Gene Information

Name : VCD_003554 (VCD_003554)
Accession : YP_002879280.1
Strain :
Genome accession: NC_012668
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 2834973 - 2836631 bp
Length : 1659 bp
Strand : +
Note : -

DNA sequence : 
ATGTGCTCACCGCTTAAGGAGATAAGAATGACAACCGATTTTACCCCTTGGCCAGAGGCACTTGCCGCTCAATACCGTCA
GTTAGGCTACTGGCAAGATAAAACCTTGCTCGATTACTTACAGCAAAGTGCTGAGCGTACCCCCAATGCGCTTGCGCTGG
TCGGTGATAATCAGCAGTGGCGTTACCAAGCCATGCTCGAACGTATTGAGCAGCTTGCTGCCGGATTTACCGAACTTGGG
CTAGGCTGTGGCGATAACGTAGTGCTGCAATTAGGCAATGTTGCGGAATTCTATTTATGCTTTTTCGCTTTGCTGCGCCA
AGGCATACGACCGATTCTGGCGCTCCCCGCTCACCGTTTAGCGGAAATTCGCTATTTTTGTCAGCACAGCCAAGCCAAAG
CTTACCTCATTGATGGCGCTCAGCGACCATTTGACTATCAAGCTTTGGCGCAAGAGCTGCTTGCTTGCTGCCCAACACTG
CAGACTGTGATTGTACGCGGCCAAACTCGAGTGACAGATCCAAAATTTATTGAACTGGCGAGTTGCTACTCGGCATCATC
TTGTCAAGCGAATGCCGACCCGAATCAAATCGCCTTTTTCCAACTTTCCGGTGGCACAACGGGCACGCCCAAGCTCATCC
CGCGTACCCACAATGATTACGCCTACAGCGTAACCGCCAGTGTCGAAATTTGCCGTTTTGATCAGCATACTCGCTATCTG
TGCGTACTGCCCGCGGCACATAACTTCCCTCTCAGCTCCCCCGGCGCACTCGGTGTTTTCTGGGCGGGTGGCTGCGTTGT
CCTCAGTCAAGATGCGTCACCCCAACACGCGTTTAAATTGATAGAACAGCATAAAATTACTGTTACCGCGTTGGTGCCGC
CTTTAGCACTACTCTGGATGGATCACGCAGAAAAAAGCACCTACGATCTCTCCTCATTGCACTTTGTGCAAGTAGGCGGG
GCAAAATTTAGTGAAGCGGCCGCAAGGCGTCTGCCGAAAGCGCTAGGCTGCCAATTGCAACAAGTGTTTGGAATGGCAGA
AGGCTTGGTCAATTACACTCGTTTGGATGACAGTGCGGAACTGATTGCTACAACTCAAGGTCGGCCTATCTCCGCTCACG
ATCAATTACTGGTGGTTGATGAGCAGGGTCAACCTGTCGCCAGCGGAGAAGAAGGGTATCTGTTAACCCAAGGTCCCTAT
ACGATTCGCGGTTACTATCGAGCTGATCAGCACAATCAACGAGCGTTCAATGCACAAGGTTTTTACATCACCGGCGATAA
AGTCAAACTCAGTAGCGAAGGTTACGTGATTGTCACCGGAAGGGCCAAAGATCAGATCAATCGTGGAGGGGAAAAGATTG
CCGCCGAAGAGGTGGAAAATCAGCTTTTACATCATCCAGCAGTGCATGATGCCGCTTTAATTGCCATCAGTGACGAATAC
CTAGGAGAGCGCAGTTGCGCGGTGATCGTACTCAAACCCGAGCAGTCGGTGAATACCATCCAGCTCAAACGTTTTTTACA
CCAAGCGGGGCTCGCCGATTACAAAATCCCAGATCAAATCCAATTTATCGATCAACTGCCCAAAACATCGGTTGGAAAAA
TCGATAAGAACGCGCTTCGTCGTCGATTTGACACGCTCGGCTTAGCGTTAATGTCGTGA

Protein sequence : 
MCSPLKEIRMTTDFTPWPEALAAQYRQLGYWQDKTLLDYLQQSAERTPNALALVGDNQQWRYQAMLERIEQLAAGFTELG
LGCGDNVVLQLGNVAEFYLCFFALLRQGIRPILALPAHRLAEIRYFCQHSQAKAYLIDGAQRPFDYQALAQELLACCPTL
QTVIVRGQTRVTDPKFIELASCYSASSCQANADPNQIAFFQLSGGTTGTPKLIPRTHNDYAYSVTASVEICRFDQHTRYL
CVLPAAHNFPLSSPGALGVFWAGGCVVLSQDASPQHAFKLIEQHKITVTALVPPLALLWMDHAEKSTYDLSSLHFVQVGG
AKFSEAAARRLPKALGCQLQQVFGMAEGLVNYTRLDDSAELIATTQGRPISAHDQLLVVDEQGQPVASGEEGYLLTQGPY
TIRGYYRADQHNQRAFNAQGFYITGDKVKLSSEGYVIVTGRAKDQINRGGEKIAAEEVENQLLHHPAVHDAALIAISDEY
LGERSCAVIVLKPEQSVNTIQLKRFLHQAGLADYKIPDQIQFIDQLPKTSVGKIDKNALRRRFDTLGLALMS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-95 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-95 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-95 47
ybtE CAA21394.1 - Virulence HPI Protein 3e-95 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-95 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 4e-95 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-95 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-95 46
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-95 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VCD_003554 YP_002879280.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-121 51
VCD_003554 YP_002879280.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 2e-119 48
VCD_003554 YP_002879280.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-103 44