Gene Information

Name : metI (BAA_4499)
Accession : YP_002868547.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 4074514 - 4075626 bp
Length : 1113 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGTCAACTATCGAAACAAAACTAGCGCAAATCGGAAACCGGAGTGAAACTACAACAGGAACTGTTAATCCGCCTGTTTA
CTTTTCAACTGCTTATCGTCACGAAGGAATTGGTAAATCTACTGGATTTGACTATTCACGAACTGGAAATCCAACTCGCG
GCCTATTAGAACAGGCAATCGCAGACTTAGAATACGGCGAACAAGGTTATGCCTGTAGTTCCGGTATGGCAGCTGTGCTC
CTTGTCCTTTCCCTATTCCGCTCTGGAGACGAACTTATTGTATCCGAAGATTTATACGGGGGCACTTATCGATTATTTTC
TGAGCACGAAAAAAAGTGGAATGTTCGATGTAGATACGTAAATACACAATCTATTAAACAAATTGAGCAAGCTATCACAA
CTGAAACGAAAGCTATTTTCATAGAAACCCCGACAAATCCATTAATGCAAGTTACTGATATTGCCGCTGTCGCAACTGTA
GCAAAAAGACACGGACTACTTCTTATTGTAGACAACACATTCTACACGCCTTATATACAGCAGCCATTAACAGAAGGTGC
TGACATTGTACTTCATAGCGCAACAAAATATTTAGGAGGACATAACGATGTACTAAGCGGACTTGTCGTTGCAAAAGGAA
AGGAACTTTGTGAGGAAATCGCCCATTATCATAATGCATCAGGTGCGGTCTTAAGTCCATTTGACTCATGGCTATTAATC
CGTGGTATGAAAACGTTAGCGCTTCGCATGAGACAACATGAAAAAAATGCAAAAGCAGTTGTTGCTTATTTAAATGATGA
GGACGGGGTGACAGATGTATTTTATCCTGGAAGAGGCGGCATGATCTCATTTCGTCTTAAAGATGAAACATGGATTAATC
CATTCTTACAATCTTTATCCTTAATTACATTCGCCGAAAGTCTTGGTGGTGTTGAAAGTTTAATGACATATCCAGCAACA
CAAACACACGCTGATATTCCTGAAGAAATCAGAACAGCAAACGGTGTATGTAATCGTCTTCTTCGATTTTCTGTTGGCAT
TGAAAATAGTAACGATTTAATTCAAGACTTACAGCAAGCCATTAAACTTGTAAAAGAAGGTGTAAGAATATGA

Protein sequence :
MSTIETKLAQIGNRSETTTGTVNPPVYFSTAYRHEGIGKSTGFDYSRTGNPTRGLLEQAIADLEYGEQGYACSSGMAAVL
LVLSLFRSGDELIVSEDLYGGTYRLFSEHEKKWNVRCRYVNTQSIKQIEQAITTETKAIFIETPTNPLMQVTDIAAVATV
AKRHGLLLIVDNTFYTPYIQQPLTEGADIVLHSATKYLGGHNDVLSGLVVAKGKELCEEIAHYHNASGAVLSPFDSWLLI
RGMKTLALRMRQHEKNAKAVVAYLNDEDGVTDVFYPGRGGMISFRLKDETWINPFLQSLSLITFAESLGGVESLMTYPAT
QTHADIPEEIRTANGVCNRLLRFSVGIENSNDLIQDLQQAIKLVKEGVRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-73 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-74 45