Gene Information

Name : tkt2 (BAA_3769)
Accession : YP_002867868.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3443742 - 3445784 bp
Length : 2043 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTATAAAACGTTTACTAATATAAGCGAAGGGAAGAATAGCATGTCACATTCAATCGAACAACTTTCTATCAACACGAT
TCGCACATTATCCATCGATGCGATTGAAAAAGCAAACTCTGGTCACCCAGGAATGCCAATGGGTGCAGCACCAATGGCTT
ATACATTATGGACTCAATTTATGAAACACAATCCAAATAACCCAACGTGGTTTAACCGTGATCGTTTCGTATTATCTGCA
GGTCATGGTTCAATGTTATTATACAGCCTACTTCACCTATCTGGTTATGATGTAACAATGGATGACTTAAAGAACTTCCG
TCAATGGGGAAGCAAAACTCCAGGGCATCCTGAGTACGGTCATACAGCTGGTGTAGATGCAACTACTGGTCCACTTGGAC
AAGGTATTGCAACTGCTGTAGGTATGGCAATGGCAGAAAGACATTTAGCTGCTAAATATAACCGTGATGCGTATAATATA
GTAGATCATTATACATACGCTATTTGTGGTGATGGAGATTTAATGGAAGGCGTTTCTGCTGAAGCATCTTCATTAGCTGC
TCATTTACAATTAGGTCGTCTTGTTGTGCTTTATGATTCAAACGATATTTCATTAGATGGCGATTTAAATCGTTCATTCT
CTGAAAGTGTAGAAGATCGTTACAAAGCATACGGATGGCAAGTAATCCGTGTTGAGGATGGAAACGATATTGAAGCTATC
GCGAAAGCAATCGAAGAAGCGAAAGCTGACGAAAAACGCCCAACGCTAATTGAAGTAAGAACGACAATTGGTTTCGGTTC
TCCAAACAAATCAGGAAAATCAGCTTCACATGGTTCTCCACTTGGTGTAGAAGAAACAAAGTTAACGAAAGAAGCATACG
CTTGGACTGCTGAACAAGACTTCCATGTAGCAGAAGAAGTATATGAAAACTTCCGTAAAACAGTACAAGATGTTGGTGAA
ACTGCACAAGCTGAGTGGAATACTATGCTAGGTGAATATGCACAAGCATATCCAGAATTAGCAAACGAACTGCAAGCAGC
AATGAACGGTCTTCTTCCAGAAGGTTGGGAGCAAAACTTACCAACTTATGAATTAGGATCAAAAGCAGCAACTCGTAATT
CTTCAGGTGCTGTAATTAATGCAATTGCAGAGTCTGTACCATCATTCTTCGGTGGATCTGCTGACCTTGCTGGTTCTAAC
AAAACATACATGAATAACGAAAAAGACTTTACAAGAGATGATTACAGCGGTAAAAACATTTGGTACGGTGTACGTGAGTT
CGCAATGGGTGCAGCAATGAACGGTATTGCACTACATGGTGGTTTAAAAACTTACGGTGGTACGTTCTTCGTATTCTCTG
ACTACTTACGCCCAGCAATTCGTCTTGCAGCATTAATGCAATTGCCGGTAACGTATGTATTCACACACGACAGTATCGCT
GTTGGTGAAGATGGTCCAACACATGAACCAATCGAGCAATTAGCAGCGCTACGTGCAATGCCAAATGTATCTGTTATTCG
TCCAGCTGACGGTAACGAATCTGTTGCAGCTTGGAGACTAGCTCTAGAATCTACAAACAAACCAACTGCTTTAGTATTAA
CTCGTCAAGATCTTCCAACATTAGAAGGTGCAAAAGACGATACGTATGAAAAAGTAGCAAAAGGTGCGTATGTAGTTTCT
GCAAGCAAGAAAGAAACAGCTGATGTAATCTTACTTGCAACTGGATCTGAAGTAAGTCTAGCTGTTGAAGCTCAAAAAGC
ATTAGCAGTAGACGGCGTTGATGCATCTGTTGTCAGCATGCCATCTATGGATCGCTTTGAAGCTCAAACAGCTGAGTACA
AAGAATCTGTATTACCAAAAGCAGTAACAAAACGTTTCGCAATCGAAATGGGTGCTACATTCGGATGGCACCGTTACGTA
GGTCTTGAAGGAGATGTGTTAGGTATCGATACATTCGGTGCTTCTGCTCCTGGTGAGAAGATTATGGAAGAGTATGGATT
TACTGTAGAGAACGTTGTTCGTAAAGTAAAAGAAATGCTTTAA

Protein sequence :
MYKTFTNISEGKNSMSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRDRFVLSA
GHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNI
VDHYTYAICGDGDLMEGVSAEASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAI
AKAIEEAKADEKRPTLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKTVQDVGE
TAQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSN
KTYMNNEKDFTRDDYSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIA
VGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAKGAYVVS
ASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYV
GLEGDVLGIDTFGASAPGEKIMEEYGFTVENVVRKVKEML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 8e-156 50
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-155 50