Gene Information

Name : BAA_0474 (BAA_0474)
Accession : YP_002865024.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Resistance
Product : heavy metal-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 428760 - 430685 bp
Length : 1926 bp
Strand : -
Note : identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525

DNA sequence :
ATGAACTCAGAAGTAAAAACATTACAAGTACAAAAATCTATTTCTCATCCCTCTTTATGGGATACGTTAAAGAAACATTA
TGAACTTATATTTGCAATCACATCTGGTATTTTCATTTTAGCTGGTTGGTTATTCACAAAGAACGATGTAATGAATGTAG
GCATTACTTGCTATATCCTTGCTTATATAGTTGGTGGATATGCAAAAGCAAAAGAAGGTATTGAAGATACAATTGAGGAG
AAAGAGCTAAATGTCGAAATGCTTATGCTCATTGCTGCTATCGGTGCTGCAATGATTGGCTACTGGGCAGAAGGCGCCAT
TTTAATCTTTATCTTCGCACTAAGCGGTGCGATGGAATCTTATACATTAAGTAAAAGTCAAAAAGAAATTTCAGCGCTTC
TTGATCTACAACCGGAAGAAGCATTACGTATTTCAAATGGAACTGAAGAACGTGTTCCTGTTGGACGATTACAAATTAAC
GACATTATTTTAATTAAGCCAGGTGAGCGCGTTCCTGCTGACGGTACGATTCATAGCGGTGAAACAAATATCGATGAGGC
TGCGATTACTGGTGAACCTATTCCAAATGAAAAAAAACATGGTGATGAAGTATTTGCTGGTACTGTAAATTTACGCGGTG
CTATCGAAGTTAAAATTACGAAGCCGAGTGATCAAACATTATTCCAAAAGATTATCCGTCTCGTTCAAAGTGCACAAAGT
GAAAAATCACCATCACAACTATTCATCGAAAAGTTTGAAGGCACATATGTAAAAGGTGTACTACTCGTTGTTACGCTTAT
GATGTTCGTCCCTCATTTCTTACTGGATTGGAGCTGGAATGAAACGTTTTATCGCGCTATGATCTTACTTGTAGTCGCAT
CTCCTTGTGCACTCGTTGCTGCCATTACACCAGCAACATTATCTGCAATTTCTAACGGAGCAAGAAACGGTATTCTCTTT
AAAGGTGGCATACATTTAGAACGCCTCGCTTCCGTAAAAGCGATTGCCTTTGATAAAACGGGAACATTAACAGAAGGTAA
ACCTACCGTAACAGATGTATATGTTCGAGAAAATATGACAGAAAAAGAAGTACTTTCTATTACAGCAGCAATTGAAAGTC
ACTCTACACATCCTTTAGCTGAATCTATTGTGAAATATGCACAACATACGTATGATATTACATTAAAAAAACCAGAAAAT
GTTGAAGATGTAACTGGTTTTGGGCTAAAAGGAATATTTGAAAGCAAAGCTTATAAAATAGGTAAAGCTGATTTTATCGG
TGAAGAAACAAAGACATTTCATAATGGTGTTTCTGCCTCACTTGAAAAAGAAGGTAAAACTGTCGTTTATATTAGTGATG
AAGAAGGTATTCTTGGACTTATCGCTTTAAAAGATACACTTCGCCAAGAAACAATAGCTGCTATTCGTGAACTACAAAGT
ATCGGTGTCGAAGCAATTATGATTACTGGTGATAATGAAGAAACAGCAAAAGCAATTGCCTCTGAAAGTAATATAAAGGA
ATATTACGCATCATGCTTACCAGAAACAAAAGTGGAAACGATTAAAAAGCTAAAAGAAAAATACGGGACAGTAGCAATGG
TCGGAGATGGTATAAATGATGCTCCTGCACTCGCTACTGCTAGCATTGGTGTAGCAATGGGAGAAGGAACAGACGTAGCT
TTAGAAACTGCAGACGTTGTACTTATGAAGAACGAGTTATCTCGACTTTCCCAAGCGATCCGTTTATCAAAACGAATGAA
CCGTATTGTAAAGCAAAACGTAATCTTTTCACTAGCTGTAATTGCAATGCTAATTTGTTCCAACTTCTTGCAATTTTTAG
CTCTTCCATTCGGTGTTATTGGGCATGAAGGAAGTACGATTCTTGTTATTTTAAACGGGTTACGATTATTAAAAGGAAAC
AATTAA

Protein sequence :
MNSEVKTLQVQKSISHPSLWDTLKKHYELIFAITSGIFILAGWLFTKNDVMNVGITCYILAYIVGGYAKAKEGIEDTIEE
KELNVEMLMLIAAIGAAMIGYWAEGAILIFIFALSGAMESYTLSKSQKEISALLDLQPEEALRISNGTEERVPVGRLQIN
DIILIKPGERVPADGTIHSGETNIDEAAITGEPIPNEKKHGDEVFAGTVNLRGAIEVKITKPSDQTLFQKIIRLVQSAQS
EKSPSQLFIEKFEGTYVKGVLLVVTLMMFVPHFLLDWSWNETFYRAMILLVVASPCALVAAITPATLSAISNGARNGILF
KGGIHLERLASVKAIAFDKTGTLTEGKPTVTDVYVRENMTEKEVLSITAAIESHSTHPLAESIVKYAQHTYDITLKKPEN
VEDVTGFGLKGIFESKAYKIGKADFIGEETKTFHNGVSASLEKEGKTVVYISDEEGILGLIALKDTLRQETIAAIRELQS
IGVEAIMITGDNEETAKAIASESNIKEYYASCLPETKVETIKKLKEKYGTVAMVGDGINDAPALATASIGVAMGEGTDVA
LETADVVLMKNELSRLSQAIRLSKRMNRIVKQNVIFSLAVIAMLICSNFLQFLALPFGVIGHEGSTILVILNGLRLLKGN
N

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 5e-108 43
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 4e-108 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-97 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-97 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BAA_0474 YP_002865024.1 heavy metal-transporting ATPase BAC0092 Protein 1e-132 47