Gene Information

Name : dhaS (BAA_3638)
Accession : YP_002867748.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD)
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3318304 - 3319788 bp
Length : 1485 bp
Strand : +
Note : identified by match to protein family HMM PF00171

DNA sequence : 
ATGAGTCAACTAGCTGTAAATCTTCATGAAAAGGTAGAAAAGTTTCTTCAAGGTACGAAAAAGTTATATGTGAATGGATC
ATTCATTGAAAGCGCTTCCGGTAAGACGTTTAATACACCTAATCCAGCAACTGGCGAAACACTTGCCGTCGTTTCTGAAG
CCGGTCGCGAAGATATTCATAAAGCTGTAGTTGCAGCTCGCATGGCTTTTGACGAAGGTCCTTGGTCTCGCATGAGCACT
GCGGAGCGAAGCCGTCTTATGTACAAGTTAGCTGATTTAATGGAAGAACATAAAGAAGAGCTTGCACAGCTCGAGACGTT
AGATAACGGAAAGCCAATCCGTGAAACAATGGCAGCAGACATACCACTTGCAATTGAGCACATGCGCTATTATGCTGGCT
GGGCGACGAAAATCGTTGGTCAAACAATCCCTGTTTCCGGTGATTTCTTTAACTATACACGCCATGAAGCTGTTGGTGTC
GTTGGTCAAATTATCCCTTGGAACTTCCCGCTTCTTATGGCCATGTGGAAAATGGGAGCAGCGCTTGCTACAGGATGTAC
AATCGTTTTAAAACCTGCAGAACAAACTCCACTATCTGCTCTATACTTAGCTGAATTAATTGAAGAAGCTGGATTCCCGA
AAGGCGTTATTAATATCGTTCCTGGATTCGGTGAATCAGCTGGACAAGCTCTCGTTAATCATCCACTCGTTGATAAAATT
GCATTTACCGGTTCTACTCCAGTCGGTAAACAAATTATGCGACAAGCATCTGAATCCTTGAAACGTGTTACTTTAGAGCT
TGGTGGTAAATCACCGAACATTATTTTACCAGACGCTGATTTATCTCGCGCAATTCCTGGTGCACTTTCTGGTGTTATGT
TTAACCAAGGGCAAGTATGCTCTGCTGGATCACGCCTATTTGTTCCGAAGAAAATGTATGATAATGTCATGGCTGATCTC
GTCCTCTATTCTAAAAAACTAAATCAAGGTGTCGGTCTTGACCCTGAAACGACAATTGGTCCTCTCGTTTCCGAAGAACA
ACAAAAACGTGTAATGGGCTACATTGAAAAAGGGATTGAAGAAGGCGCTGAAGTACTTTGCGGAGGAAATAATCCATTCG
ATCAAGGCTACTTCATTTCTCCTACAGTATTCGCTGACGTAAATGACGAAATGACAATCGCAAAAGAAGAAATTTTCGGT
CCAGTTATTTCTGCAATACCTTTTAACGATATTGATGAAGTAATTGAACGAGCAAATAAATCACAATTCGGCTTAGCGGC
TGGTGTGTGGACAGAAAATGTTAAAACAGCACACTATGTTGCAAGTAAAGTACGTGCAGGTACAGTATGGGTTAACTGTT
ACAACGTCTTTGATGCAGCATCTCCATTTGGAGGATTTAAACAATCTGGTCTCGGCCGTGAAATGGGATCTTACGCATTA
AATAACTATACAGAAGTGAAGAGCGTTTGGCTTAACTTAAATTAA

Protein sequence : 
MSQLAVNLHEKVEKFLQGTKKLYVNGSFIESASGKTFNTPNPATGETLAVVSEAGREDIHKAVVAARMAFDEGPWSRMST
AERSRLMYKLADLMEEHKEELAQLETLDNGKPIRETMAADIPLAIEHMRYYAGWATKIVGQTIPVSGDFFNYTRHEAVGV
VGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQTPLSALYLAELIEEAGFPKGVINIVPGFGESAGQALVNHPLVDKI
AFTGSTPVGKQIMRQASESLKRVTLELGGKSPNIILPDADLSRAIPGALSGVMFNQGQVCSAGSRLFVPKKMYDNVMADL
VLYSKKLNQGVGLDPETTIGPLVSEEQQKRVMGYIEKGIEEGAEVLCGGNNPFDQGYFISPTVFADVNDEMTIAKEEIFG
PVISAIPFNDIDEVIERANKSQFGLAAGVWTENVKTAHYVASKVRAGTVWVNCYNVFDAASPFGGFKQSGLGREMGSYAL
NNYTEVKSVWLNLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-96 47
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-93 45
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-95 45
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-95 45
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-95 45
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-94 45
hpaE AAO17179.1 HpaE Not tested tcd island Protein 4e-81 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhaS YP_002867748.1 aldehyde dehydrogenase (NAD) VFG0082 Protein 4e-94 45