Gene Information

Name : hemC (PFLU5934)
Accession : YP_002875420.1
Strain : Pseudomonas fluorescens SBW25
Genome accession: NC_012660
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 6492274 - 6493215 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCCTCTCGCGAAATCCGCATCGCCACCCGTAAAAGCGCCCTGGCCTTGTGGCAGGCCGAATACGTCAAAGCACGCCT
GGAGCAGGCTCACCCTGGCCTCAAGGTGTCCCTGGTGCCCATGGTCAGTCGCGGTGACAAACTGCTCGACTCGCCACTGT
CGAAAATCGGCGGCAAGGGCCTGTTTGTCAAAGAGCTGGAAACCGCGCTGCTGGAAAACGAAGCGGACATTGCCGTGCAC
TCGATGAAAGACGTGCCCATGGACTTCCCCGAAGGCTTGGGCCTGTTTTGCATCTGCGAGCGTGAAGACCCGCGTGATGC
CTTCGTTTCCAATACTTACGCGTCTCTGGATGCGCTGCCTTTGGGCAGCATCGTCGGTACGTCGAGCCTGCGCCGCCAGG
CACAGTTGCTGACCCGCCGCCCGGACCTGCAGATCCGCTTCCTGCGCGGCAACGTCAACACCCGCCTGGCGAAGCTGGAT
GCGGGTGAATATGACGCGATCATCCTCGCAGCGGCTGGGCTGATCCGTCTGGGTTTCGAAGACCGTATCACTTCGGCCAT
CAGCGTCGAGGACAGCCTGCCTGCCGGTGGGCAGGGCGCCGTCGGCATTGAATGCCGTACCGCCGACAGTGATATCCACG
CCCTGCTCAAACCCCTGGATCACCACGACACTGAAGTGCGCGTCACGGCTGAGCGTGCCCTGAACAAGCACCTCAACGGT
GGCTGCCAAGTGCCGATCGCCTGCTACGCCGTGCTCGAAGGTGAAAACCTGTGGTTGCGGGGCTTGGTCGGAGACCCGGA
AGGCGGCAACCTGCTGACCGCCGAGGTCCGTGGTCCGCAGTGTGACGCTACGGCGTTGGGTATCCAGGTGGCGCAAGCGC
TGCTGGATAAGGGCGCTGGTGCGATTCTGCAGAAAGTCTACGGCGAGGCCGGCCCGCAGTGA

Protein sequence :
MSSREIRIATRKSALALWQAEYVKARLEQAHPGLKVSLVPMVSRGDKLLDSPLSKIGGKGLFVKELETALLENEADIAVH
SMKDVPMDFPEGLGLFCICEREDPRDAFVSNTYASLDALPLGSIVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLD
AGEYDAIILAAAGLIRLGFEDRITSAISVEDSLPAGGQGAVGIECRTADSDIHALLKPLDHHDTEVRVTAERALNKHLNG
GCQVPIACYAVLEGENLWLRGLVGDPEGGNLLTAEVRGPQCDATALGIQVAQALLDKGAGAILQKVYGEAGPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-76 60
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-76 60