Gene Information

Name : BAA_4620 (BAA_4620)
Accession : YP_002868661.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 4179225 - 4180358 bp
Length : 1134 bp
Strand : -
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGAGCAAAGACAAAGTTAATTCATGGTATTCGCATAGGAGAACCTTCAACTGGATCTGTAAATGTACCGATTTATCA
AACGAGTACGTACAAACAAGAAGCAGTTGGTAAGCATCAAGGATATGAATATTCACGTACAGGAAACCCAACACGTGCAG
CTTTAGAAGAAATGATTGCTGTATTAGAAAACGGTCATGCTGGTTTTGCATTTGGCTCAGGAATGGCGGCTATTACAGCT
ACGATTATGTTGTTCTCAAAAGGTGACCACGTTATTTTAACAGATGATGTGTATGGTGGAACGTACCGCGTGATTACGAA
AGTATTAAACCGCTTCGGTATTGAGCATACATTTGTAGATACAACAAACTTAGAGGAAGTCGAAGAAGCGATTCGTCCAA
ATACGAAAGCAATTTATGTAGAAACACCAACGAATCCATTACTAAAAATTACTGATATTAAAAAAATATCTACTCTTGCT
AAAGAGAAAGGTTTATTAACAATTATTGATAACACATTCATGACGCCATATTGGCAGTCGCCGATCTCTTTAGGAGCAGA
TATTGTACTTCATAGTGCAACGAAATATTTAGGAGGTCATAGTGACGTAGTTGCAGGTTTAGTAGTTGTAAATAGCCCGC
AATTAGCAGAAGACCTTCACTTTGTACAAAACTCAACAGGAGGTATTCTTGGCCCGCAAGATAGCTTCTTACTACTTCGT
GGTTTAAAAACATTAGGAATTCGAATGGAAGAGCATGAAACGAATTCACGCGCAATTGCTGAGTTTTTAAATAATCATCC
AAAAGTAAATAAAGTATATTACCCAGGTCTTGCATCACATCAAAACCATGAATTAGCAACAGAACAAGCAAATGGATTTG
GTGCTATTATCTCATTTGATGTAGATAGCGAAGAAACATTAAATAAAGTACTTGAGAGATTACAATACTTTACACTAGCG
GAAAGTTTAGGAGCAGTAGAAAGTTTAATTTCTATCCCATCTCAAATGACACATGCATCAATCCCAGCAGATCGTCGCAA
AGAACTAGGAATTACAGATACATTAATTCGAATTTCTGTCGGTATTGAAGACGGAGAAGATTTAATTGAAGATTTAGCAC
AAGCGTTAGCATAG

Protein sequence :
MRAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKHQGYEYSRTGNPTRAALEEMIAVLENGHAGFAFGSGMAAITA
TIMLFSKGDHVILTDDVYGGTYRVITKVLNRFGIEHTFVDTTNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTLA
KEKGLLTIIDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNSTGGILGPQDSFLLLR
GLKTLGIRMEEHETNSRAIAEFLNNHPKVNKVYYPGLASHQNHELATEQANGFGAIISFDVDSEETLNKVLERLQYFTLA
ESLGAVESLISIPSQMTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-114 61
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-115 61
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-82 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BAA_4620 YP_002868661.1 cystathionine beta-lyase BAC0207 Protein 1e-65 42