGCTCGACGCGGGAACCCGCGCGCTGCCGGACGGTCGCGTGTGGA CCGACCTGGACGCCGCCGCCCGCGCCGACCACCTGGACTCCGTCCGGCTGGCGTACATCTCGAACTCGCCGGTGAACTGG GCGCCGGGCCTCGGCACCGTGCTGTCCAACGAGGAGGTCACAGCCGACGGGCGCAGCGAGCGCGGCAACTTCCCCGTGTT CCAGCGCAACCTGCGCCAGTGGATGCTGCGGATCACCGCGTACGCCGACCGCCTCGTCGACGACCTCGAGCTCATCGAGT GGCCCGAGAAGGTCAAGACGATGCAGCGCAACTGGATCGGTCGCTCCTCGGGCGCGCAGGTGCGCTTCGTCACCGACGCC GGCGACCTGTCCGTGTTCACCACGCGCCCGGACACCCTGTTCGGGGCGACGTTCGTCGCCGTCGCCCCGGAGCACCCGCT GCTCGACGCCCTCGCGAGCGAACAATGGCCCGAGGGCACGTCGGAGGCGTGGACGGGCGCAGCCGCGTCGCCGCGGGAGG CCGTGACCGCCTACCGGCGTGCGGCGTCGACGAAGACCGAGCTGGACCGGCAGACCGAGGGCCGGGACAAGACGGGCGTG TTCACCGGCGCGTTCGCGACGAACCCCGTGACCGGCGCGCGGGTCCCCGTGTTCGTGGCCGACTACGTGCTCATGGGGTA CGGCACCGGCGCGATCATGGCCGTGCCGGGCCAGGACGAGCGTGACTGGGAGTTCGCCACCCGCTTCGGCCTGCCCATCG TGCGCACCGTCGCCCCGCCGGAGGGCTGGGAGGGCGAGGCGTACCCCGGGGAGGGGCCGGCGATCAACTCGGCCAACGAC GAGATCTCGCTCGACGGCCTCGGCGTGGTCGAGGCGAAGGCGGCGATCATCGCGTGGCTCGAGGCCAAGGGGCTCGGCAC CGGCACCGTGACGTACCGCCTGCGGGACTGGCTCTTCAGCCGCCAGCGGTACTGGGGCGAACCGTTCCCCGTCGTGTTCG ACGACGACGGCCGCGCGCACACGCTCCCCGACGAGATGCTGCCCGTCGAGCTGCCCGACGTGCCCGACTACGCGCCGCGC ACGTTCGACCCGCAGGACGCCGACTCCGAGCCCGAGCCGCCCCTGGCGCGCCTGCCCGAGTGGGTGGACGTCGAGCTCGA CCTCGGCGACGGCGTGCGCCGCTACCGGCGCGAGACCAACACGATGCCCAACTGGGCCGGCTCGTGCTGGTACGAGTTGC GTTACCTCGACCCGCACGACGAGAAGGCGCTCGTCGACCCCGACATCGAGCGCTACTGGATGGGGCCGGGCGCCGAGCGG CCAGGCGGTGACCCGACAGACGTCGCCGGCGGAGCGGACCTGTACGTCGGCGGCGTCGAGCACGCGGTCCTGCACCTGCT GTACGCCCGGTTCTGGCACAAGGTCCTGTACGACCTCGGGCACACCGCGAGCCGGGAGCCGTTCCACAAGCTCTTCAACC AGGGGTACATCCAGGCGTACGCGTACGCCGACGCCCGGGGCGTGTACGTCCCGGCGGACGAGGTGCACGAGGAGCCCGGG CTCGACGGCGAGACCACGTACACGTGGCGGGGCGAGCCCGTCGTGCGCGAGTACGGGAAGATGGGTAAGTCGCTGAAGAA CATGGTGACGCCCGACGACATGTACGCCGCGTACGGCGCCGACACGTTCCGCGTGTACGAGATGTCCATGGGGCCGCTCG ACCAGTCGCGCGCGTGGGAGACCCGGGCGGTGGTCGGGGCGCAGCGCTTCCTGCAGCGGCTGTGGCGCAACGTGGTCGAC GAGACCAGCGGCGCCGTCGTCGTCGTGGAGGAGCCGGCCGACGACGCCACCCGGCGCCTCGTGGCCCGCACGATCGCCGA CGTGCGGACCGAGTACGCGGCGATGCGCCCGAACACGGCGATCGCGAAGCTCATCGCCCTCAACAACCACCTGACGACGC TCGCGGCCGTGCCGCGCGAGGCCGTGGAGCCGCTCGTGCTCATGGTCGCGCCCGTCGCCCCGCACATCGCGGAGGAGCTG TGGGCGAGGCTGGGGCACCCGGCGTCGCTGGCGCACGAGCCGTTCCCGACGGCGGATCCCGCCCTGCTGGTCGAGGAGAC GGTGACGTGCGTGGTGCAGGTCGCCGGCAAGGTCCGCGACCGGATCGAGGTGCCGCCCGCCATCGGCGAGGCGGAGCTGC GCGAGCTGGCACTGGCGACCGCGGGCGTCCAGCGTGCCCTGGACGGGCGAGGCGTCCGGACGGTCATCGTGCGCGCACCG AGGCTCGTCAACGTCGTGCCCGCCTGA Protein sequence : MTDAAATHQPAPSAADVPPHRYTADLAERIELAWQDRWASEGTFHAPNPSGDLVGDAAAEKFYVLDMFPYPSGKGLHVGH PLGYIATDVVGRFQRMQGRNVLHALAYDAFGLPAEQYAVQTGQHPRITTEQNIATMRGQLRRLGLGHDDRRTFATTDPDY VRWTQWIFTQLFASFYDADAPRPDGGTGRARPIAELVAELDAGTRALPDGRVWTDLDAAARADHLDSVRLAYISNSPVNW APGLGTVLSNEEVTADGRSERGNFPVFQRNLRQWMLRITAYADRLVDDLELIEWPEKVKTMQRNWIGRSSGAQVRFVTDA GDLSVFTTRPDTLFGATFVAVAPEHPLLDALASEQWPEGTSEAWTGAAASPREAVTAYRRAASTKTELDRQTEGRDKTGV FTGAFATNPVTGARVPVFVADYVLMGYGTGAIMAVPGQDERDWEFATRFGLPIVRTVAPPEGWEGEAYPGEGPAINSAND EISLDGLGVVEAKAAIIAWLEAKGLGTGTVTYRLRDWLFSRQRYWGEPFPVVFDDDGRAHTLPDEMLPVELPDVPDYAPR TFDPQDADSEPEPPLARLPEWVDVELDLGDGVRRYRRETNTMPNWAGSCWYELRYLDPHDEKALVDPDIERYWMGPGAER PGGDPTDVAGGADLYVGGVEHAVLHLLYARFWHKVLYDLGHTASREPFHKLFNQGYIQAYAYADARGVYVPADEVHEEPG LDGETTYTWRGEPVVREYGKMGKSLKNMVTPDDMYAAYGADTFRVYEMSMGPLDQSRAWETRAVVGAQRFLQRLWRNVVD ETSGAVVVVEEPADDATRRLVARTIADVRTEYAAMRPNTAIAKLIALNNHLTTLAAVPREAVEPLVLMVAPVAPHIAEEL WARLGHPASLAHEPFPTADPALLVEETVTCVVQVAGKVRDRIEVPPAIGEAELRELALATAGVQRALDGRGVRTVIVRAP RLVNVVPA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-143 | 46 |
