Gene Information

Name : sph (BAA_0761)
Accession : YP_002865273.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Virulence
Product : sphingomyelin phosphodiesterase C
Function : -
COG functional category : R : General function prediction only
COG ID : COG3568
EC number : 3.1.4.12
Position : 695970 - 696971 bp
Length : 1002 bp
Strand : +
Note : identified by match to protein family HMM PF03372; match to protein family HMM TIGR03395

DNA sequence :
GTGAAAGGTAAATTGCTAAAAGGTGTACTTAGCTTTGGGATTGGTTTAGGAGTTTTATACGGAGGATCCTCAGCTCAAGC
AGATACGTCTACAGATCAAAACAATACTTTGAAAGTGATGACGCATAACGTGTACATGCTATCAACTAACTTATATCCGA
ATTGGGGACAAAGTGAGCGTGCTGATTTAATTGGGGCGGCAGATTATATTAAGAATCAAGACGTTGTTATATTAAATGAA
GTGTTTGATAATAGTGCTTCAGATCGCCTTTTAGGAAATTTGAAGAAAGAATACCCAAATCAAACAGCTGTATTAGGTCG
TAGCAACGGAAATGAATGGGATAAAACGTTAGGTAGCTATTCATCTGCAACTCCTGAAGATGGAGGCGTTGCAATCGTTA
GCAAATGGCCGATCGTTGAAAAGGTTCAATATGTATTTGCAAATGGATGTGGACCAGATAATTTATCGAATAAAGGATTT
GTATACACGAAAATTAAGAAAAATGATCGTTTCGTTCATGTAATTGGGACGCATTTGCAGGCTGAAGATAGTATGTGCGG
AAAAACTTCACCTGCATCTGTACGTACAAACCAGTTAAAAGAAATTCAAGATTTTATTAAAAATAAAAATATACCAAATG
ACGAGTACGTCCTATTTGGTGGTGATATGAATGTGAATAAAATAAATGCTGAGAACAATAGTGACTCAGAATACGCATCA
ATGTTCAAAACATTGCACGCTTCTATTCCATCTTATACAGGACATACAGCAACTTGGGATGCAACGACAAACAGTATTGC
AAAATATAATTTCCCTGATAGCCCTGCCGAGTATTTAGATTATATTATTGCAAGTAAGGACCATGCGAATCCGTCATTTA
TAGAGAATAAAGTATTACAACCGAAATCTCCACAGTGGACTGTTACATCATGGCTCAAAAAATATACATATAATGATTAT
TCTGATCATTATCCAGTCGAGGCGACTATTTCTATGAAGTAG

Protein sequence :
MKGKLLKGVLSFGIGLGVLYGGSSAQADTSTDQNNTLKVMTHNVYMLSTNLYPNWGQSERADLIGAADYIKNQDVVILNE
VFDNSASDRLLGNLKKEYPNQTAVLGRSNGNEWDKTLGSYSSATPEDGGVAIVSKWPIVEKVQYVFANGCGPDNLSNKGF
VYTKIKKNDRFVHVIGTHLQAEDSMCGKTSPASVRTNQLKEIQDFIKNKNIPNDEYVLFGGDMNVNKINAENNSDSEYAS
MFKTLHASIPSYTGHTATWDATTNSIAKYNFPDSPAEYLDYIIASKDHANPSFIENKVLQPKSPQWTVTSWLKKYTYNDY
SDHYPVEATISMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 8e-71 59
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 7e-71 59
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 5e-71 59
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 6e-77 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sph YP_002865273.1 sphingomyelin phosphodiesterase C VFG1798 Protein 2e-78 58
sph YP_002865273.1 sphingomyelin phosphodiesterase C VFG0674 Protein 3e-77 55