Gene Information

Name : polA (BAA_4842)
Accession : YP_002868866.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 4392331 - 4394964 bp
Length : 2634 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
TTGGAAAAAAAGGTCGTATTAGTAGATGGTAATAATATCGCGTATCGTGCTTTCTTTGCACTACCGCTTTTAAATAACGA
CAAAGGTATACATACGAACGCAATTTACGGTTTTACAATGATGTTAATGAGAATATTAGAGGAAGAAAAACCGACGCATA
TGTTAGTAGCATTTGATGCGGGGAAAACGACATTCCGTCATAAAACATATAGTGAGTATAAAGGGGGACGTCAAAAGACT
CCGCCTGAGTTATCAGAGCAATTCCCGTTTATTCGTGAGATGCTTGATGCATTCAATGTACCACGTTATGAATTAGAAAA
TTATGAAGCGGATGACATTATGGGAACGCTAGCGAAAGAAGCGAGTGAACAAGGCGCAAGTGTAAAAGTTATTTCAGGAG
ATAAAGACTTACTTCAACTTGTTTCTGATAACACGCTTGTATGTATTCCTCGAAAAGGGATTACGGAAGTAGACGAATAT
ACGAAAGAAGCTTTATTTGAAAAATACAGCTTATCACCAAAGCAAATTATCGATATGAAAGGTTTAATGGGAGACCAATC
AGATAATATTCCAGGTGTACCAGGAGTTGGTGAAAAAACTGCGATTAAATTGTTAACACAGTTTGGAACGGTTGAAGAAG
TGTATGAAAATATAGATCAAGTAAGCGGGAAGAAATTAAAAGAAAAGCTGGAAGCAAATAAAGACCAAGCTCTTATGAGT
AAAGATCTTGCAACCATTATTACAGACGCACCGATTACTGTGAATGTGGATGATATGGAGTATAAAGGATATGAAGCAAG
TGATGTCATTCCAATGTTCGAGAATTTAGGATTTACATCTCTTTTAAACAAATTAGGTGTTACGCCAGAAGAAACAGCTC
CGGCTGAATTAGATGATATTACATTTGATATTGTAGAAGAAGTTACAGAAGAAATGCTTCAGCAAGATAGTGCGCTTATC
GTTGAAGTACAAGAAGATAACTATCATAAAGCAGACATTCAAGGTTTCGGTATTCAAAATGAAAATGGATGTTACTTTAT
TCAGACAGACATTGCACTTAAATCAGATGCTTTTAAAGAGTGGCTTGCAGATGGAGAAATGAGAAAGTATACATTTGATG
CGAAGCGTGCGATCGTTGCGCTGAAATGGAACGGTATAGATATGCAAGGGATTGACTTTGATCTATTAATCGCTGCTTAC
TTACTTGATCCGGCTGATACAGATAAAGATTTCCGTACTGTAGCGAAAATGAAAGAAACGCATGCTGTGAAATCTGATGA
AGAAGTTTACGGAAAAGGTGCGAAGCGTGCTGTTCCAGAGTTAGAGATAGTAGCGGAGCATGTAGCTCGTAAAGTGCATG
TATTATATGATGTAAAGCAAACATTTGTTGAAGAGTTAGAAAAGAATGAGCAATATGAACTGTTTACAGAGTTGGAATTA
CCACTTGCACGTGTATTAGCTGATATGGAAGTAAAAGGTGTAAAAGTTGATACAGAACGTCTTCGTAATATGGGAGAAGA
ACTTGCAGGTAGATTAAAGGAAATGGAACAGGAAATTTATAAGCTGGCGGGAACAGAATTTAATATTAATTCACCGAAGC
AGCTTGGTGTGATTCTGTTTGAGAATTTAAACTTACCGGTTATTAAGAAGACGAAAACAGGTTATTCTACATCAGCAGAT
GTATTAGACAAGCTGATGGATCACCATGAAATTATTCCAAACATTTTACATTACCGTCAATTAGGGAAACTCAATTCAAC
TTATATTGAAGGTTTATTAAAAGTTGTACATGAAGATTCATCTAAAATTCATACTCGCTTCAATCAAGTATTAACGCAAA
CAGGTCGATTAAGTTCAACGGATCCAAACTTGCAAAATATCCCGATTCGATTAGAAGAAGGAAGAAAGATTCGTCAGGCA
TTCGTTCCATCAGAAGAAGGATGGATTATGTACGCGGCCGATTATTCACAAATTGAACTTCGTGTATTAGCTCATATTGC
CAATGATAAAGGGCTAGTTGAAGCGTTCCAACATGACATGGATATTCATACAAAAACAGCGATGGATGTATTTGGCGTTG
AAAAAGATGAAGTAACTTCAAATATGAGACGACAAGCGAAAGCTGTTAACTTCGGAATTGTGTATGGTATTAGTGATTAT
GGTCTTTCACAAAACTTAGGAATTACAAGAAAAGCAGCAGCGGAATTTATTGAAAAGTATTTAGAAAGTTTCCCTGGTGT
ACAAGAATATATGGATGACATCGTAAAAGATGCGAAGCAAAAAGGATATGTGGCTACATTATTAAATCGTCGCCGTTACA
TTCCGGAAATTACGAGTCGTAATTTCAACTTGCGTAGCTTTGCTGAGCGTACAGCTATGAATACACCAATTCAAGGTACT
GCAGCAGATATTATTAAAAAAGCGATGATTATTATGGCAGATCGTTTAGAAGAAGAAGGATTACAAGCGCGTCTTCTTCT
GCAAGTACACGATGAATTAATATTTGAGGCACCAAAAGAAGAAGTTGAAAAATTAGAGAAGCTTGTACCAGAAGTAATGG
AGCATGCAATTGAACTGGCAGTTCCACTGAAAGTTGATTATTCTTACGGTCCAACTTGGTACGACGCAAAATAA

Protein sequence :
MEKKVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAFDAGKTTFRHKTYSEYKGGRQKT
PPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLAKEASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEY
TKEALFEKYSLSPKQIIDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQALMS
KDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAELDDITFDIVEEVTEEMLQQDSALI
VEVQEDNYHKADIQGFGIQNENGCYFIQTDIALKSDAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAY
LLDPADTDKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELEKNEQYELFTELEL
PLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQLGVILFENLNLPVIKKTKTGYSTSAD
VLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQA
FVPSEEGWIMYAADYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKDEVTSNMRRQAKAVNFGIVYGISDY
GLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRRYIPEITSRNFNLRSFAERTAMNTPIQGT
AADIIKKAMIIMADRLEEEGLQARLLLQVHDELIFEAPKEEVEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 51