Gene Information

Name : alo (BAA_3389)
Accession : YP_002867524.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Virulence
Product : anthrolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3086326 - 3087864 bp
Length : 1539 bp
Strand : -
Note : identified by match to protein family HMM PF01289

DNA sequence :
GTGATTTTTCTGAATATTAAGAAAAACACTAAAAGAAGAAAGTTCCTTGCATGTTTATTAGTTAGTCTATGTACCATTCA
TTATTCGTCTATTTCTTTTGCAGAAACACAAGCCGGTAATGCAACTGGTGCAATAAAAAATGCTAGTGATATTAATACTG
GTATAGCAAATCTAAAGTATGATAGTAGAGATATTTTAGCAGTAAATGGTGATAAAGTAGAGAGTTTTATTCCGAAAGAG
AGTATCAATTCAAACGGTAAATTTGTAGTAGTGGAACGCGAGAAAAAATCACTTACAACGTCACCAGTCGATATTTTGAT
TATTGATTCTGTAGTGAATCGTACGTATCCAGGAGCTGTACAACTTGCCAATAAAGCATTTGCAGACAATCAACCGAGTT
TATTAGTAGCTAAGAGAAAGCCTTTGAATATTAGTATAGACTTACCTGGCATGAGAAAAGAAAATACAATCACTGTCCAA
AATCCGACATATGGTAATGTGGCTGGAGCAGTAGATGATTTAGTATCTACTTGGAATGAAAAGTATTCCACAACACATAC
GTTACCTGCAAGAATGCAGTATACAGAATCTATGGTTTATAGTAAATCACAAATCGCAAGTGCTCTTAATGTTAATGCTA
AATATCTTGATAACAGTCTAAATATTGACTTTAATGCAGTTGCAAATGGAGAAAAGAAAGTGATGGTGGCGGCATATAAA
CAAATATTTTATACTGTAAGTGCTGAACTACCTAATAATCCATCTGATCTCTTTGATAATAGTGTTACTTTTGATGAGTT
AACTCGTAAAGGAGTAAGTAATTCGGCTCCACCTGTTATGGTTTCAAATGTAGCTTATGGTAGAACGGTTTATGTAAAAT
TAGAAACAACATCTAAGAGTAAAGATGTACAAGCTGCATTTAAAGCTCTACTTAAGAATAACAGCGTCGAAACGAGTGGA
CAGTACAAAGATATTTTTGAAGAAAGTACCTTTACTGCTGTAGTATTAGGCGGAGATGCGAAAGAGCATAACAAGGTTGT
TACAAAAGATTTCAATGAAATCCGAAATATTATTAAAGATAATGCTGAATTAAGCTTTAAAAATCCAGCATACCCAATTT
CATATACAAGCACGTTCTTAAAAGATAATGCAACTGCTGCTGTTCATAACAATACAGATTATATCGAGACGACAACTACA
GAATATTCAAGTGCTAAAATGACACTCGATCATTACGGTGCTTACGTTGCTCAATTTGATGTATCTTGGGATGAATTTAC
ATTTGATCAAAATGGGAAAGAAGTACTAACACATAAAACATGGGAAGGTAGTGGCAAAGACAAAACAGCCCATTACTCTA
CAGTTATCCCTCTTCCACCAAATTCAAAAAATATAAAAATCGTTGCAAGAGAATGTACAGGTCTTGCATGGGAATGGTGG
AGAACTATCATTAATGAACAAAATGTTCCATTAACAAATGAAATAAAGGTTTCAATTGGAGGAACAACATTATATCCAAC
TGCTACTATTAGTCATTAG

Protein sequence :
MIFLNIKKNTKRRKFLACLLVSLCTIHYSSISFAETQAGNATGAIKNASDINTGIANLKYDSRDILAVNGDKVESFIPKE
SINSNGKFVVVEREKKSLTTSPVDILIIDSVVNRTYPGAVQLANKAFADNQPSLLVAKRKPLNISIDLPGMRKENTITVQ
NPTYGNVAGAVDDLVSTWNEKYSTTHTLPARMQYTESMVYSKSQIASALNVNAKYLDNSLNIDFNAVANGEKKVMVAAYK
QIFYTVSAELPNNPSDLFDNSVTFDELTRKGVSNSAPPVMVSNVAYGRTVYVKLETTSKSKDVQAAFKALLKNNSVETSG
QYKDIFEESTFTAVVLGGDAKEHNKVVTKDFNEIRNIIKDNAELSFKNPAYPISYTSTFLKDNATAAVHNNTDYIETTTT
EYSSAKMTLDHYGAYVAQFDVSWDEFTFDQNGKEVLTHKTWEGSGKDKTAHYSTVIPLPPNSKNIKIVARECTGLAWEWW
RTIINEQNVPLTNEIKVSIGGTTLYPTATISH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 8e-150 62
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 2e-100 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
alo YP_002867524.1 anthrolysin O VFG2275 Protein 5e-172 69
alo YP_002867524.1 anthrolysin O VFG0976 Protein 3e-150 62
alo YP_002867524.1 anthrolysin O VFG1363 Protein 6e-102 43
alo YP_002867524.1 anthrolysin O VFG0074 Protein 1e-100 42