Gene Information

Name : alr (VCD_001252)
Accession : YP_002876995.1
Strain :
Genome accession: NC_012668
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 251141 - 252268 bp
Length : 1128 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCTGGACCTGCATTTGACGATGAGTAATTCGATGAACTATATGAAGGCGGCCACCGCCTACATCAATTTAGAGGCGTT
GCAGCACAACTTGCAGCGCGTTAAGCAGCAAGCGCCAGAGAGTAAAATCATGGCGGTGGTGAAAGCCAATGGTTATGGAC
ACGGGCTGCGCCATATCGCACGTCACGCCCTTGGGGCGGATGCCTTTGGCGTGGCGCGCATTGAAGAGGCTTTACAGCTG
CGCGCCAGTGGCGTAGTGAAACCCATTTTGTTGCTTGAGGGATTTTATTCTCCCGGTGATTTGCCAGTATTGGTTACCAA
CAACATCCAAACCGTCGTACATTGTGAAGAGCAGTTACAAGCGCTGGAGCAAGCTCAGCTAGAGACTCCGGTCATGGTAT
GGCTGAAAGTCGACAGCGGGATGCATCGGCTAGGGGTTCGCCCTGAACAATATCAAGATTTCGTGGCTCGTTTGCACCAG
TGTGAGAATGTGGCTAAACCACTGCGTTACATGAGCCATTTCGGCTGTGCCGATGAGTTAGATAAATCGACGACGGTAGA
GCAAACAGAACTGTTTTTATCCCTGACGCAAGGCTGTCAGGGTGAGCGTTCGCTGGCCGCTTCTGCCGGATTATTAGCTT
GGCCGCAAAGCCAGCTTGAATGGGTAAGGCCGGGAATTATTATGTACGGCGTTTCTCCCTTTGTGGAAAAGAGCGCGGTT
CAGTTAGGTTACCAGCCAGTGATGACCTTAAAGTCGCACTTGATCGCTGTCCGCGAAGTGAAAGCGGGGGAGAGTGTCGG
TTATGGCGGTACTTGGACCAGCCAGCGAGATACCAAAATTGGTGTGATTGCGATTGGTTATGGTGATGGCTATCCACGCA
CTGCGCCGAATGGGACGCCAGTGGTTGTCAATGGGCGTCGGGTGCCGATTGCTGGGCGCGTATCTATGGATATGTTGACG
GTAGATTTAGGGCCGGATGCTTGCGATCGCGTCGGTGATGAAGCCATGCTGTGGGGTAATGAGCTGCCCGTAGAAGAAGT
GGCCGCACATATTGGTACGATAGGGTATGAGTTAGTGACGAAACTCACCTCGCGAGTGGAAATGTCTTATTATGGAGCAG
GCGTTTAG

Protein sequence :
MLDLHLTMSNSMNYMKAATAYINLEALQHNLQRVKQQAPESKIMAVVKANGYGHGLRHIARHALGADAFGVARIEEALQL
RASGVVKPILLLEGFYSPGDLPVLVTNNIQTVVHCEEQLQALEQAQLETPVMVWLKVDSGMHRLGVRPEQYQDFVARLHQ
CENVAKPLRYMSHFGCADELDKSTTVEQTELFLSLTQGCQGERSLAASAGLLAWPQSQLEWVRPGIIMYGVSPFVEKSAV
QLGYQPVMTLKSHLIAVREVKAGESVGYGGTWTSQRDTKIGVIAIGYGDGYPRTAPNGTPVVVNGRRVPIAGRVSMDMLT
VDLGPDACDRVGDEAMLWGNELPVEEVAAHIGTIGYELVTKLTSRVEMSYYGAGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 4e-55 43