Gene Information

Name : leuS (VCD_003381)
Accession : YP_002879111.1
Strain :
Genome accession: NC_012668
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2642346 - 2644982 bp
Length : 2637 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCCGAACCGAAAGACTTCGTTCCTACTGAACTCACAAATTCCAAGATGGATGTCATCGATGCAAGAGCAATACAACCC
GCAAGATATTGAACACAAAGTTCAACAGCACTGGGACAACAACAAAACCTTCGTTGTAAGTGAAGACCCAAATAAAGAAA
AATTCTACTGTCTTTCCATGTTCCCTTATCCAAGTGGCCGACTGCACATGGGTCACGTGCGTAACTACACCATCGGTGAT
GTAGTCTCTCGTTTCCAACGTCTGCAAGGCAAAAACGTACTGCAACCTATTGGTTGGGATGCTTTTGGTCTGCCTGCTGA
AAACGCAGCGGTAAAAAACAATACTGCGCCAGCACCTTGGACATACGAAAATATCGAATACATGAAAAACCAGCTCAAGC
TACTGGGTTTTGGTTATGACTGGAATCGTGAATTCGCGACTTGTCGCCCTGAGTACTACCGCTGGGAACAAGAGTTTTTC
ACTAAGCTGTTTGCAAAAGGCTTAGTGTACAAAAAAACCTCATCAGTTAACTGGTGTCCAAACGACCAAACGGTTCTGGC
TAACGAACAAGTGGAAGATGGTTGCTGCTGGCGTTGTGACACTCCGGTTGAGCAAAAAGAGATCCCACAGTGGTTTATTA
AGATCACCGCCTATGCTCAAGAGCTGCTTGACGATCTGGATAACCTAGACGGTTGGCCTGAAATGGTCAAAACCATGCAG
CGCAACTGGATTGGCCGCTCTGAAGGTGTGGAACTGAAATTTGCCGTTAAAGGTGAAAACACCGATCTTGAAGTGTACAC
CACGCGTCCAGATACTCTGATGGGGGTTACTTATGTCGGTATCGCTGCAGGCCACCCTCTAGCGACAAAAGCGGCAGCGA
ATAACCCAGCGCTCGCCGCCTTCATCGATGAATGTAAAAACACCAAGGTTGCAGAAGCTGAAATCGCGACCATGGAAAAG
AAAGGCATGGCGACAGGCCTGACGGCGATCCATCCTCTCAACGGCCGTGAAGTACCTATCTATATCGCGAACTTCGTGTT
GATGGATTACGGTACTGGTGCGGTAATGGCTGTGCCTGCGCACGACCAACGTGACTTTGAATTCGCGACCAAATATGGCC
TAGACATCATCCCTGTGATTAAGCCTGCCGATGGCAGCGAGCTGGATGTGTCTGAAGCGGCTTACACTGAAAAAGGTGTT
CTTTTCGCTTCTGGCGAATTTGATGGTTTGGATTTCCAAGCTGCCTTTAATGCGATTGCTGCCAAATTGGAAGCAGAAGG
CAAAGGTAAGAAAACCGTTAACTTCCGTCTGCGTGACTGGGGCGTGTCTCGTCAACGTTACTGGGGTGCTCCAATCCCAA
TGGTGACCACTGAAGATGGCCAAGTACACCCAGTACCAGCAGACCAACTGCCCGTTATCCTACCTGAAGATGTGGTGATG
GATGGCGTGACTAGCCCAATCAAAGCCGATAAAGAGTGGGCAAAAACCACCTTTAACGGTGAGCCAGCACTGCGTGAAAC
CGATACCTTCGACACCTTTATGGAGTCTTCATGGTACTACGCGCGTTACTGCTCACCACAAGCGGATGATATTTTAGATC
CAGAAAAAGCCAACTACTGGCTACCGGTTGATCAGTACATCGGTGGTATTGAACACGCGTGTATGCACTTGCTCTATTCA
CGCTTCTTCCACAAACTGCTGCGTGACGCGGGTTATGTGAAGAGTGATGAACCGTTCAAAAAACTCTTGTGTCAAGGCAT
GGTACTGGCAGATGCGTTCTACTACACCAATGACAAAGGTGGTAAAGAGTGGGTGTCGCCAACTGAGGTTAAAGTAGAAC
GTGATGGTAAAGGCCGCATCGTTTCTGCGGTGGATGCCACAGGCCGTCAAGTTGAACACTCAGGCATGATCAAAATGTCT
AAGTCGAAAAACAACGGTATCGACCCACAAGAGATGGTCGATAAATACGGCGCTGACACAGTACGTCTGTTCATGATGTT
TGCTTCACCAGCGGACATGACGTTGGAATGGCAAGAGTCTGGTGTGGAAGGTGCAAACCGCTTCCTGCGCCGCGTATGGA
AACTGGTGCGTGAGCACACTGAGCTCGGCCAAGCTCCCGCTTTAGATGCTTCAGCACTGAATGCAGACCAAAAAGCGCTG
CGCCGCGATGTGCACAAAACCATCGCTAAAGTGACGGATGACGTAGCACGTCGCCAAACGTTCAACACAGCGATTGCGGC
AATCATGGAGTTGATGAACAAGCTGACGAAAGCGCCGATGACCGAAGCGCAAGATCGCGCGATTCTGGATGAAGCACTCA
AAGCCATCACGCTCATGCTTTACCCAATCACACCGCATATCTGTTTCGAAATGTGGGTGGCACTGGGTCAAAGCAATATC
GATACGGCAAGCTGGCCGACGTACGATGAAGCCGCACTGGTCGAAGATGAAAAGCTGATCGTGCTGCAAGTCAACGGCAA
ACTGCGCGGTAAACTCACTGTCGCTGCCGATGCTACTCAACAACAGGTTGAAGCGCTCGGTATGCAAGATGAAAACGTAC
AGAAGTTCATTGATGGCCTCACCGTACGTAAAGTGATTTACGTACCGGGCAAACTGCTGAACATCGTTGCCAACTAA

Protein sequence :
MPNRKTSFLLNSQIPRWMSSMQEQYNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGRLHMGHVRNYTIGD
VVSRFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNREFATCRPEYYRWEQEFF
TKLFAKGLVYKKTSSVNWCPNDQTVLANEQVEDGCCWRCDTPVEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQ
RNWIGRSEGVELKFAVKGENTDLEVYTTRPDTLMGVTYVGIAAGHPLATKAAANNPALAAFIDECKNTKVAEAEIATMEK
KGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPVIKPADGSELDVSEAAYTEKGV
LFASGEFDGLDFQAAFNAIAAKLEAEGKGKKTVNFRLRDWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILPEDVVM
DGVTSPIKADKEWAKTTFNGEPALRETDTFDTFMESSWYYARYCSPQADDILDPEKANYWLPVDQYIGGIEHACMHLLYS
RFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVERDGKGRIVSAVDATGRQVEHSGMIKMS
KSKNNGIDPQEMVDKYGADTVRLFMMFASPADMTLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKAL
RRDVHKTIAKVTDDVARRQTFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWVALGQSNI
DTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDENVQKFIDGLTVRKVIYVPGKLLNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-153 44