Gene Information

Name : leuS (PFLU5410)
Accession : YP_002874908.1
Strain : Pseudomonas fluorescens SBW25
Genome accession: NC_012660
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 5943037 - 5945643 bp
Length : 2607 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCACGAACACTACCAGCCCCGTGAAATAGAAAATGCCGCCCAATCCTTCTGGGACGAGCAGAAGTCCTTTGAAGTCAG
TGAACAGCCAGGCAAGGAGACATTCTATTGCCTATCGATGTTCCCTTACCCCAGCGGCAAGCTGCACATGGGGCACGTGC
GCAACTACACCATCGGTGACGTGATTTCGCGCTACCAGCGCATGCAAGGCAAGAACGTCCTGCAACCCATGGGTTGGGAT
GCCTTCGGCATGCCGGCGGAAAACGCCGCGATGAAAAACAACGTGGCCCCCGCCAAGTGGACCTACGAAAACATCGCCTA
CATGAAGAACCAGCTGCGCAGCCTGGGCCTGGCGGTGGATTGGTCACGCGAAGTGACCACCTGCAAGCCGGACTACTACC
GCTGGGAACAATGGCTGTTCACTCGCCTGTTCGAAAAAGGCGTGATCTACAAAAAAAGCGGCACCGTGAACTGGGACCCG
ATCGACCAGACCGTCCTGGCCAACGAGCAAGTGATCGACGGGCGCGGCTGGCGTTCCGGCGCGCTGATCGAAAAGCGCGA
AATCCCGATGTACTACTTCAAGATCACCGCCTACGCGGATGAACTCTTGTCGAGCCTCGACGACCTGCCGGGCTGGCCCG
AACAGGTCAAGACCATGCAACGCAACTGGATCGGCAAGTCCAAGGGCATGGAAGTGCAGTTCCCGTACAACGTCGACTCG
ATCGGCGAAGCGGGCGCACTCAAAGTCTTCACCACCCGTCCGGATACCCTGATGGGCGCGACCTACGTCGCCGTGGCCGC
CGAACACCCGCTGGCCACCCAGGCCGCCCAGAACAACCCTGAGCTGCAAGCGTTCATCGCCGAATGCAAAGGCGGCAGCG
TGGCCGAAGCCGACGTCGCCACCCAGGAGAAAAAAGGCCTGCCGACCGGGCTGTTCGTCGAGCACCCACTCACCGGTGAA
AAGCTGCCGGTCTGGGTCGCCAACTACGTGCTGATGCACTATGGCGATGGCGCAGTCATGGCTGTGCCGGCCCACGACGA
ACGCGATTTCGAATTCGCCACTAAGTACAGCCTGCCGATCAAATCCGTGGTGCGCACCAGCTCGGGCGACACCAACCCGG
CCCCGTGGCAAGACGCCTACGGCGAGCACGGTGAGCTGATCAACTCCGGCGAGTTTGACGGCCTGGACTTCCAGGGCGCC
TTCGACGCCATCGAAGTCGCACTGATCAAGAAAAACCTCGGTGCCTCGCGCACCCAGTTCCGCCTGCGCGACTGGGGCAT
CAGCCGCCAGCGCTACTGGGGCTGCCCGATCCCGATCATCCACTGCGAAAGCTGTGGCGACGTGCCAGTACCGGAAGACC
AATTGCCGGTCGTCCTGCCGGAAGACGTGGTGCCGGACGGCGCTGGCTCGCCACTGGCACGCATGCCCGAGTTCTACGAA
TGCAGCTGCCCGAAATGCGGCCAGCCTGCCAAGCGTGAAACCGACACCATGGACACCTTCGTCGAGTCCTCGTGGTACTA
CGCCCGCTACGCCTCGCCGCACTATGAAGGCGGCCTGGTGGAAAAATCCGCGGCCGACCATTGGTTGCCGGTGGACCAGT
ACATTGGCGGTATCGAACACGCCATCCTTCACCTGCTGTACGCGCGTTTCTTCCACAAGCTGATGCGTGACGAAGGCCTG
GTGAGTTCCAATGAGCCGTTCAAGAACCTGCTGACCCAGGGCATGGTAGTCGCCGAGACTTACTATCGCCGTGAAGCCAA
TGGTGCGTACACCTGGTTCAACCCGGCCGACGTCGAGCTCGAGCGCGACAGCAAAGCCAAGGTCATCAGCGCCAAACTGA
TCGCCGACGGCCTGCCGGTGGAAATCGGCGGCACCGAGAAGATGGCCAAGTCGAAGAACAACGGCGTCGACCCACAGTCG
ATGATCGATCAGTTCGGCGCCGACACCTGCCGCCTGTTCATGATGTTCGCCTCGCCGCCCGACATGAGCGCCGAATGGTC
CGACTCCGGCGTCGAAGGCTCGCACCGCTTCCTCAAGCGCGTCTGGCGCCTGGCGCACGCCCACATCAGCCAGGGCCTGC
CAGGCAAACTGGACGTGGCCGCATTGAGCGACGAGCAGAAACTCATTCGCCGCAGCATCCACCTGGCCATCAAGCAAGCC
AGCCAGGACGTGGGCCAGAACCACAAATTCAACACCGCCATCGCCCAAGTGATGACGCTGATGAACGTGCTGGAAAAAGC
GCCACAAGCCACTGAACAGGATCGTGCGCTGGTGCAGGAAGGCCTGGAAACGGTCACCCTGCTGCTGGCCCCGATCACGC
CGCACATCAGCCACGACCTGTGGAACCGCCTGGGCCACAGCGACGCCGTCATTGATGCGCGCTGGCCGGTGCAGGATGAC
AGCGCCCTGGTACAGGACACGCTGCAACTGGTGATCCAGGTCAACGGCAAACTGCGCGGCCAGATCGATATGCCGGCCAC
CGCCAGCCGCGAAGACGTCGAGGCGGCTGCCCGCGTCAACGAAAACGTGCTGCGCTTTACCGAAGGCCTGACGATCCGCA
AAGTGATCGTCGTGCCTGGCAAACTGGTCAATATCGTCGCTAGCTAA

Protein sequence :
MHEHYQPREIENAAQSFWDEQKSFEVSEQPGKETFYCLSMFPYPSGKLHMGHVRNYTIGDVISRYQRMQGKNVLQPMGWD
AFGMPAENAAMKNNVAPAKWTYENIAYMKNQLRSLGLAVDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYKKSGTVNWDP
IDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYADELLSSLDDLPGWPEQVKTMQRNWIGKSKGMEVQFPYNVDS
IGEAGALKVFTTRPDTLMGATYVAVAAEHPLATQAAQNNPELQAFIAECKGGSVAEADVATQEKKGLPTGLFVEHPLTGE
KLPVWVANYVLMHYGDGAVMAVPAHDERDFEFATKYSLPIKSVVRTSSGDTNPAPWQDAYGEHGELINSGEFDGLDFQGA
FDAIEVALIKKNLGASRTQFRLRDWGISRQRYWGCPIPIIHCESCGDVPVPEDQLPVVLPEDVVPDGAGSPLARMPEFYE
CSCPKCGQPAKRETDTMDTFVESSWYYARYASPHYEGGLVEKSAADHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGL
VSSNEPFKNLLTQGMVVAETYYRREANGAYTWFNPADVELERDSKAKVISAKLIADGLPVEIGGTEKMAKSKNNGVDPQS
MIDQFGADTCRLFMMFASPPDMSAEWSDSGVEGSHRFLKRVWRLAHAHISQGLPGKLDVAALSDEQKLIRRSIHLAIKQA
SQDVGQNHKFNTAIAQVMTLMNVLEKAPQATEQDRALVQEGLETVTLLLAPITPHISHDLWNRLGHSDAVIDARWPVQDD
SALVQDTLQLVIQVNGKLRGQIDMPATASREDVEAAARVNENVLRFTEGLTIRKVIVVPGKLVNIVAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 5e-149 42