Gene Information

Name : phoP (BAA_4844)
Accession : YP_002868868.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Resistance
Product : DNA-binding response regulator PhoP
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 4397007 - 4397726 bp
Length : 720 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence : 
ATGAACAATCGTATTTTAGTAGTTGATGATGAGGAGTTTATCTTAACTTTAATCGAATTTAATTTACAACAAGCTGGTTT
TGAAGTAATAACAGCGATGGATGGTGAGATGGCGCTGCAAAAAGCGACAACAGAACGTCCAGATTTAATTATATTAGATT
TAATGCTTCCAAAAATGGATGGTATGGAAGTATGTAAAGAATTACGATTGCAGCGCGTTATGACGCCAATTTTAATGTTA
ACAGCAAAAGATGATGAGTTTGATAAGGTGCTAGGTCTTGAACTTGGGGCGGATGATTATATGACGAAGCCATTTAGCCC
AAGGGAAGTTGTTGCACGTGTGAAGGCAATTTTACGCCGTACGAAATTACAACAAGAAGAGCAAGTTACAGAAACGTCAG
ATGAAGAGAGCATCACAATTGCTGAACTTAAAATTTTGCCGGAATTTTATGAAGCTTATTTCCAAGGAAGAAAGCTTGAA
TTAACACCAAAAGAATTTGAACTACTTGTTTATCTTGCGAAAAATAAAAGTCGCGTGTTGACACGTGATCAATTATTAAG
TGCTGTATGGAACTATGATTTTGCTGGTGATACACGAATTGTTGACGTTCATATTAGCCATTTGCGCGATAAAATTGAAC
AAAATACGAAAAAACCGACGTACATTAAAACGATACGTGGTTTAGGATATAAATTAGAGGAGCCAAAAGGGGATGAATAA

Protein sequence : 
MNNRILVVDDEEFILTLIEFNLQQAGFEVITAMDGEMALQKATTERPDLIILDLMLPKMDGMEVCKELRLQRVMTPILML
TAKDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTKLQQEEQVTETSDEESITIAELKILPEFYEAYFQGRKLE
LTPKEFELLVYLAKNKSRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLRDKIEQNTKKPTYIKTIRGLGYKLEEPKGDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 4e-34 41
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_002868868.1 DNA-binding response regulator PhoP HE999704.1.gene2815. Protein 5e-73 66
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_007793.3914279.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_007622.3794472.p0 Protein 7e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_002745.1124361.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_009782.5559369.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_002951.3237708.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_002952.2859905.p0 Protein 1e-74 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_003923.1003749.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_002758.1121668.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_009641.5332272.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_013450.8614421.p0 Protein 6e-75 64
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_012469.1.7686381. Protein 1e-62 56
phoP YP_002868868.1 DNA-binding response regulator PhoP AE016830.1.gene1681. Protein 8e-64 55
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_012469.1.7685629. Protein 5e-54 53
phoP YP_002868868.1 DNA-binding response regulator PhoP BAC0197 Protein 1e-28 44
phoP YP_002868868.1 DNA-binding response regulator PhoP AE000516.2.gene3505. Protein 5e-41 44
phoP YP_002868868.1 DNA-binding response regulator PhoP CP001918.1.gene5135. Protein 1e-31 44
phoP YP_002868868.1 DNA-binding response regulator PhoP FJ349556.1.orf0.gene Protein 2e-39 43
phoP YP_002868868.1 DNA-binding response regulator PhoP CP001485.1.gene721.p Protein 7e-36 43
phoP YP_002868868.1 DNA-binding response regulator PhoP CP004022.1.gene3215. Protein 2e-36 43
phoP YP_002868868.1 DNA-binding response regulator PhoP CP000647.1.gene4257. Protein 1e-34 43
phoP YP_002868868.1 DNA-binding response regulator PhoP BAC0533 Protein 1e-34 43
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_014475.1.orf0.gen Protein 2e-39 42
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_005054.2598277.p0 Protein 2e-39 42
phoP YP_002868868.1 DNA-binding response regulator PhoP AF155139.2.orf0.gene Protein 2e-38 42
phoP YP_002868868.1 DNA-binding response regulator PhoP CP001138.1.gene4273. Protein 8e-34 42
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_002695.1.915041.p Protein 2e-33 42
phoP YP_002868868.1 DNA-binding response regulator PhoP CP000034.1.gene3834. Protein 2e-33 42
phoP YP_002868868.1 DNA-binding response regulator PhoP CP000034.1.gene2186. Protein 1e-36 42
phoP YP_002868868.1 DNA-binding response regulator PhoP BAC0596 Protein 8e-36 42
phoP YP_002868868.1 DNA-binding response regulator PhoP CP001918.1.gene3444. Protein 4e-36 42
phoP YP_002868868.1 DNA-binding response regulator PhoP NC_002695.1.916589.p Protein 1e-36 42
phoP YP_002868868.1 DNA-binding response regulator PhoP BAC0039 Protein 1e-36 42
phoP YP_002868868.1 DNA-binding response regulator PhoP CP001138.1.gene2239. Protein 8e-36 42
phoP YP_002868868.1 DNA-binding response regulator PhoP AF310956.2.orf0.gene Protein 2e-34 41
phoP YP_002868868.1 DNA-binding response regulator PhoP U35369.1.gene1.p01 Protein 1e-33 41
phoP YP_002868868.1 DNA-binding response regulator PhoP AE016830.1.gene2255. Protein 1e-33 41
phoP YP_002868868.1 DNA-binding response regulator PhoP AF162694.1.orf4.gene Protein 2e-35 41
phoP YP_002868868.1 DNA-binding response regulator PhoP CP004022.1.gene1676. Protein 2e-32 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_002868868.1 DNA-binding response regulator PhoP VFG1389 Protein 7e-36 46
phoP YP_002868868.1 DNA-binding response regulator PhoP VFG1386 Protein 2e-40 43